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Protein

NADH-ubiquinone oxidoreductase chain 4

Gene

nad4

Organism
Thrips imaginis (Plague thrips)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation, UbiquinoneUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase chain 4UniRule annotation (EC:1.6.5.3UniRule annotation)
Gene namesi
Name:nad4Imported
Encoded oniMitochondrionImported
OrganismiThrips imaginis (Plague thrips)Imported
Taxonomic identifieri159957 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraThysanopteraTerebrantiaThripoideaThripidaeThrips

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 39HelicalSequence analysisAdd BLAST28
Transmembranei59 – 82HelicalSequence analysisAdd BLAST24
Transmembranei89 – 107HelicalSequence analysisAdd BLAST19
Transmembranei113 – 132HelicalSequence analysisAdd BLAST20
Transmembranei144 – 162HelicalSequence analysisAdd BLAST19
Transmembranei182 – 204HelicalSequence analysisAdd BLAST23
Transmembranei216 – 235HelicalSequence analysisAdd BLAST20
Transmembranei247 – 265HelicalSequence analysisAdd BLAST19
Transmembranei272 – 294HelicalSequence analysisAdd BLAST23
Transmembranei300 – 321HelicalSequence analysisAdd BLAST22
Transmembranei342 – 360HelicalSequence analysisAdd BLAST19
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Transmembranei419 – 436HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane, MitochondrionUniRule annotationImported

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 389Proton_antipo_MInterPro annotationAdd BLAST278

Sequence similaritiesi

Belongs to the complex I subunit 4 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR003918 NADH_UbQ_OxRdtase
IPR001750 ND/Mrp_mem
PANTHERiPTHR43507 PTHR43507, 1 hit
PfamiView protein in Pfam
PF00361 Proton_antipo_M, 1 hit
PRINTSiPR01437 NUOXDRDTASE4

Sequencei

Sequence statusi: Complete.

Q8HQ09-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTYQYFSNSF FFFVLFFGVL NMSSWWVFLF FLMYIYPFLH CMNFSLGFFS
60 70 80 90 100
KNYYICLDFF SFLMLILTFW VVFLSIISSL MIKNLKFSYS FILMFFSLFI
110 120 130 140 150
FLLTFFIVNN FFFFFFFESS LIPTLAIIVG WGNKVERIKS GYYLFFYTLF
160 170 180 190 200
ASMPLLLSLF FLKKTNFSLS FSFFEINKAL VLVYIFLVFS FLVKMPMFLV
210 220 230 240 250
HSWLPKAHVE APLSGSMILA GVLLKMGGYG LYRLFSLYKM FLSYNLVWTY
260 270 280 290 300
ISIWGGLVSS MICLRQVDLK SIIAYSSVSH MSLVIIGLLL FSFSSLLGSL
310 320 330 340 350
MLMVAHGLCS SGLFFLANVL YERSGSRSIF LNKGLMSMFP SLSIWRFIFC
360 370 380 390 400
SINMACPPSL NLISEIFLLN GLVSWSFLFV FFLMILSFLG GVYNLFLFSF
410 420 430 440
CNHGSIFSSI FFFNSCYLIE YYILFMHFFP IFMFFLKLDF FF
Length:442
Mass (Da):51,868
Last modified:March 1, 2003 - v1
Checksum:i10C97E03448E5C5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335993 Genomic DNA Translation: AAN64179.1
RefSeqiNP_739608.1, NC_004371.1

Genome annotation databases

GeneIDi805641

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF335993 Genomic DNA Translation: AAN64179.1
RefSeqiNP_739608.1, NC_004371.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi805641

Organism-specific databases

CTDi4538

Family and domain databases

InterProiView protein in InterPro
IPR003918 NADH_UbQ_OxRdtase
IPR001750 ND/Mrp_mem
PANTHERiPTHR43507 PTHR43507, 1 hit
PfamiView protein in Pfam
PF00361 Proton_antipo_M, 1 hit
PRINTSiPR01437 NUOXDRDTASE4
ProtoNetiSearch...

Entry informationi

Entry nameiQ8HQ09_THRIM
AccessioniPrimary (citable) accession number: Q8HQ09
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 7, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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