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Protein

MATH and LRR domain-containing protein PFE0570w

Gene

PFE0570w

Organism
Plasmodium falciparum (isolate 3D7)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
MATH and LRR domain-containing protein PFE0570w
Gene namesi
ORF Names:PFE0570w
OrganismiPlasmodium falciparum (isolate 3D7)
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 5

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0511500

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3398 – 3418HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Biotechnological usei

Possible candidate for an effective malaria vaccine as determined by epitope response in sera.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003568301 – 10061MATH and LRR domain-containing protein PFE0570wAdd BLAST10061

Proteomic databases

PRIDEiQ8I3Z1

Expressioni

Developmental stagei

Expressed during the asexual cell-cycle on the cell surface of the host erythrocytes.1 Publication

Keywords - Developmental stagei

Merozoite

Interactioni

Protein-protein interaction databases

BioGridi1208256, 13 interactors
IntActiQ8I3Z1, 10 interactors

Structurei

3D structure databases

ProteinModelPortaliQ8I3Z1
SMRiQ8I3Z1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1328 – 1458MATHPROSITE-ProRule annotationAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili338 – 366Sequence analysisAdd BLAST29
Coiled coili431 – 469Sequence analysisAdd BLAST39
Coiled coili1916 – 1948Sequence analysisAdd BLAST33
Coiled coili2555 – 2580Sequence analysisAdd BLAST26
Coiled coili3977 – 4001Sequence analysisAdd BLAST25
Coiled coili4399 – 4424Sequence analysisAdd BLAST26
Coiled coili5006 – 5046Sequence analysisAdd BLAST41
Coiled coili5486 – 5563Sequence analysisAdd BLAST78
Coiled coili5728 – 5810Sequence analysisAdd BLAST83
Coiled coili5900 – 6022Sequence analysisAdd BLAST123
Coiled coili6719 – 6743Sequence analysisAdd BLAST25
Coiled coili7601 – 7637Sequence analysisAdd BLAST37
Coiled coili7710 – 7813Sequence analysisAdd BLAST104
Coiled coili7934 – 7961Sequence analysisAdd BLAST28
Coiled coili8217 – 8241Sequence analysisAdd BLAST25
Coiled coili8644 – 8697Sequence analysisAdd BLAST54
Coiled coili8882 – 8907Sequence analysisAdd BLAST26
Coiled coili9219 – 9247Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi67 – 10059Asn-richSequence analysisAdd BLAST9993
Compositional biasi440 – 451Lys-richSequence analysisAdd BLAST12
Compositional biasi879 – 1129Lys-richSequence analysisAdd BLAST251
Compositional biasi2152 – 2241Asp-richSequence analysisAdd BLAST90
Compositional biasi3991 – 4068Lys-richSequence analysisAdd BLAST78
Compositional biasi5710 – 6058Lys-richSequence analysisAdd BLAST349
Compositional biasi7584 – 7687Asp-richSequence analysisAdd BLAST104
Compositional biasi7601 – 7704Glu-richSequence analysisAdd BLAST104
Compositional biasi7708 – 8095Lys-richSequence analysisAdd BLAST388
Compositional biasi8285 – 8363Asp-richSequence analysisAdd BLAST79

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ8I3Z1
OMAiVDPAMDV

Family and domain databases

CDDicd00121 MATH, 1 hit
cd02869 PseudoU_synth_RluCD_like, 2 hits
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR002083 MATH/TRAF_dom
IPR020103 PsdUridine_synth_cat_dom_sf
IPR006145 PsdUridine_synth_RsuA/RluD
IPR008974 TRAF-like
SUPFAMiSSF48371 SSF48371, 2 hits
SSF49599 SSF49599, 1 hit
SSF55120 SSF55120, 3 hits
PROSITEiView protein in PROSITE
PS50144 MATH, 1 hit

Sequencei

Sequence statusi: Complete.

Q8I3Z1-1 [UniParc]FASTAAdd to basket
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        10         20         30         40         50
MDCNFFEEDG SSSMNQTNGI SKENVSEKVY SEDDKNTSCY VSYSSHSDDS
60 70 80 90 100
YLDVEYENVH KSRDIENHIN DNNKNMDNYN LGYCNFNDVM IDKNIECINK
110 120 130 140 150
KELNCLKLKK NILNRSENYN NDIVSTEYSD NHTLYKNCSG TDDKNYSNNK
160 170 180 190 200
DDKISDDHKC DKFVDDMDNN PNNHVSNNGD PKKCENLSPD NDTSNSIHKN
210 220 230 240 250
NNTNINEKKN GEKKFIEGHF LSVINKFKRS LKENVIGKKI WNNNNSDITT
260 270 280 290 300
IEPHTLQNED SITDNNKSNK KSDNNNDKKN DDDNNNNNNN NNNNNNNNNN
310 320 330 340 350
NDNHVCTSNN QPNTINKQNN LPSHKINDQN GRTKITPQNV NQKEKEIKNV
360 370 380 390 400
VKEKNNFNRE EKDITNSDDY DENSTDESCS YNPNITSSEN SEEDCYEPSS
410 420 430 440 450
DDKPSNNTSD HININDIRND VPSNDNASSL NVKSAENCNK EKKKKKKKKK
460 470 480 490 500
KELNNDNKDN TLNNETMNDI NMNNKNDNTC FTIQESNKNC KNENFLILGN
510 520 530 540 550
ENEMKTSRIN VPKIEIIKDE EPNRFFDNND LKNKNINDHD NDNDDIDFIK
560 570 580 590 600
MIKDKMKKSI YNNKDNKCIS KKSNINKIEN PVNNNNNNNN NNNNDINIFS
610 620 630 640 650
NLSEQNILKK ESNVCESYEG RKESNNTIHK IHCSKGKKNI MNLNNSSNTS
660 670 680 690 700
SNFLSQHTLD DINKKYNVLS DVNLLKLIAH CSKSKNGEFP SMDDKIIEDF
710 720 730 740 750
INMKKNSIKN EIKKHIIYIC AKCRLEMKLS NNPYLCFECF INEMNAHTGK
760 770 780 790 800
TVRMANGTDF NIKDVKVINS YISKFFVEVD KLKNKFEMDD EEIMLMFSEM
810 820 830 840 850
RKSTLWNSEK NMCKLFFDIF KNYDIIDNNS IFSSNNKTRT DFLKQNYDIK
860 870 880 890 900
IEEWNQNEDE KRLINNIINN EILSPGYIKE LLKFYNFSKM KMKPKTNEQI
910 920 930 940 950
EEIYLKPKSK KVNHYKNIRK KKYTVHKDIC KIRTVCNSTC RINSCNYCSC
960 970 980 990 1000
IFDSIKCRFI LISKMKNTKK LVYEKRINNS TISVEKMHEV KEIKIEQKDI
1010 1020 1030 1040 1050
FIHDDQKNSK DVPPSYNFGN SPIPNEEKPN VNKEGNIRIR NAINIFNKNK
1060 1070 1080 1090 1100
NNNNNNNDKN DKNDKNDKND KNDKNDGKNN NKGNDKNNNR GNDKNNDKKN
1110 1120 1130 1140 1150
NRDNDKNNDK NNDKKNNKDN NNKKKKNGKE QNEDSTESDD ESSVIDDNYI
1160 1170 1180 1190 1200
DDDSCDCDSE SDSIDYDTSF NSESNYDDNS FIDMSDNDNT LNYIKNYETT
1210 1220 1230 1240 1250
YNALDIFMKD IDKINKNREE LNNILPIKKS LDNYVLPNII TQKVLPPVIL
1260 1270 1280 1290 1300
PLNKQMTNLF YELRYRDFFH IEKIDYYKLF TMQKGISNIY MKKFLMNNED
1310 1320 1330 1340 1350
MSFNSITNGI ETYNYTNENI VINHKNNNGK IELYIPNFWR SIKSVNEIKS
1360 1370 1380 1390 1400
LTGNYYDFYY KVLVHPRGNS NDDNYMSAYL EVIKQDFYPS EWVFPNVHFQ
1410 1420 1430 1440 1450
LTVHNFKNRK NSISSASCWS FTNNSLSRGW QKMISHSKIN KVSGFLDESG
1460 1470 1480 1490 1500
GLLIKGKVEI TFKQLWSKSV QYSPKYIWSY MPEKLYAHFQ QEDPLLNFLF
1510 1520 1530 1540 1550
KKSYFKNILH KNEKHNNYNS SINDLKKNDN NKSNNYYINK NSNCDKNKNI
1560 1570 1580 1590 1600
DRMKKMSYYN MNYLYNRYTL DIYNYSLYWS PQLVKSYFGN VDHKKKCNKS
1610 1620 1630 1640 1650
LANNTNNVIQ NDMNKEEKVL DIISDSYSNM HVYDLLIKRK NLNELKKFSK
1660 1670 1680 1690 1700
GGNLQNEQKG DEDVKKEDVK KENVNKEEIK NGNNNNNNDE NENEVDDNTV
1710 1720 1730 1740 1750
STTDYLTLDD RKHVLTLTNY IVPIVESFHD NDNLTILVNT LYNIDLFKII
1760 1770 1780 1790 1800
VLKYNGNLYN RILMKYIKKK RKEKRYKLEY VMKKYGIEKH FTKNEVIQKI
1810 1820 1830 1840 1850
KEYNENKIDN YDDCIKWKNT LIQKLQIISE RIKYLYTYMN DKINNMNNIN
1860 1870 1880 1890 1900
YKSYFQLCNS NEIPNIQFIN VIDIQKEEII INGITRINNY INYLNVWIQN
1910 1920 1930 1940 1950
VNDCINYVTN CGYNFNYLSN LNKVKININD LNNNIVDVNN SIHNIEKEDI
1960 1970 1980 1990 2000
FKSLSYPKDH STTFEGIHNN MSHKETSSIQ NKGKEKSNNN IKSDDNNNNN
2010 2020 2030 2040 2050
DNYCVGDYLE FLEYDFIDNP DELKRIPYRY SSDFKSFHMF EYFRKNNNNV
2060 2070 2080 2090 2100
IVSLQRIFIC MQLYSLVLCA KKKKDHFEKY TSDVNLNELY YNEKDNFHDN
2110 2120 2130 2140 2150
MNKFKGKNNK YNKKQEYYNQ NNYDCGVKNS YSSSLSTAVE TLTANGIKEA
2160 2170 2180 2190 2200
KDDDLNKSSL NKKKCHDKDN NDQPHYVSTN SSNSDDDDDD GDNNNNKNDN
2210 2220 2230 2240 2250
MDDDSYYERN SIFGDNNDDK DDDDDDSYLD NFSDSDGKKN DPSYKYDIEN
2260 2270 2280 2290 2300
NEEMKFYKDL ELRKKNCLYY YRNALFYNGS SMIPCEENKH FTIPLKGIDN
2310 2320 2330 2340 2350
NGANPENFDD GTENMCSFLN MFSKNDNYLN LFKPLIPNIK ILLFSLNKIL
2360 2370 2380 2390 2400
FNKHRCNEPI RKIHEELFKR IVCDVARDKI KLNRKIKKLK KQNNKGDIIN
2410 2420 2430 2440 2450
DLINDLKELR FFEKICYELF KLKSKNYSDD EDSNNRMEES EYSENSNDLS
2460 2470 2480 2490 2500
YDEFDSKISK YPTKVGNEGK KSKDNNNNNN NNMMGDDDNK VNKNEEGNEQ
2510 2520 2530 2540 2550
NESAQIKEGK EKKLRDFIQK EDIRNEDNES YEYYNDQGTE NLDDMNSDEY
2560 2570 2580 2590 2600
MNNNNNNNNN NNNNIKRLDD SYNKLLKNKN INSLIYNLVS KLKMDFYKNY
2610 2620 2630 2640 2650
IICDKDIFKT IGRLCFSEIP YVLFLYMDCY KSLGRGDLVD IPLYLDVFEE
2660 2670 2680 2690 2700
NEEMEDDSKG EKNLVYSIRR NNMRNKGDGS SKEKITYHLY ALVISQNKNP
2710 2720 2730 2740 2750
NNNLFIPSYN KVNDMEFNIG NDCNLNSSSY LILKPQINGP WYQIYKNRIT
2760 2770 2780 2790 2800
QLKQATDFNE WKCHRDFYCS CCIYVSDNYF EMQNHFFLQQ FNIKDINFPL
2810 2820 2830 2840 2850
YVHTLKEFEI EEEDIFEFDR NNKNDDMYSS SVNNGLEENY VDELIYELRK
2860 2870 2880 2890 2900
FSLDKSEKKL NEQKDGNGVP KSSNDKLVSY IEEEKYSSHF KKVFEKNNLY
2910 2920 2930 2940 2950
KLVDDINEKY NVKYYGSSKT KIFSKKKNVP MNIKEGTFPY IKTEHDIIYN
2960 2970 2980 2990 3000
CLQAHHRLMI NVKEELIDDV IKVNNNNNIC YNFNNHHKSA VCIVLNNHNT
3010 3020 3030 3040 3050
LREDKRRHFF DLKNIIKNYE KFDMNNLNIY NSNIKLMKFS DNFSTGLIIT
3060 3070 3080 3090 3100
KNMPLFYSNI TLKNIINVRN NSIIDSDNER KHLIHKIGED HHHNNNSNNN
3110 3120 3130 3140 3150
VEGNISKVYC KKELKGIISS NETNDTNHTN RTNRTNEMKE ENGLSDIRNY
3160 3170 3180 3190 3200
EQNDNITTTN TNDKKLDVVD NISETNDLNL IRKNGDINKC IEKGNGGGKG
3210 3220 3230 3240 3250
RLNVMNNNIQ KCKNKYNTKK ECRNLNILHC NTNNIIINRN DMNYVKYIMQ
3260 3270 3280 3290 3300
LENFLKGMNF NNKFFFNMNN VKDPIRDPFH LEINNVFYNF FEVKMNMNNI
3310 3320 3330 3340 3350
KKNYINNQEK SELHSYYIKT CLNIFKSFFH EYFYLSFINK MEIKKKKKNA
3360 3370 3380 3390 3400
FKNFCIALSD IFFTNLSFKS EEDDDNFEHL QGGIIIYEFY EKRFKKLKLI
3410 3420 3430 3440 3450
LKKIFMYLNI ICMIIKYIKL KKWIFNENFD MHTCKMHDTF FFNFLYFFYN
3460 3470 3480 3490 3500
KYSKNCKNNY IKKLCQKSAV KKKQIINGIK KNMNTVKDED FYFLEFYDKL
3510 3520 3530 3540 3550
FVKREPLMQE HLSNKLDKLL TYCTCIISTN ETQIINPKIY KKKKALFFER
3560 3570 3580 3590 3600
TQHNIDCVFR YFSSSLHDEI LYLSKRRNDF NERKKYKEQD KIASEKEDQI
3610 3620 3630 3640 3650
YSIHGNNMNN QDRMYLYIEE NFNSIEETNP KRMEYFLLNL LKNNEKKRKT
3660 3670 3680 3690 3700
CVLCYCVRRY YMNFLNKLEK KLTHDFIEKQ INFIFDNNYL EITKLYRRTK
3710 3720 3730 3740 3750
NNLLDPNCNC PSLFNYINID TVEACIIYLL QTMWKFYISY ILSIPNELEQ
3760 3770 3780 3790 3800
YYENLAKKHK RKKYKNSKDE KGWNFIKFLK EEKTNNLINK YISFNDDSDV
3810 3820 3830 3840 3850
ISTNDEENVD RSDDSESNDD KKYSKKKQSN LLLSNFDFVD ISSIEKLTSG
3860 3870 3880 3890 3900
NSSSKNSKKN SNNESIQMDN TNNSNSNNNN KNDNNNDNNN DNNNSFCYYC
3910 3920 3930 3940 3950
ADELNVKNGK ILDTNKNIES NDKSYKNQNI QSNEQSVTPN RNIEENKDHE
3960 3970 3980 3990 4000
KKSNNSFYNI NLDILKQDDL FYKCTNEHLG NATAVLNILQ KKLENEELKK
4010 4020 4030 4040 4050
LMKLFHFRGF TEKIPNEECS KKKCIKNKNV HKNKDDVIVS AHKEKNVKTD
4060 4070 4080 4090 4100
SSDDKKKKED NENNNKNKNN IIHNSTNNNV LKENIHNITQ NEYIKNDLKN
4110 4120 4130 4140 4150
ILSKDNLRNE DPSDILENNL ESVFNGTHVD QKFISNFYAN LKIFKDCLDK
4160 4170 4180 4190 4200
NELTKGNNSK DNNNNNNNNN NNNNNKNNMG QENVLMSTIH KVNETMKKYN
4210 4220 4230 4240 4250
INNINEIKSV LIKNGYDIRK CYNGIDLIFL FLSKIKGANV NFINGNNFES
4260 4270 4280 4290 4300
NKNMYEILLS NFKSLNYEKI EKEYYSLDYI LGNFEYIDEN YIEERYASFF
4310 4320 4330 4340 4350
NYMDVIFTTQ NMIDDSDIIT QDIFNPFIDI MNNLFCYGIG LIDNNNNMNS
4360 4370 4380 4390 4400
SSNNNNKINS NNSHSNNKNN NNKNKNNNNS NNNNNNNNSN NNSNNNNSNN
4410 4420 4430 4440 4450
NNNNNNNNNN NNNNVNKEII KLNSLYSFLD NLHKCVGSLL IIDKSYDCKK
4460 4470 4480 4490 4500
ELFSFIQYNS FFWYILYKQY NMFLTYYDMT NHCNFFNIFL FHFFNYTFNF
4510 4520 4530 4540 4550
PMDNFFQLDN KLSFEKEQIV NHLFTKFPFL KEEEKSLFHI IMRFLLQEKN
4560 4570 4580 4590 4600
HFYNYYYSNE LSLFIFNAIM SLNNFYLNMK EPNIFSKDYT KLNDYNFVLN
4610 4620 4630 4640 4650
MKEVYDIQPA VINKKSKCEE SSNKIYNVCK SSNNNEEIKS VENDKNGGNS
4660 4670 4680 4690 4700
YFDNFILNKE NILDILEKKN EKEIYEIGKV FDFHIKNESI YFKKRINMLD
4710 4720 4730 4740 4750
FVMNDYKKEN FVNYSNSDIN NKIFYVAYNY PIININNKNN DLFSIYLRTI
4760 4770 4780 4790 4800
YKCNEHFRNL NHVFFIYSNY FYNFHNLFLF FNKDNDLFNS LFKLRFKIDQ
4810 4820 4830 4840 4850
AKQMDNFYYD MEDKNNNTYM NKEYVQIKKK NENENNITFS NPIGNYKNYE
4860 4870 4880 4890 4900
YAIHNSKSDI FYIFDDIVYD ITESVNMDYY FKGNRAYVNF VKNKMYGDDN
4910 4920 4930 4940 4950
KEDDYIQYDE ISINEANQNK RKQQIDSSNN NNNVVVNNDD NDNDNMCSNN
4960 4970 4980 4990 5000
NYYYNNIYNN DNLCYNRNSI QFDDYMDETI LSELINNKET DGLNADSSNL
5010 5020 5030 5040 5050
GPYNMNNVKN KNNNNNNSNN KRKKNEKNEK IDKIEQFLHE SELEKDIMNI
5060 5070 5080 5090 5100
TFNEKEFLGK DLSFNFYFRS IMYYNKDIIA SNNLEYLMKD KNFITGNVGK
5110 5120 5130 5140 5150
KYFFISLLFN IDYYNVRGMN IGNKVVSNRT MFINKILRDN KGKVLNLKVF
5160 5170 5180 5190 5200
HIYNIFSKII ELYYERKRKG HNMMSLKNSK IASTNGNNNN NNNNNNNNNN
5210 5220 5230 5240 5250
NNSKSNLKDE DNTINLFDYK TDEDFYYKVK MNPSYFFLLY AIKKDYDKRN
5260 5270 5280 5290 5300
KNKLIFMNVN SDLEAYIEDK KDNNIYNRFD LNILLVPISS QIVLSKFNGN
5310 5320 5330 5340 5350
LNMFNDNDYP LITFKYLTST YELICIGIIL CSSKLLLQDY ILNWFFPKLK
5360 5370 5380 5390 5400
ERRLVKDDVD LKIDDIYVYE ESELYCLEKI RKVSCNIKKL LKKYSNTIVI
5410 5420 5430 5440 5450
QLKKTNMNNS NIDKINLKCV EYSKLNKYNF CSKCRNNYIC ICEKIEREQL
5460 5470 5480 5490 5500
RKKVSLIKQE EQLYRYFKIY NNNMNMNNNN SNNNNNNNND DLLNMLNNDK
5510 5520 5530 5540 5550
EAKKILVLME KMKDLKKAQN IKAQEKKINK NINSTNTQNV ENDNNKKLES
5560 5570 5580 5590 5600
KKEKEKLLFN IYETPNFVQE LEAIENSCRS SNSSMLSLSS DNISSYSSDD
5610 5620 5630 5640 5650
NLFVDEIDSG SYTFNNIVIP NMVSVKDEEN ETQEKTNSSD LKKSQKVNII
5660 5670 5680 5690 5700
KKGNGVKNDM EDIMLKEFHK LSKQRISNIY NLQQSVQLSQ ENVNNNNMVL
5710 5720 5730 5740 5750
NFIKAQENMK NKNMIKDAKK DSKKIPVDVL KDKKGKTSNK EELEKEKEKE
5760 5770 5780 5790 5800
EHKLKEQQTV QEDQKVKDNK KIKDNQKVKD NKKIKDNQKV KDNKKIKQDN
5810 5820 5830 5840 5850
IEKTKNDKEE PIQINENTKQ SNIKIVSLTK SQESLTDNKK TNADNEKQLT
5860 5870 5880 5890 5900
VNKIVPKIEN KKTEPAVDVK GKVEKSKLSK DKSVIVPEVK KEIINNSVIM
5910 5920 5930 5940 5950
NNDGSNNENK NKENKNKSSE KSKAKDNNNN KKDNNNNNNN KKDNNNNNNK
5960 5970 5980 5990 6000
KDNNNSNNNN NNNNLSNNGE EDPNDSDSDK DKKKKNKKKD NKNINDDSDD
6010 6020 6030 6040 6050
NNKNKKKLKN NIKNSDDIIN NYFSKNVIEY IEKNDKLENI ATYIYNELIE
6060 6070 6080 6090 6100
ITKKKIKKNV IRLDNLSADN YLTIGEEFLN VMKEILLKIY YKYNEDDYRK
6110 6120 6130 6140 6150
HYLRMNNNEN DNNNNNKISL KKKSETEASN KNVESNDNVD GKLENEYNED
6160 6170 6180 6190 6200
ETYMNKFNLC DDEHVIKFLN LIKRKLIYKI LFPDIQIDTK SKGRNKKNVK
6210 6220 6230 6240 6250
KKKQVDIKYV YDIFKREYIF YDKILIMIQH ILDINIRTNI FLFVYLFAGK
6260 6270 6280 6290 6300
LISFVDFDYI LNNTIFYNDY VYYNKVAFED TFFQEESLEE SNKKYYNMND
6310 6320 6330 6340 6350
SINMPLPDSP TTTSNSNNNN NNNNSNNNNN NNNYDKGEVK GLRTSSEQLL
6360 6370 6380 6390 6400
NSLNNEGNNN KLKEDNVMIN EENNVNEDIE KKKKKKSIEE EGSGDDVLIN
6410 6420 6430 6440 6450
VNMSKIIYIL ILISNKRIMK ELIEEKYREE LNEYYYFEMN KKYYDILCNE
6460 6470 6480 6490 6500
YNKILNENYA KDLSEHYVKD ELFFESLNII ELLNNKEYIS TLTDTNKYIK
6510 6520 6530 6540 6550
DENKKLNKTH VDDNELIINE YEFMNEKNIN KYINIHNIIK FKLNFKIAIK
6560 6570 6580 6590 6600
KINILQDKIF INNNDNISSG ISFYSLIFKY NSNLINTLHT DIMKTTQNNN
6610 6620 6630 6640 6650
MSIPNMTNYN NYLQVSKKDI DKLKGIYNKY VVLNNKPNVL KDMYILNSEI
6660 6670 6680 6690 6700
NTLLSVLYND INYNNMMNNT YNNILGDTHI SAQNGGYLRA GSNNLSNNKM
6710 6720 6730 6740 6750
NNQGGNHINV KRVLTNNLNM NNMNNNNNNN NNNNNNNNNN NNNNNNNNNN
6760 6770 6780 6790 6800
NNNNNNNNNI YINEGGTINM KDLKLNLSKV IGTNPDIQNE INNNSNHDKK
6810 6820 6830 6840 6850
SILKNSSTYS SIYDNNTPTI INKNNNNLKT SVGLNSPTSN RNKKSVTTFD
6860 6870 6880 6890 6900
SKVTLSASYN SNEINNMNED SKLRRLSDQP LSAKSSKIVT PPGNNMNNNT
6910 6920 6930 6940 6950
NNVINNTNNV PNNTNNIINN NVATNKYIKK SKFKRVYNKD IPYICNEGKT
6960 6970 6980 6990 7000
WMVIYKPAYY HCSAYTSHNR YNFLVNINKY SDYFYNILEK ICMKCKIKTK
7010 7020 7030 7040 7050
FMCITCKDME NICSKCENIV SKFCKKCNLL IKKNRDVLKI INSISLNDVV
7060 7070 7080 7090 7100
FSGRVESFHL FMMKSFPHLE TVKKWHKLEC GLCHRIDLET SGSLIIAKTK
7110 7120 7130 7140 7150
EAREFLFDQF RKRNVYKEYI LLCHGRIKKK KGFINKSIQT HEYNNFHSKS
7160 7170 7180 7190 7200
HFSLVVKTGG TDAYTEYNCV KVYKLKRKIE DIIQEVQDGK YNCNSTVKKD
7210 7220 7230 7240 7250
INKEIYCNDY YKFLNNNKKN VNIIQRYVII TNILSNHDNI TKKKDTSNNL
7260 7270 7280 7290 7300
MTQEDYSSFV QRKNSHIITN YFSDSQILED KKKIKKKISS THNNKTLNIK
7310 7320 7330 7340 7350
GINHILHDDT HYNLNGNINS RGSYINKNDF TNNMNNNMNN MNNMNTSTLG
7360 7370 7380 7390 7400
IYTSGAPSIK KEVCHHLCFR CNSISEDYFL TDPKEIENYT KEFTLCNVKI
7410 7420 7430 7440 7450
HTGRTHQIRV HMRHIGHPLV SDKKYLNPSL SNLDKFWCFR MFLHSLILEF
7460 7470 7480 7490 7500
NNPDYYFFNL NDDMKKKKKM YSSNLYRMPD RTVKAICPLA GDLQTVLDNE
7510 7520 7530 7540 7550
LEISESLEDE NSYINRILKM NINDKRNEAM KNARPIIEDD KFVKHASMDS
7560 7570 7580 7590 7600
SKIIHSAREE TNDKEKISTQ AKIIEVGKKL TTKDEDMLHS KKTDVIQHGD
7610 7620 7630 7640 7650
EEEDDEEDDE EDDEEDEEEE EEDEDEEDVE DVEDIEDVED VEDIEDNYVD
7660 7670 7680 7690 7700
DDQYEDNYDD DNDNDDDDEY DHDYDEHINE EEQEDDDKKN NVNINDSYEE
7710 7720 7730 7740 7750
GEEEGDGKLN TKIKKDKKST ENNISVVEEK VKSIDINKEE DFPDLLSNSK
7760 7770 7780 7790 7800
KKNHKDKRNA SKNKNKNKDI LKKNENNIND EKEKKSSNVI TKNNKEQNEI
7810 7820 7830 7840 7850
IDNKNEHVDN KNEIIDNKNE IIVNKNEIIV NKNEIIVNKN EIIDNKNEHI
7860 7870 7880 7890 7900
DNKNLLNGSL DEYNNFKEKN LLSKENLKIN DTTTITTSVE IPNDEHIKKI
7910 7920 7930 7940 7950
LLKKPTNKIL RKLNYDDFFT NKKKKDMNKE NMKKTDEQKI KEEIKQTQDE
7960 7970 7980 7990 8000
EDTYLDLIDN EIKKRLRTNF NLLVKEAKIV INNIIRNSFV FKILFYFFKL
8010 8020 8030 8040 8050
KKTLLYLLKC FGIEQIKKEK KVYVEMNILD EFVNNMNENK ENMPIDFLYE
8060 8070 8080 8090 8100
LIHSITYFYK NMHVKKTRKK KEIIIYTLKK HLKNIKSNSN ISKTKRSLIF
8110 8120 8130 8140 8150
QRFYNILFNL NYALNKYGLK TNENLKNQIM KKSKNVYLKI TNVFTIIMNI
8160 8170 8180 8190 8200
LNSKVYMKDI HIKKLMENKA VFSLNTIEQF LLLHKINNET GGEGTNNDKE
8210 8220 8230 8240 8250
KKRQTKVSNT QGYNKDNINN KEKETNKNEE QQQGEAEGKR EGEGEEGEGG
8260 8270 8280 8290 8300
EEEECNYLIE QINKIFFKVD KNNEHMLNGV LLENDDDYLD EEGKVSKKKM
8310 8320 8330 8340 8350
KKKKLLNDKE HEKDNEDNDE DNDEDDDDED DDEDDEDDDD DDDDDDDDDD
8360 8370 8380 8390 8400
DDDYDEDYDE DYDEKLVENK KNERSNIIMS KENMNKLNMQ PKNTNNRSSS
8410 8420 8430 8440 8450
SNTIDMKKKI YEKNCMKEKE YRTHDLITNE SIMYKNNEIY DKEKYRRNQE
8460 8470 8480 8490 8500
NINHMSSNYM DKNINHHHEY DNMKKKNYSN NNIYNNNSSN KVSMDEEKRK
8510 8520 8530 8540 8550
NLDNNTYPYP MYENVKEIEK NKVQQNLFHI SKENNNNNND STNNNSVYDY
8560 8570 8580 8590 8600
NMSNSNYGSK MGSNNINDST NYYNMREKNI YNILCNNDSN NYVLFNSNEK
8610 8620 8630 8640 8650
YSMNNKISNS ILSNMIMNKQ DNNNININQN NNNNNNNNMN EGGSETLYSS
8660 8670 8680 8690 8700
FTKEIEKLKK EVRKCEESYD KEMVEIQNTK KEIKYLRENN KNDELNNIFS
8710 8720 8730 8740 8750
ELNLENISKY LLSAYEKYGL NVFIKVLVYK NDLGHINDHI KKQDDVNMEF
8760 8770 8780 8790 8800
FINISVDKIF DYLLLKKNII TMVNIKKLKE KFIQGQKIYE LVKNETNKMI
8810 8820 8830 8840 8850
IENIKEYNFI FILWKHNNMN DLYERKQVIF NFIIKIIDKI IPKYIINEYI
8860 8870 8880 8890 8900
IIRKNEIYEI MINSLNKKNE YEKKNKDISS SQYLEKENTY NNLYKKIKDE
8910 8920 8930 8940 8950
KRIVDNYSIE MHAEKNITNP IYMSQREDNS TPNSKKNCSN TNHIMSINHS
8960 8970 8980 8990 9000
NMNNTKNTNN HNNNNNNNNY VVNHTTHSTS FYYLHNEKPS NVNTDNQKEI
9010 9020 9030 9040 9050
KDDNVHMKFQ SLPENIRIGV FKNDVNKFYE IYKMMNAGND LNSLMYKNSG
9060 9070 9080 9090 9100
HIKNKVNNEP YSNNYKRNTF CTNDINFAAS AQQSFMNKNV INSMNNNMVS
9110 9120 9130 9140 9150
SNNMISSNNI ISNNNMISSN NMISSNNMIN SNNMISSNNM ISNNMMNNKM
9160 9170 9180 9190 9200
NSSNVQIDTE KTRTMNNLQD QFLNLQKNGS HIYLRNTKDS KNSDIFTFKN
9210 9220 9230 9240 9250
NVRSPSQHIT LNEGKENGID MKKKIEQEED KKKIINNNNN NINSNNNINS
9260 9270 9280 9290 9300
NNNINSNNNM NDEDLIKKEI NMNTNDYEEN EKRSSQNKTN YFDNIINNSY
9310 9320 9330 9340 9350
INNKMNNFMI EKKEELNNDM INTFTNKREI NIQTEKAKEQ NIKEPYEVKE
9360 9370 9380 9390 9400
TNHNKGIIHM YYDNEKDINN ITSASGNRHN NIERDKNNIQ TNKTSNNFVK
9410 9420 9430 9440 9450
SFKNTISEMF YKKKLNKNTE IKDEPNQNND TMIYNNLQDM SKKVDEYNEN
9460 9470 9480 9490 9500
KNYNHNIVHN NALKSNQMDN EEKKKIELPH NNNNNNNNSN ERKDLLNNPM
9510 9520 9530 9540 9550
SVNMQNAQNV QNTNRSHEYL INSNISLPNF VDENTCSNLK EKQFESFEKN
9560 9570 9580 9590 9600
QMDMTNPNMM MFNIMLGNNL DGIIPNYMEE KHNKNMNKNV NNKNSVSLSS
9610 9620 9630 9640 9650
SMINNGNVIN NRMHTKTINN NSNTCVPNIK YPNFFINKNN IPYTNENNKS
9660 9670 9680 9690 9700
LSESNLMNLV CELNNIEKVE NLSMQNNLNN NINNKRSTLS QMNLLNMENT
9710 9720 9730 9740 9750
KGNEQHMRTD LHHNINNNIF LSNNLCDNKI VNQMFLKKYY NSNFVHYDEE
9760 9770 9780 9790 9800
NEEKNKLGTI PRHNTTTTNN NNNDNNNNSN NNMHLFYNFN GNTPSDINNS
9810 9820 9830 9840 9850
YCQQKKIMSS SIIMNNKENN NLHFLNNTYD INGSYATSSI INNNMNRNNS
9860 9870 9880 9890 9900
NSVNSNYLNK TFSIMDPRNN INEYEEKQKI IINRIKQQNI SNTSGNMKNS
9910 9920 9930 9940 9950
SNIRSSSNIR SSNNIKSSSN IKSSSNINAN NNILYQLIDE NILKNTLSNN
9960 9970 9980 9990 10000
NPFNEIKNNT QKTNMDFGLN QLSMYMQNNV TSNLKNNSIT NETHNNNDNM
10010 10020 10030 10040 10050
KTNHNNNNNN NNNNNNNNNN NTSGYPINYL IFQQNQNHSD TNNNNNNNNK
10060
NNSNNNNNNI Y
Length:10,061
Mass (Da):1,187,585
Last modified:March 1, 2003 - v1
Checksum:iF13CE7E4FE86F3DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA Translation: CAD51479.1
RefSeqiXP_001351672.1, XM_001351636.1

Genome annotation databases

EnsemblProtistsiCAD51479; CAD51479; PF3D7_0511500
GeneDBiPF3D7_0511500.1:pep
GeneIDi812939
KEGGipfa:PF3D7_0511500

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844504 Genomic DNA Translation: CAD51479.1
RefSeqiXP_001351672.1, XM_001351636.1

3D structure databases

ProteinModelPortaliQ8I3Z1
SMRiQ8I3Z1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi1208256, 13 interactors
IntActiQ8I3Z1, 10 interactors

Proteomic databases

PRIDEiQ8I3Z1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAD51479; CAD51479; PF3D7_0511500
GeneDBiPF3D7_0511500.1:pep
GeneIDi812939
KEGGipfa:PF3D7_0511500

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0511500

Phylogenomic databases

InParanoidiQ8I3Z1
OMAiVDPAMDV

Family and domain databases

CDDicd00121 MATH, 1 hit
cd02869 PseudoU_synth_RluCD_like, 2 hits
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR002083 MATH/TRAF_dom
IPR020103 PsdUridine_synth_cat_dom_sf
IPR006145 PsdUridine_synth_RsuA/RluD
IPR008974 TRAF-like
SUPFAMiSSF48371 SSF48371, 2 hits
SSF49599 SSF49599, 1 hit
SSF55120 SSF55120, 3 hits
PROSITEiView protein in PROSITE
PS50144 MATH, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMLRR1_PLAF7
AccessioniPrimary (citable) accession number: Q8I3Z1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 16, 2008
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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