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Protein
Submitted name:

N-glycosylase/DNA lyase, putative

Gene

PF3D7_0917100

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseImported, Hydrolase, LyaseImported

Enzyme and pathway databases

ReactomeiR-PFA-110329 Cleavage of the damaged pyrimidine
R-PFA-110331 Cleavage of the damaged purine
R-PFA-110357 Displacement of DNA glycosylase by APEX1

Names & Taxonomyi

Protein namesi
Submitted name:
N-glycosylase/DNA lyase, putativeImported (EC:3.2.2.-Imported)
Gene namesi
ORF Names:PF3D7_0917100Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0917100

Structurei

3D structure databases

ProteinModelPortaliQ8I2Y2
SMRiQ8I2Y2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini523 – 683ENDO3cInterPro annotationAdd BLAST161

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili106 – 126Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000282907
InParanoidiQ8I2Y2

Family and domain databases

CDDicd00056 ENDO3c, 1 hit
Gene3Di1.10.1670.10, 1 hit
InterProiView protein in InterPro
IPR011257 DNA_glycosylase
IPR003265 HhH-GPD_domain
IPR023170 HTH_base_excis_C
IPR012904 OGG_N
PfamiView protein in Pfam
PF00730 HhH-GPD, 1 hit
PF07934 OGG_N, 1 hit
SMARTiView protein in SMART
SM00478 ENDO3c, 1 hit
SUPFAMiSSF48150 SSF48150, 3 hits

Sequencei

Sequence statusi: Complete.

Q8I2Y2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNIYNHVLLI ITLKNIYTCK YINKVIQNNI SKFILYKEKK NISELNHNIN
60 70 80 90 100
KKYNFIIKKK NCNKIQERKK KRKRYIYSEK IKNGYPNFIT LNFSYINNYN
110 120 130 140 150
MIKKKNKVLS ERLSNKMRNV KRIRDKVKLH SLNEENKMKN VYSNVTNNSP
160 170 180 190 200
IIIKNYEKRW IKLDASTNDL KLKYCLLIGQ EFCFNEVEKN MYIGLLNIKK
210 220 230 240 250
IYLFKETEKD IFYQCLYDDD NDCDNYNDSN NNNVTCTGYS NKDDKNILKK
260 270 280 290 300
RKSNNHHNEV YNFFNLHFPL NENIEIWKKK DQRMKEITNK ITGLRILKTD
310 320 330 340 350
PVESFFSFLC STNNNIPRIT LMIDSLRRRY GKFIATVVFK NGDIIIKRDD
360 370 380 390 400
QNVDGNNMIK LKHQDDSNEH NEYSINIKGE IKNGEGKIKN GECKIKNGEG
410 420 430 440 450
KIKNGECKIK NGEGRIKNGE GKIKNGECKI KNGVSQIKDT RVRIKNERDI
460 470 480 490 500
TNNKSCRVKK EMLDTYNADN ELGQGNDIND NVNIYNDTLS VTKEDKRNKE
510 520 530 540 550
QNKMFNILYK NEVNKIEKKD VEMLSKDNKI FYESLKTTLK DERNQKTFHF
560 570 580 590 600
YEFPKIQVLS KLKEDDLRSL GFGYRSNYVI ESAKMLVNMG EEEWIENLKN
610 620 630 640 650
EEKTKTCIDK LIQFPGIGLK VANCICLFGL NKYDCIPIDT HIYDIIYKYY
660 670 680 690 700
NNFIEPLNKS NKKNKTIKNV NDNNNNNNVH KKNIQNNLLS NKTNIITNKK
710 720 730 740 750
HINKKLLSTT IKKKKTLTNS LYLILYTKLR NLFGPNCGWA QTILFASELK

KFSHIFE
Length:757
Mass (Da):89,361
Last modified:June 8, 2016 - v2
Checksum:i99A81B188FF2DCD0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844508 Genomic DNA Translation: CAD51853.2
RefSeqiXP_001352042.1, XM_001352006.1

Genome annotation databases

EnsemblProtistsiCAD51853; CAD51853; PF3D7_0917100
GeneDBiPF3D7_0917100.1:pep
GeneIDi813447

Similar proteinsi

Entry informationi

Entry nameiQ8I2Y2_PLAF7
AccessioniPrimary (citable) accession number: Q8I2Y2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: June 8, 2016
Last modified: June 20, 2018
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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