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Entry version 74 (31 Jul 2019)
Sequence version 1 (01 Mar 2003)
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Protein
Submitted name:

Uncharacterized protein

Gene

PF3D7_0508900

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PLASMO:PFE0440W-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PF3D7_0508900Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium falciparum (isolate 3D7)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri36329 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001450 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
PlasmoDB:PF3D7_0508900

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
Q8I414

PTM databases

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q8I414

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8I414, 1 interactor

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni714 – 797DisorderedSequence analysisAdd BLAST84
Regioni817 – 844DisorderedSequence analysisAdd BLAST28
Regioni931 – 965DisorderedSequence analysisAdd BLAST35
Regioni1739 – 1801DisorderedSequence analysisAdd BLAST63
Regioni2335 – 2371DisorderedSequence analysisAdd BLAST37
Regioni2476 – 2771DisorderedSequence analysisAdd BLAST296

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili660 – 680Sequence analysisAdd BLAST21
Coiled coili862 – 882Sequence analysisAdd BLAST21
Coiled coili1520 – 1540Sequence analysisAdd BLAST21
Coiled coili2875 – 2895Sequence analysisAdd BLAST21
Coiled coili3073 – 3093Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi728 – 745PolarSequence analysisAdd BLAST18
Compositional biasi746 – 794PolyampholyteSequence analysisAdd BLAST49
Compositional biasi931 – 954PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1739 – 1759PolyampholyteSequence analysisAdd BLAST21
Compositional biasi1760 – 1799PolarSequence analysisAdd BLAST40
Compositional biasi2487 – 2771AcidicSequence analysisAdd BLAST285

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8I414

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNIKGED

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8I414-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTCNNIVDL VRNKKELLTG EKKMRKKSCN IDRNTIDNEN NKLLDKNILI
60 70 80 90 100
NNFLNSEKLI KEIQLLNNIS LRSATYLLKI EIEKIQKLIS CNNWKQVPSI
110 120 130 140 150
YKKSAENILL KKNEYIKNLK TKLLNKNKAI QNNINNDNID NIDNIYNSCY
160 170 180 190 200
NLVNKNDEKK FSKHLNSSSS SSSLSSYSSL SNPSDDSCFS NKQNQNNFFS
210 220 230 240 250
NIKCNNSYFT GNAQTKNKLD NHTSKKKTKI NDKIYDKIYD KINDKICDKK
260 270 280 290 300
YDKIYDKKYD KKYDKICDKI CDKKYDKIYD KKYDKKYDKI YDKICDKKND
310 320 330 340 350
IKNDKNIKTF NVKGKDTKII KLDKEHVKDK INYNYSNKII NYKGNFYDNN
360 370 380 390 400
NKNEIKNNEY YYYDDEQDLD SYNGLCYTNG KNNIFCFLNP QENQKDDKIN
410 420 430 440 450
IDSNHNYMYN NTHSNNDHID SYHPNGYGDK VISYEKKEGR KLHTNNLINN
460 470 480 490 500
MGTINKREEE TKGSSVFSIN NEHCGTTKFI KSASVCNFSC GNLFKNPKKD
510 520 530 540 550
EDIYTNKMIG SECFNLKTGT NVSKNTKKII PNFERHTVSS FIKNLSAQKN
560 570 580 590 600
LQEKINNQHM MIKKNIYEKK DRRASTNTCC STLGNTFTKR QVQKNYTNDM
610 620 630 640 650
DDTYNINKLK CIKQKNNHKY ENNEYANCDH YDDYNNMNTN HMDLKNSHDH
660 670 680 690 700
YINDDKILVY KELLNNIRNK KNEKYNIRKK SKFSIEKKID LFHMNSLNED
710 720 730 740 750
YSWVKNLRNY DHTGEKKNQK KNSLQKKKFI PGRQSNVLND SYDDNSGMIN
760 770 780 790 800
EKKKKKEKQK QNEKEKEKEK EKEKEKKKQN EKEKEKEKQN EKQTNKQMNK
810 820 830 840 850
QMNKQMNKQM NKQMNKPINK PINKPINKPI NKPINKPINK PINKPINKQI
860 870 880 890 900
NKQWDEPKYT SISKLNNNHT NVEHNMNNME YEDCNENYAS YNHSECNIIY
910 920 930 940 950
PVINKSLDMD VKKEDIKKNV EENKYIEHTQ NLKNYLENDE NEKKKRRKRS
960 970 980 990 1000
NNNDNYNSHD NNIFQNNHHS NIDMWSHKHI TLPRVYEKKN NSLIYNHQIN
1010 1020 1030 1040 1050
LEDKIPLKKI NQRKSYMIQE NDQHMKYLLN KNEEAKYFEL LISSSKNNIQ
1060 1070 1080 1090 1100
PYEQPSGIMN TSNIDHNIAD EHITGCMNNI FTNNNNKKKN NNNNKNNNKN
1110 1120 1130 1140 1150
NKYVNIKLQG NKLMLNNDLN INKKESNNIT KENNFHIHNN NNNKKHKHSS
1160 1170 1180 1190 1200
IIINDINHKF QKDQEDQHVQ VNSIFYLPEK NNIKSMDNHM YNNTYSNEHN
1210 1220 1230 1240 1250
NYIHSLSDNK SKKTNEQVSN ILNINKYVTK EYSQNHVKEQ NQLFPTINTF
1260 1270 1280 1290 1300
QNHNNIICNK IIHEPLKNIS FHNHLADHTD INADEFSGTK TLTIYNHHLI
1310 1320 1330 1340 1350
KGNENNDMYK DNFNSHDKNI TNPLSISKEN KKKMNTIDIN QYNDNVECFH
1360 1370 1380 1390 1400
NLNLPKRSHT TIIPNYLHNK EKKINNDNND NNINIVSTNN NLVLFKKNYL
1410 1420 1430 1440 1450
EEENNIVNNK IKNNEYILSN QEKQITNIKK DISFNKNIFY PEEGNYNNEH
1460 1470 1480 1490 1500
EHTQTYINII ENKKSIHMND VKNSNIKQVP ELSSNKDNFI MIKDVIQIPK
1510 1520 1530 1540 1550
LNLDNIKNKK GKNFNSYQIK ETKEMKVMEE MKEMEETKEM KEMKEMSHIH
1560 1570 1580 1590 1600
NNDVSCDNKK NKDYLSITSN LHSPFENQKN IYISNGNNNN KNSNNNQYFG
1610 1620 1630 1640 1650
QSFTNRNIVD CKMYKQNNIN QIRKSKTTTI NFENTSSKNI KDKHYLNYKI
1660 1670 1680 1690 1700
SNDNLVNNKI INNYAFKDTK NKFYNLDYDK ETVSKTSCFT CGTTTQDKHM
1710 1720 1730 1740 1750
YNNDKNSFIC NNIFHKRRPS NILNSCIFTE LDEGLSRTRH SVHDEKCNME
1760 1770 1780 1790 1800
KKKEDDDNNN NNNNNNNNNN NNNNNKSNNH INNKSNSNIH NCGQGNTTRK
1810 1820 1830 1840 1850
DNYTKHHLSE KKNVKKSFTS MILNFFGFKY DNIEEDKKSE NVSVHIMNKN
1860 1870 1880 1890 1900
NDHIITNNES KNTYNISTYI RSKSATYNNI SKNEKENKKN EIYIVHPNNN
1910 1920 1930 1940 1950
KSSTIMSLSK DSTFPFPPLT FIRNNTNKKR IASYNNSIQD LSTNEFKNQI
1960 1970 1980 1990 2000
QPNTNTSVQK RKTCDISSLS KNQSLNHLLY NNNVNTHVNH SNNMQNRNIK
2010 2020 2030 2040 2050
NSYNLEEENT KNEFLQNGHM DKNSYPKHVK LLSSYKMMET FNNNKNYITK
2060 2070 2080 2090 2100
YDTNGNYNIK CEDNIKGEDN IKGEDNIKGE DNIKGEDNIK GEDNIKGEDN
2110 2120 2130 2140 2150
IKGEDNIKGE DNIKGKDNIK CEDNIKCEDN IKGEDNNSSI YYSNILNNNI
2160 2170 2180 2190 2200
STNFMNKNGS VNTNYISQSP AQYNRPYNMN IIYNNHNNFD NTKDIKSDVN
2210 2220 2230 2240 2250
ISTLFKDLQN KNNNNNISNC NNYINNECFK INKKYDNNHN HYSINTSEKM
2260 2270 2280 2290 2300
SSNFLNKIYK ENKKEQVNYK PSYINDTISN KSTIDSPSIK CEQKKLTLKK
2310 2320 2330 2340 2350
LNNNVNAVMI NNNLTVNTHM DNIINNANGY YINQSNMHSY NNNNNNNNNN
2360 2370 2380 2390 2400
SNNNNNSNSN NNSNSNNFIN QKRDVNNMPE QFSKNKHNTI MNGNNKDYVI
2410 2420 2430 2440 2450
FNEEKEHFSN LNFKNETNQH YFTKEQLFPL KSDHLNQAHE IKHNVKQIYT
2460 2470 2480 2490 2500
THNMFCKEGE AYNMINKEKE SKKKNGKKIF MRGDEELKDN EEEEVEEEVE
2510 2520 2530 2540 2550
EEIEDDEEED EEIEDDEEEE EDEEVEDDEE EEEDEEVDDE EEEVEESDEE
2560 2570 2580 2590 2600
VECDEEVDDD EEEEEEVDDE EEEEEVEESD EEVEDDEEEE EELEDGEEEE
2610 2620 2630 2640 2650
EELEDNEEGD EEVDDEEEEE EVEESDEEVE VDEEEEEELD GDEEGDEEED
2660 2670 2680 2690 2700
NEEDDEEVGD EEEEEEVEES DEEVEDDEGE EEELEGDEEE EEEVEESDEE
2710 2720 2730 2740 2750
EEELDSDEED NEEDDEEEED LEVEDDEDVE EGELEGDEEE EEELKDGEES
2760 2770 2780 2790 2800
DEELEDSEES DEEVEDVEDN EEEIHEYYCK EEDTVMKQPY NTFEEEKTNI
2810 2820 2830 2840 2850
SFIDTHSKNI PIYNKSITSV DNLKSLNTHC AYELSPIGNQ NLKSCTMIYK
2860 2870 2880 2890 2900
DDKEENKESY EKNDKKTITL NTLNLKELRN EQENVFNKND IQQKEDKNKN
2910 2920 2930 2940 2950
IFKYRNDTEN SMSLKKTISD CEMSKSQNTL TDEENYDSNY YISQNISKYN
2960 2970 2980 2990 3000
MDKKEYEKNN QLKMSGKDIM NISSNLDKLN DKKNFYGNDM STQNSSENFS
3010 3020 3030 3040 3050
SFEKPMEINN SNYNLCNKYL NHEKDQNINS VHNLNDNNNN NNNKENNILS
3060 3070 3080 3090 3100
KDIINHNNIT DIYYNNNNSY KYFDEIAKEM EYAKNNNDDL KKKLQEQILI
3110 3120 3130
QRGLLKIKEQ QQVYLELLKK NDIKQHKENI HNII
Length:3,134
Mass (Da):370,181
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i71488B0E3E7161CB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL844504 Genomic DNA Translation: CAD51454.1

NCBI Reference Sequences

More...
RefSeqi
XP_001351647.1, XM_001351611.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAD51454; CAD51454; PF3D7_0508900

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
PF3D7_0508900.1:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
812856

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pfa:PF3D7_0508900

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA Translation: CAD51454.1
RefSeqiXP_001351647.1, XM_001351611.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ8I414, 1 interactor

PTM databases

SwissPalmiQ8I414

Proteomic databases

PRIDEiQ8I414

Genome annotation databases

EnsemblProtistsiCAD51454; CAD51454; PF3D7_0508900
GeneDBiPF3D7_0508900.1:pep
GeneIDi812856
KEGGipfa:PF3D7_0508900

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0508900

Phylogenomic databases

InParanoidiQ8I414
OMAiDNIKGED

Enzyme and pathway databases

BioCyciPLASMO:PFE0440W-MONOMER

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ8I414_PLAF7
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8I414
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 31, 2019
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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