Phosphatidylinositol 4-kinase

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• 1-phosphatidylinositol 4-kinase activity Source: GO_Central

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• phosphatidylinositol-mediated signaling Source: GO_Central
• response to drug Source: GeneDB <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayⁱ
  • 24284631

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• cytoplasm Source: GO_Central
• membrane Source: GO_Central

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MEDDKDNNIT KENLNEVDIE NSQHPIIEEK NLKEEGVKDE GGKVFLKGEP 
        60         70         80         90        100
IHKHLYKHSY NTQVYKDEVT HMRLRNRENK NLNENNSDDN KKVNKKNGCV 
       110        120        130        140        150
DINMNEHTNK KEDGDDDDGD DDDGDDDDDD DDDDGDDDGD DDGDDDGDDG 
       160        170        180        190        200
DDDSNSNDDI KNNHKYNNDD YHKNMIKLHC TSPKKKEHSI NNNNIVSHNE 
       210        220        230        240        250
IEENLKDHTL ITNDEEKNIK IIEMYEKKLE NEEIKKQNKE DANENNKSQI 
       260        270        280        290        300
RESISKIFKE CPTSKPKIIN EINNETKYDN NNNNNNNNNN NNNNSNNNNK 
       310        320        330        340        350
NNNKNNNKNS SYNNYYYNNI YNCNNMKENN HIDGDKNNIY ETNNYSDSEK 
       360        370        380        390        400
NKSSDTEKNK LKLNNKNTLK EGSLLRLFRC EYFDTHLHIR YLYDRKEVGV 
       410        420        430        440        450
HEYLVNSLYT QRKYEDILFY LPQLSQISLV RYESSSLYRF LLEKASKSMH 
       460        470        480        490        500
FALKLSWLYH SIVEDNSSKY KDLAQRMIQE IEMAVVNCKP LNNECKSFEE 
       510        520        530        540        550
NKQSYLLDLA YPLLFKRKFI LKKIKTNEKL NKIKMYNKCL NNSYNSYTLK 
       560        570        580        590        600
NLHVSNPIEM DTTSFLRNHK NSNDSTLSQG LPNKSSNDDN CNVLKREDHQ 
       610        620        630        640        650
DVINISSEEN EERDINKNLK EEVTTLDDNK ISRENNLQNL QSEKKTPILK 
       660        670        680        690        700
RKNLKQAHTT PCPKLPPCYI INSGSLSIAR AKVKLPSTYS KLGNPLSFSK 
       710        720        730        740        750
FSLPDFNYSY DMIEELQQFF MKQRRCDYFS LLNNFINLLI SVSNLLAAEP 
       760        770        780        790        800
DIDLRNELLR RFIYSLNSWM NMRRCIVACC ENIFAMTGLC IPLESMSSST 
       810        820        830        840        850
FNHDTNNRLS YNNLQILHFN NEECKIFFSK KRAPYLLMFE VADLDEDISH 
       860        870        880        890        900
ISDNIFYTKK SLFFQQDNNN NNNNDNNNNN NNNNNNNNNY NCNNNNYNSD 
       910        920        930        940        950
VQSKEPKNVR EEYSRKSLIL SRNFCCSKNY GYYEENLNTF DYENRLSLED 
       960        970        980        990       1000
KKKKNSKKKK YAKEQEQTNN EKLKDKEKER KKKNIFDLNS LKMDDIYVYN 
      1010       1020       1030       1040       1050
CIVNDLRREN LISFTSKEDE NLALIKKCLG LKMVEEEKNE NDDDDNDDDN 
      1060       1070       1080       1090       1100
DDDNDDDNDD YNEEEEDDNY EKKNFEEEQK GNYNNDNINH NEKKKKVPTA 
      1110       1120       1130       1140       1150
NDNLSSSSFC VKKNYLLNSR SVSMPSYLNN NLEKCDTSSY DNTSNNIKTS 
      1160       1170       1180       1190       1200
IETISNGIDD IQVEKNIEKN ETFEEMKRKN SNNEFIDYNE HMVKLSPYYT 
      1210       1220       1230       1240       1250
TTNHRGKNKN DDTDDNSDDD NINNYNNNNN SGNNNQDNTI SNFPNNILDL 
      1260       1270       1280       1290       1300
SEYFKPENYL NEEFKKKNCK IIKRLLWGEL FEEKKKRIRK VSPYGKLKTW 
      1310       1320       1330       1340       1350
DLKCVIIKGG DDLRQELLAS QLIKQFKIIF ENAGLPLWLR PYEILVTGSN 
      1360       1370       1380       1390       1400
SGIIEYVNDT CSVDSLKRKF GADSISTIFN IVFSDYIFEA KKNFIESHAA 
      1410       1420       1430       1440       1450
YSLISYLLQV KDRHNGNLLL DSDGHLIHID YGFMLTNSPG NVNFETSPFK 
      1460       1470       1480       1490       1500
LTQEYLDIMD GEKSDNYEYF RRLIVSGFLE ARKHSEEIIL FVELMMPALK 
      1510       1520       1530       1540       1550
IPCFANGTQF CIESLKERFM TNLTVDVCIQ RINALIEASI NNFRSVQYDY 

FQRITNGIM                                              

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ