UniProtKB - Q8IB73 (Q8IB73_PLAF7)
Protein
Submitted name:
Dicarboxylate/tricarboxylate carrier
Gene
PF3D7_0823900
Organism
Plasmodium falciparum (isolate 3D7)
Status
Functioni
GO - Molecular functioni
- dicarboxylic acid transmembrane transporter activity Source: GeneDB
- oxoglutarate:malate antiporter activity Source: GeneDB
GO - Biological processi
- alpha-ketoglutarate transport Source: GeneDB
- dicarboxylic acid transport Source: GeneDB
- malate transport Source: GeneDB
- mitochondrial transport Source: GeneDB
Keywordsi
Biological process | TransportUniRule annotation |
Protein family/group databases
TCDBi | 2.A.29.2.10, the mitochondrial carrier (mc) family |
Names & Taxonomyi
Protein namesi | Submitted name: Dicarboxylate/tricarboxylate carrierImported |
Gene namesi | ORF Names:PF3D7_0823900Imported |
Organismi | Plasmodium falciparum (isolate 3D7)Imported |
Taxonomic identifieri | 36329 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0823900 |
Subcellular locationi
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 228 – 248 | HelicalSequence analysisAdd BLAST | 21 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-UniRule
- mitochondrial inner membrane Source: GeneDB
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 29 – 116 | SolcarPROSITE-ProRule annotationAdd BLAST | 88 | |
Repeati | 124 – 215 | SolcarPROSITE-ProRule annotationAdd BLAST | 92 | |
Repeati | 222 – 313 | SolcarPROSITE-ProRule annotationAdd BLAST | 92 |
Sequence similaritiesi
Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
HOGENOMi | CLU_015166_14_1_1 |
InParanoidi | Q8IB73 |
OMAi | FLHTPFM |
PhylomeDBi | Q8IB73 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
Q8IB73-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDRDIAKYDL ESSSSVDVNK KGNNNKSVFE KIKPFAVGGA SGMFATFCIQ
60 70 80 90 100
PLDMVKVRIQ LNAEGKNVLR NPFIVAKDII KNEGFLSLYK GLDAGLTRQV
110 120 130 140 150
IYTTGRLGLF RTFSDMVKKE GEPLPFYKKC FCALAAGGLG AFIGNPADLS
160 170 180 190 200
LIRLQADNTL PKELKRNYTG VFNALYRISK EEGLFALWKG SVPTIARAMS
210 220 230 240 250
LNLGMLSTYD QSKEFLQKYL GVGMKTNLVA SVISGFFAVT LSLPFDFVKT
260 270 280 290 300
CMQKMKADPV TKKMPYKNML DCSIQLYKKG GISIFYSSYA TYYVRIAPHA
310
MITLITVDYL NNLLKKIS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844507 Genomic DNA Translation: CAD51134.1 |
RefSeqi | XP_001349285.1, XM_001349249.1 |
Genome annotation databases
EnsemblProtistsi | CAD51134; CAD51134; PF3D7_0823900 |
GeneDBi | PF3D7_0823900.1:pep |
GeneIDi | 2655481 |
KEGGi | pfa:PF3D7_0823900 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL844507 Genomic DNA Translation: CAD51134.1 |
RefSeqi | XP_001349285.1, XM_001349249.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
TCDBi | 2.A.29.2.10, the mitochondrial carrier (mc) family |
PTM databases
SwissPalmi | Q8IB73 |
Proteomic databases
PRIDEi | Q8IB73 |
Genome annotation databases
EnsemblProtistsi | CAD51134; CAD51134; PF3D7_0823900 |
GeneDBi | PF3D7_0823900.1:pep |
GeneIDi | 2655481 |
KEGGi | pfa:PF3D7_0823900 |
Organism-specific databases
EuPathDBi | PlasmoDB:PF3D7_0823900 |
Phylogenomic databases
HOGENOMi | CLU_015166_14_1_1 |
InParanoidi | Q8IB73 |
OMAi | FLHTPFM |
PhylomeDBi | Q8IB73 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8IB73_PLAF7 | |
Accessioni | Q8IB73Primary (citable) accession number: Q8IB73 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |