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Entry version 145 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Coatomer subunit gamma

Gene

gammaCOP

Organism
Drosophila melanogaster (Fruit fly)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets. Involved in the expansion of luminal extracellular matrices and apical membrane during tubulogenesis. Required in the tracheal epithelium for luminal protein secretion and diametric tube growth. In salivary glands, required for deposition of O-glycans and luminal extracellular matrix assembly. Required for epidermal morphogenesis and cuticle development.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-DME-6807878, COPI-mediated anterograde transport
R-DME-6811434, COPI-dependent Golgi-to-ER retrograde traffic

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coatomer subunit gammaBy similarityImported
Alternative name(s):
Gamma-coat proteinBy similarity
Short name:
Gamma-COPBy similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gammaCOPImported
Synonyms:copgImported, gamma-Cop
ORF Names:CG1528Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0028968, gammaCOP

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Narrow tracheal tubes and thin salivary glands with reduced tube diameter and impaired tube elongation. Fails to complete dorsal closure. Fails to efficiently secrete luminal components and assemble the luminal chitinous matrix during tracheal tube expansion. In salivary glands, fails in the luminal deposition and assembly of a distinct, transient intraluminal matrix. Disrupted endoplasmic reticulum and Golgi in embryos. Null mutants die late in embryogenesis with a poorly differentiated cuticle and denticle. Defects in cell rearrangements, in branch elongation, in tube dilation and tube fusion.2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004053271 – 883Coatomer subunit gammaAdd BLAST883

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8I0G5

PRoteomics IDEntifications database

More...
PRIDEi
Q8I0G5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in ovary, testis, testis tip, young spermatocytes, germ cells and follicle cells. Up-regulated expression within centrally to posteriorly located germarial cysts and in migrating follicle cells. Widespread expression in imaginal disks including eye-antennal disk, wing disk, third leg and haltere disk.1 Publication

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Expressed during spermatogenesis and at later stages of oogenesis. During embryonic and larval development, expressed ubiquitously. Starting at stage 10 embryos and lasting until the end of embryonic development, strongly expressed in the salivary glands and in cells of the presumptive proventriculus. Maternal expression abundant in early embryos. Zygotic expression commences in the epidermis and salivary glands from stage 11, initiates in the trachea at stage 13, and at early stage 15 is also detected in the foregut and hindgut tubes.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0028968, Expressed in spermathecum and 38 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8I0G5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8I0G5, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
68560, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q8I0G5, 27 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0085155

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati69 – 106HEAT 1Add BLAST38
Repeati292 – 329HEAT 2Add BLAST38
Repeati331 – 364HEAT 3Add BLAST34
Repeati365 – 401HEAT 4Add BLAST37
Repeati404 – 439HEAT 5Add BLAST36
Repeati476 – 513HEAT 6Add BLAST38

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the COPG family.Sequence analysis

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1078, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000016313

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8I0G5

KEGG Orthology (KO)

More...
KOi
K17267

Identification of Orthologs from Complete Genome Data

More...
OMAi
PVNARKC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8I0G5

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR002553, Clathrin/coatomer_adapt-like_N
IPR013041, Clathrin_app_Ig-like_sf
IPR009028, Coatomer/calthrin_app_sub_C
IPR032154, Coatomer_g_Cpla
IPR017106, Coatomer_gsu
IPR013040, Coatomer_gsu_app_Ig-like_dom
IPR037067, Coatomer_gsu_app_sf
IPR012295, TBP_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10261, PTHR10261, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01602, Adaptin_N, 1 hit
PF16381, Coatomer_g_Cpla, 1 hit
PF08752, COP-gamma_platf, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037093, Coatomer_gamma_subunit, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit
SSF49348, SSF49348, 1 hit
SSF55711, SSF55711, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform B2 Publications (identifier: Q8I0G5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNYFSLTSHK KHRGHPSAGP SNAYQNLEKT SVLQETRTFN ETPVNPRKCI
60 70 80 90 100
HILTKILYLI NQGEQLVARE ATDCFFAMTK LFQSKDVVLR RMVYLGIKEL
110 120 130 140 150
SSIAEDVIIV TSSLTKDMTG KEDLYRAAAI RALCSITDNT MLQAVERYMK
160 170 180 190 200
QCIVDKNAAV SCAALVSSLR LANTAGDVVK RWANEAQEAL NSDNIMVQYH
210 220 230 240 250
ALGLLYHIRK SDRLAVSKLV NKLTRGSLKS PYAVCMLIRI ACKLIEEEDI
260 270 280 290 300
PSEELSDSPL FTFIESCLRH KSEMVIYEAA HAIVNLKNTN PRMLSPAFSI
310 320 330 340 350
LQLFCSSPKA TLRFAAVRTL NKVAMTHPAA VTTCNLDLEG LITDSNRSVA
360 370 380 390 400
TLAITTLLKT GAESSVERLM KQISTFVAEI SDEFKVVVVQ AICALCTKYP
410 420 430 440 450
RKHTVLMNFL SGMLREEGGL EYKTSIVDTI ITIIEENADA KESGLSHLCE
460 470 480 490 500
FIEDCEHVSL AVRILHLLGK EGPFAATPSK YIRFIYNRVI LESPIVRAAA
510 520 530 540 550
VTAMAQFGAS CPALLSNILV LLGRCQMDPD DEVRDRATYY LSILNSERPE
560 570 580 590 600
LYKNYIIERE NCSLALLEKS LVEHLNGDVD TRFDISIVPK AAIVKPVIAN
610 620 630 640 650
DVMLVTSSAP RPPKITREEE SAARLAQLPG IQVLGPIHRS TAPIQLTESE
660 670 680 690 700
TEYTVQCIKH IFGQHVVFQF DCLNTLSDQI LENVRVELTL PEGFTTRAVI
710 720 730 740 750
PCPKLPYNDL QTTFVIVEFP PDAANSIATF GATLRFVVKD CDPNTGEPES
760 770 780 790 800
EEGYDDEYML EDLELTVADQ IQKTRKNNFQ VSWDAADSEE WLQAEDTFVL
810 820 830 840 850
SAVTTLQDAV NTIVKILGLG AANLSENVPE GTHLHTLLCS GTFRGGAEIL
860 870 880
VRAKLALSEG VTLNLTVRST DQDVAELITA AIG
Length:883
Mass (Da):97,690
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7C610B0F7A39692F
GO
Isoform A2 Publications (identifier: Q8I0G5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-17: NYFSLTSHKKHRGHPS → GSFRREKDDEED

Show »
Length:879
Mass (Da):97,277
Checksum:i2D306F2ACAE8B055
GO
Isoform C2 Publications (identifier: Q8I0G5-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2-17: NYFSLTSHKKHRGHPS → GSFRREKDDEED
     18-18: Missing.

Show »
Length:878
Mass (Da):97,206
Checksum:iCD358D5D6AA1B423
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4KHL2A0A0B4KHL2_DROME
Coatomer subunit gamma
gammaCOP 02, 0573, 573.02, anon-WO0118547.334, copg
897Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti280A → V in AAF05719 (PubMed:11018518).Curated1
Sequence conflicti546S → W in AAM29550 (PubMed:12537569).Curated1
Sequence conflicti724A → T in AAM29550 (PubMed:12537569).Curated1
Sequence conflicti729T → A in AAM29550 (PubMed:12537569).Curated1
Sequence conflicti771I → V in AAM29550 (PubMed:12537569).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0406722 – 17NYFSL…RGHPS → GSFRREKDDEED in isoform A and isoform C. 3 PublicationsAdd BLAST16
Alternative sequenceiVSP_04067318Missing in isoform C. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF191563 mRNA Translation: AAF05719.1
AE014297 Genomic DNA Translation: AAN14275.1
AE014297 Genomic DNA Translation: AAF57160.1
AE014297 Genomic DNA Translation: ACZ95077.1
AY113545 mRNA Translation: AAM29550.1
BT001628 mRNA Translation: AAN71383.1

NCBI Reference Sequences

More...
RefSeqi
NP_001163784.1, NM_001170313.1 [Q8I0G5-3]
NP_524608.1, NM_079869.3 [Q8I0G5-2]
NP_733432.1, NM_170553.2 [Q8I0G5-1]

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0085793; FBpp0085154; FBgn0028968 [Q8I0G5-2]
FBtr0085794; FBpp0085155; FBgn0028968 [Q8I0G5-1]
FBtr0301290; FBpp0290505; FBgn0028968 [Q8I0G5-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
43717

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG1528

UCSC genome browser

More...
UCSCi
CG1528-RA, d. melanogaster
CG1528-RB, d. melanogaster [Q8I0G5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF191563 mRNA Translation: AAF05719.1
AE014297 Genomic DNA Translation: AAN14275.1
AE014297 Genomic DNA Translation: AAF57160.1
AE014297 Genomic DNA Translation: ACZ95077.1
AY113545 mRNA Translation: AAM29550.1
BT001628 mRNA Translation: AAN71383.1
RefSeqiNP_001163784.1, NM_001170313.1 [Q8I0G5-3]
NP_524608.1, NM_079869.3 [Q8I0G5-2]
NP_733432.1, NM_170553.2 [Q8I0G5-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi68560, 6 interactors
IntActiQ8I0G5, 27 interactors
STRINGi7227.FBpp0085155

Proteomic databases

PaxDbiQ8I0G5
PRIDEiQ8I0G5

Genome annotation databases

EnsemblMetazoaiFBtr0085793; FBpp0085154; FBgn0028968 [Q8I0G5-2]
FBtr0085794; FBpp0085155; FBgn0028968 [Q8I0G5-1]
FBtr0301290; FBpp0290505; FBgn0028968 [Q8I0G5-3]
GeneIDi43717
KEGGidme:Dmel_CG1528
UCSCiCG1528-RA, d. melanogaster
CG1528-RB, d. melanogaster [Q8I0G5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
43717
FlyBaseiFBgn0028968, gammaCOP

Phylogenomic databases

eggNOGiKOG1078, Eukaryota
GeneTreeiENSGT00390000016313
InParanoidiQ8I0G5
KOiK17267
OMAiPVNARKC
PhylomeDBiQ8I0G5

Enzyme and pathway databases

ReactomeiR-DME-6807878, COPI-mediated anterograde transport
R-DME-6811434, COPI-dependent Golgi-to-ER retrograde traffic

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
43717, 1 hit in 5 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
43717

Protein Ontology

More...
PROi
PR:Q8I0G5

Gene expression databases

BgeeiFBgn0028968, Expressed in spermathecum and 38 other tissues
ExpressionAtlasiQ8I0G5, baseline and differential
GenevisibleiQ8I0G5, DM

Family and domain databases

Gene3Di1.25.10.10, 1 hit
2.60.40.1480, 1 hit
3.30.310.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR002553, Clathrin/coatomer_adapt-like_N
IPR013041, Clathrin_app_Ig-like_sf
IPR009028, Coatomer/calthrin_app_sub_C
IPR032154, Coatomer_g_Cpla
IPR017106, Coatomer_gsu
IPR013040, Coatomer_gsu_app_Ig-like_dom
IPR037067, Coatomer_gsu_app_sf
IPR012295, TBP_dom_sf
PANTHERiPTHR10261, PTHR10261, 1 hit
PfamiView protein in Pfam
PF01602, Adaptin_N, 1 hit
PF16381, Coatomer_g_Cpla, 1 hit
PF08752, COP-gamma_platf, 1 hit
PIRSFiPIRSF037093, Coatomer_gamma_subunit, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit
SSF49348, SSF49348, 1 hit
SSF55711, SSF55711, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOPG_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8I0G5
Secondary accession number(s): E1JJ29
, Q8MYW4, Q9U677, Q9V9W9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programDrosophila annotation project

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Drosophila
    Drosophila: entries, gene names and cross-references to FlyBase
  2. SIMILARITY comments
    Index of protein domains and families
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