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Protein
Submitted name:

Tumor necrosis factor

Gene
N/A
Organism
Pongo pygmaeus (Bornean orangutan)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Tumor necrosis factorImported
OrganismiPongo pygmaeus (Bornean orangutan)Imported
Taxonomic identifieri9600 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 144TNF_2InterPro annotationAdd BLAST88

Sequence similaritiesi

Belongs to the tumor necrosis factor family.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000048729
HOVERGENiHBG012516

Family and domain databases

Gene3Di2.60.120.40, 1 hit
InterProiView protein in InterPro
IPR006053 TNF
IPR002959 TNF_alpha
IPR021184 TNF_CS
IPR006052 TNF_dom
IPR008983 Tumour_necrosis_fac-like_dom
PANTHERiPTHR11471:SF23 PTHR11471:SF23, 1 hit
PfamiView protein in Pfam
PF00229 TNF, 1 hit
PRINTSiPR01234 TNECROSISFCT
PR01235 TNFALPHA
SMARTiView protein in SMART
SM00207 TNF, 1 hit
SUPFAMiSSF49842 SSF49842, 1 hit
PROSITEiView protein in PROSITE
PS00251 TNF_1, 1 hit
PS50049 TNF_2, 1 hit

Sequencei

Sequence statusi: Fragment.

Q8HZD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LSLVSFLIVA GATTLFCLLH FGVIGPQREE FPKDLSLISP LAQAVRSSSR
60 70 80 90 100
TPSBKPVAHV VANPQAEGQL QWLNRRANAL LANGVELRDN QLVVPSEGLY
110 120 130 140 150
LIYSQVLFKG QGCPSTHVLL THTISRIAVS YQTKVNLLSA IKSPCQRETT

EGAEA
Length:155
Mass (Da):16,790
Last modified:March 1, 2003 - v1
Checksum:iD561099968693862
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei155Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY091966 Genomic DNA Translation: AAM76584.1

Similar proteinsi

Entry informationi

Entry nameiQ8HZD7_PONPY
AccessioniPrimary (citable) accession number: Q8HZD7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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