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Protein
Submitted name:

Ubiquitin-conjugating enzyme, putative

Gene

PF3D7_0812600

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei88Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseSAAS annotation
Biological processUbl conjugation pathwayUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-PFA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
R-PFA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-conjugating enzyme, putativeImported
Gene namesi
ORF Names:PF3D7_0812600Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0812600

Subcellular locationi

GO - Cellular componenti

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ8IAW2, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ8IAW2
SMRiQ8IAW2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 139UBIQUITIN_CONJUGAT_2InterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000233454
InParanoidiQ8IAW2
KOiK10573
OMAiRENMKEY
PhylomeDBiQ8IAW2

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8IAW2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSNLAKKRLI RDFRKLQTDS PFGVSGSPIG NDIMKWRAVI FGPADTPWEG
60 70 80 90 100
GTFHLELLFG NEYPNRPPKV KFLTKMFHPN IYMDGNICID ILQKHWSPIY
110 120 130 140 150
DISAILTSIQ SLLSDPNPNS PANQEAALLF VENRIEYNRR IKNCVKESFN
160
FIEQKAEEDA EKS
Length:163
Mass (Da):18,687
Last modified:March 1, 2003 - v1
Checksum:iD1D2DBE377582EA9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844507 Genomic DNA Translation: CAD51248.1
RefSeqiXP_001349399.1, XM_001349363.1

Genome annotation databases

EnsemblProtistsiCAD51248; CAD51248; PF3D7_0812600
GeneDBiPF3D7_0812600.1:pep
GeneIDi2655284
KEGGipfa:PF3D7_0812600

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844507 Genomic DNA Translation: CAD51248.1
RefSeqiXP_001349399.1, XM_001349363.1

3D structure databases

ProteinModelPortaliQ8IAW2
SMRiQ8IAW2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8IAW2, 1 interactor

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAD51248; CAD51248; PF3D7_0812600
GeneDBiPF3D7_0812600.1:pep
GeneIDi2655284
KEGGipfa:PF3D7_0812600

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0812600

Phylogenomic databases

HOGENOMiHOG000233454
InParanoidiQ8IAW2
KOiK10573
OMAiRENMKEY
PhylomeDBiQ8IAW2

Enzyme and pathway databases

ReactomeiR-PFA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
R-PFA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ8IAW2_PLAF7
AccessioniPrimary (citable) accession number: Q8IAW2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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