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UniProtKB - Q8I4W9 (Q8I4W9_PLAF7)

Entry version 83 (31 Jul 2019)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

PF3D7_1246300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-PFA-8856825 Cargo recognition for clathrin-mediated endocytosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_1246300Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Laverania) ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		PlasmoDB:PF3D7_1246300

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

PTM databases

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q8I4W9

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8I4W9

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni358 – 454DisorderedSequence analysisAdd BLAST97

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi358 – 417PolyampholyteSequence analysisAdd BLAST60
Compositional biasi424 – 453PolyampholyteSequence analysisAdd BLAST30

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...OMAi		KGFPLIK

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013041 Clathrin_app_Ig-like_sf

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49348 SSF49348, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8I4W9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAICKGKYKN AGSTSDQLLF QNCCESTEYL NLYFKDLKDY LIRYNKFEEL 
        60         70         80         90        100
YNYCYNVLTN VQNNSPLSRI TSLKVANLGV IINEKNVSYL VNKDILKYAY 
       110        120        130        140        150
KILKRNKEGK NKKFATYFGD ITNIERNILS RECEYLFRNL SHINIVKNTK 
       160        170        180        190        200
EEKYINNLKN KIEKNKISIP QKANDSLSYV LILSDFNKCK REILDCLDNE 
       210        220        230        240        250
FVNHNKLDSV YSSYVMLLKE LKEKTVKFLQ NGDYHLYCNF HDEIQEEHEI 
       260        270        280        290        300
NIRYESYLES FTSNKSEKKE LKPINKQNTL KSEGEKKNKL MNVNSNVSST 
       310        320        330        340        350
CTENNNVDVF FPKCHNNNEI SLKNNNNSNN SENKSLSKNL SSTFTTFAMS 
       360        370        380        390        400
LNKKIFNDKS DQNEKHDNEK DNLDMLKINE QGKADDIDKT KKEKTEENEI 
       410        420        430        440        450
ENIDNEKKKD EQIENIKKQS SNKTVAFKMD KDDPNKNQPN DKTKNKDNGN 
       460        470        480        490        500
KEGESFNKIQ NEIINEFNSF LNEENDVMYF DKINGHKYLE FKNNVSDGNS 
       510        520        530        540        550
ALWENLIKKS NFYQIKEDFE NYNKIMKQQE ENEHDKGNEE KTLGDLLGMN 
       560        570        580        590        600
KYESIKNKNI KDLKSTTLNT DDFCHIIKNF NINNMNGHVN LENYPLNINN 
       610        620        630        640        650
KDNHFVADNL VQPTNTLNVF PDTNIKLDNK QEENGALNPL NKYFTMHDNI 
       660        670        680        690        700
YYIQKAILKN NSVLYKDDNI EISLDQYYYD LNGLVKIFLK NKKIVNCYDV 
       710        720        730        740        750
DIQISNKMLF PLKMKFLNFE KTLSMNSTNC YEIAVKCLHI YKGFPLIKVS 
       760        770        780        790        800
YRMQDMFKKT IELRLPIPIT KYMKKMEISK DVFNKFWSNN NFNEYKKEKI 
       810        820        830        840        850
INKSDIVDNE LIVMDSCLGG ALGLCYVENM IYLCGCYTNS SAGHENYFVL 
       860        870        880 
VGIEMIKKKL RIVCKSNNPT LSSAILFLIV LMHKKHET
Length:888
Mass (Da):104,015
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C33A780A8065CAA
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
LN999947 Genomic DNA Translation: CZT99617.1

NCBI Reference Sequences

More...RefSeqi		XP_001350848.1, XM_001350812.1

Genome annotation databases

Ensembl protists genome annotation project

More...EnsemblProtistsi		CZT99617; CZT99617; PF3D7_1246300

GeneDB pathogen genome database from Sanger Institute

More...GeneDBi		PF3D7_1246300.1:pep

Database of genes from NCBI RefSeq genomes

More...GeneIDi		811496

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		pfa:PF3D7_1246300

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LN999947 Genomic DNA Translation: CZT99617.1
RefSeqiXP_001350848.1, XM_001350812.1

3D structure databases

SMRiQ8I4W9
ModBaseiSearch...

PTM databases

SwissPalmiQ8I4W9

Genome annotation databases

EnsemblProtistsiCZT99617; CZT99617; PF3D7_1246300
GeneDBiPF3D7_1246300.1:pep
GeneIDi811496
KEGGipfa:PF3D7_1246300

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_1246300

Phylogenomic databases

OMAiKGFPLIK

Enzyme and pathway databases

ReactomeiR-PFA-8856825 Cargo recognition for clathrin-mediated endocytosis

Family and domain databases

InterProiView protein in InterPro
IPR013041 Clathrin_app_Ig-like_sf
SUPFAMiSSF49348 SSF49348, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8I4W9_PLAF7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8I4W9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 31, 2019
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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