UniProtKB - Q8IBB6 (Q8IBB6_PLAF7)
Protein
eIF-2B GDP-GTP exchange factor subunit alpha
Gene
PF3D7_0828500
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
GO - Molecular functioni
- translation initiation factor activity Source: UniProtKB-KW
GO - Biological processi
- regulation of translational initiation Source: GO_Central
- translational initiation Source: GO_Central
Keywordsi
Molecular function | Initiation factorImportedARBA annotation |
Biological process | Protein biosynthesis |
Enzyme and pathway databases
Reactomei | R-PFA-72731, Recycling of eIF2:GDP |
Names & Taxonomyi
Protein namesi | Recommended name: eIF-2B GDP-GTP exchange factor subunit alphaARBA annotation |
Gene namesi | ORF Names:PF3D7_0828500Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0828500 |
Subcellular locationi
GO - Cellular componenti
- eukaryotic translation initiation factor 2B complex Source: GO_Central
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
HOGENOMi | CLU_812550_0_0_1 |
InParanoidi | Q8IBB6 |
OMAi | VRFRVIY |
PhylomeDBi | Q8IBB6 |
Family and domain databases
Gene3Di | 1.20.120.1070, 1 hit 3.40.50.10470, 1 hit |
InterProi | View protein in InterPro IPR042528, elF-2B_alpha_N IPR000649, IF-2B-related IPR042529, IF_2B-like_C IPR037171, NagB/RpiA_transferase-like |
Pfami | View protein in Pfam PF01008, IF-2B, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
i Sequence
Sequence statusi: Complete.
Q8IBB6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MECYDNTKQK DLQEEHDVVR NFRRYYFQEK EEMHIAAIKS ISDVLKNSIS
60 70 80 90 100
ETNFELFINM NEAKCKLNNF INNNQTQQDI ISVPHSKRMT IYPIISSCDI
110 120 130 140 150
YHHFVVKKYT HNENNFHVLK NVIENNADEF SASLQKSLET IGSSSNIMFL
160 170 180 190 200
NKHTTILTHS NSDCVKSLIM DVVKNQNKQV SIYFTCTSQV NLNYEEKEKK
210 220 230 240 250
FDENFLEELN KENINITKID LTQVKDIINK IDFVLIGSEI VTDNGGIINK
260 270 280 290 300
KGIKLISELC LLYKKPFYVT CQAYKFLKID KNKCSKDFYT FCTQTVTNNF
310 320 330 340
NNIYEFVSPD FITLFYTDIG IFPPSNISYE LSKLYINDAF YF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844507 Genomic DNA Translation: CAD51090.1 |
RefSeqi | XP_001349241.1, XM_001349205.1 |
Genome annotation databases
EnsemblProtistsi | CAD51090; CAD51090; PF3D7_0828500 |
GeneDBi | PF3D7_0828500.1:pep |
GeneIDi | 2655458 |
KEGGi | pfa:PF3D7_0828500 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844507 Genomic DNA Translation: CAD51090.1 |
RefSeqi | XP_001349241.1, XM_001349205.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | Q8IBB6, 5 interactors |
PTM databases
SwissPalmi | Q8IBB6 |
Proteomic databases
PRIDEi | Q8IBB6 |
Genome annotation databases
EnsemblProtistsi | CAD51090; CAD51090; PF3D7_0828500 |
GeneDBi | PF3D7_0828500.1:pep |
GeneIDi | 2655458 |
KEGGi | pfa:PF3D7_0828500 |
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0828500 |
Phylogenomic databases
HOGENOMi | CLU_812550_0_0_1 |
InParanoidi | Q8IBB6 |
OMAi | VRFRVIY |
PhylomeDBi | Q8IBB6 |
Enzyme and pathway databases
Reactomei | R-PFA-72731, Recycling of eIF2:GDP |
Family and domain databases
Gene3Di | 1.20.120.1070, 1 hit 3.40.50.10470, 1 hit |
InterProi | View protein in InterPro IPR042528, elF-2B_alpha_N IPR000649, IF-2B-related IPR042529, IF_2B-like_C IPR037171, NagB/RpiA_transferase-like |
Pfami | View protein in Pfam PF01008, IF-2B, 1 hit |
SUPFAMi | SSF100950, SSF100950, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8IBB6_PLAF7 | |
Accessioni | Q8IBB6Primary (citable) accession number: Q8IBB6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 121 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |