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Entry version 119 (02 Jun 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Inorganic phosphate transporter 1-6

Gene

PHT1-6

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

High-affinity transporter for external inorganic phosphate (Pi). Probably involved in Pi uptake, translocation and internal transport throughout the plant.

1 Publication

Miscellaneous

Although related to the sugar transporter family, it does not transport sugars.

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

Measured in yeast cells deficient in Pi uptake.
  1. KM=97 µM for inorganic phosphate (Pi)1 Publication

    pH dependencei

    Optimum pH is 6.0.1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Biological processPhosphate transport, Symport, Transport

    Protein family/group databases

    Transport Classification Database

    More...
    TCDBi
    2.A.1.9.5, the major facilitator superfamily (mfs)

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Inorganic phosphate transporter 1-6
    Short name:
    OsPT6
    Short name:
    OsPht1;6
    Alternative name(s):
    H(+)/Pi cotransporter
    OsLPT1
    OsLPT6:1
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:PHT1-6
    Synonyms:PT6
    Ordered Locus Names:Os08g0564000, LOC_Os08g45000
    ORF Names:P0543D10.41, P0705A05.110
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8
    • UP000000763 Componenti: Chromosome 8

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 29CytoplasmicSequence analysisAdd BLAST29
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei30 – 50HelicalSequence analysisAdd BLAST21
    Topological domaini51 – 75ExtracellularSequence analysisAdd BLAST25
    Transmembranei76 – 96HelicalSequence analysisAdd BLAST21
    Topological domaini97 – 104CytoplasmicSequence analysis8
    Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
    Topological domaini126 – 127ExtracellularSequence analysis2
    Transmembranei128 – 148HelicalSequence analysisAdd BLAST21
    Topological domaini149 – 168CytoplasmicSequence analysisAdd BLAST20
    Transmembranei169 – 189HelicalSequence analysisAdd BLAST21
    Topological domaini190 – 216ExtracellularSequence analysisAdd BLAST27
    Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
    Topological domaini238 – 294CytoplasmicSequence analysisAdd BLAST57
    Transmembranei295 – 315HelicalSequence analysisAdd BLAST21
    Topological domaini316 – 350ExtracellularSequence analysisAdd BLAST35
    Transmembranei351 – 371HelicalSequence analysisAdd BLAST21
    Topological domaini372 – 375CytoplasmicSequence analysis4
    Transmembranei376 – 396HelicalSequence analysisAdd BLAST21
    Topological domaini397 – 405ExtracellularSequence analysis9
    Transmembranei406 – 426HelicalSequence analysisAdd BLAST21
    Topological domaini427 – 445CytoplasmicSequence analysisAdd BLAST19
    Transmembranei446 – 466HelicalSequence analysisAdd BLAST21
    Topological domaini467 – 486ExtracellularSequence analysisAdd BLAST20
    Transmembranei487 – 507HelicalSequence analysisAdd BLAST21
    Topological domaini508 – 534CytoplasmicSequence analysisAdd BLAST27

    Keywords - Cellular componenti

    Membrane

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003654861 – 534Inorganic phosphate transporter 1-6Add BLAST534

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q8H6H0

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q8H6H0

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

    Highly expressed in leaves and at low levels in roots. Expressed in leaf xylem parenchyma cells.1 Publication

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    In roots and leaves by phosphate starvation. Down-regulated in roots when colonized by the mycorrhizal fungus G. intraradices. Down-regulated by high phosphate in suspension cell culture.3 Publications

    Gene expression databases

    Genevisible search portal to normalized and curated expression data from Genevestigator

    More...
    Genevisiblei
    Q8H6H0, OS

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    4530.OS08T0564000-01

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni514 – 534DisorderedSequence analysisAdd BLAST21

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0252, Eukaryota

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_001265_46_14_1

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q8H6H0

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    LNSHWHL

    Database of Orthologous Groups

    More...
    OrthoDBi
    762280at2759

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR020846, MFS_dom
    IPR005828, MFS_sugar_transport-like
    IPR036259, MFS_trans_sf
    IPR004738, Phos_permease

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00083, Sugar_tr, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF103473, SSF103473, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR00887, 2A0109, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS50850, MFS, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    Q8H6H0-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MGGGGGEQQQ LEVLHALDVA KTQWYHFTAI VVAGMGFFTD AYDLFCISLV
    60 70 80 90 100
    TKLLGRIYYR VDGSPSPGTL PPHVSASVNG VAFVGTLSGQ LFFGWLGDKL
    110 120 130 140 150
    GRKRVYGITL MLMVLCSLAS ALSFGHTPTS VMATLCFFRF WLGFGIGGDY
    160 170 180 190 200
    PLSATIMSEY ANKKTRGAFI AAVFAMQGFG IITGGLVAIL VSASFRAAFP
    210 220 230 240 250
    APPYGEDPVA STPPQADFVW RIILMLGALP AALTYYWRTK MPETARYTAL
    260 270 280 290 300
    VANNAKQAAA DMSKVLQVVE MRNIGNNGGS RRPFGLFSGE FVRRHGLHLV
    310 320 330 340 350
    GTSATWLLLD IAFYSQNLFQ KDIFSAVGWI PKAATMSALE ELFRIARAQT
    360 370 380 390 400
    LIALCGTVPG YWFTVALIDV VGRFKIQAVG FFMMTLFMLT LALPYHHWTA
    410 420 430 440 450
    PGKNHVGFLL LYGLTFFFAN FGPNSTTFIV PAEIFPARLR ATCHGISAAS
    460 470 480 490 500
    GKLGAIVGSF GFLYLAQSPD RSKTEHGYPP GIGVRNSLFL LAACNLLGLL
    510 520 530
    FTFLVPESKG KSLEEMSGDA EAQEEAPPPL QTVL
    Length:534
    Mass (Da):57,786
    Last modified:March 1, 2003 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i46C9028EEBACEB40
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AF536966 Genomic DNA Translation: AAN39047.1
    AP004587 Genomic DNA Translation: BAD09632.1
    AP004623 Genomic DNA Translation: BAC55993.1
    AP008214 Genomic DNA Translation: BAF24441.1
    AP014964 Genomic DNA Translation: BAT06733.1
    AK119787 mRNA Translation: BAG99790.1

    NCBI Reference Sequences

    More...
    RefSeqi
    XP_015649112.1, XM_015793626.1

    Genome annotation databases

    Ensembl plant genome annotation project

    More...
    EnsemblPlantsi
    Os08t0564000-01; Os08t0564000-01; Os08g0564000

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    4346342

    Gramene; a comparative resource for plants

    More...
    Gramenei
    Os08t0564000-01; Os08t0564000-01; Os08g0564000

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    osa:4346342

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AF536966 Genomic DNA Translation: AAN39047.1
    AP004587 Genomic DNA Translation: BAD09632.1
    AP004623 Genomic DNA Translation: BAC55993.1
    AP008214 Genomic DNA Translation: BAF24441.1
    AP014964 Genomic DNA Translation: BAT06733.1
    AK119787 mRNA Translation: BAG99790.1
    RefSeqiXP_015649112.1, XM_015793626.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    STRINGi4530.OS08T0564000-01

    Protein family/group databases

    TCDBi2.A.1.9.5, the major facilitator superfamily (mfs)

    Proteomic databases

    PaxDbiQ8H6H0
    PRIDEiQ8H6H0

    Genome annotation databases

    EnsemblPlantsiOs08t0564000-01; Os08t0564000-01; Os08g0564000
    GeneIDi4346342
    GrameneiOs08t0564000-01; Os08t0564000-01; Os08g0564000
    KEGGiosa:4346342

    Phylogenomic databases

    eggNOGiKOG0252, Eukaryota
    HOGENOMiCLU_001265_46_14_1
    InParanoidiQ8H6H0
    OMAiLNSHWHL
    OrthoDBi762280at2759

    Gene expression databases

    GenevisibleiQ8H6H0, OS

    Family and domain databases

    InterProiView protein in InterPro
    IPR020846, MFS_dom
    IPR005828, MFS_sugar_transport-like
    IPR036259, MFS_trans_sf
    IPR004738, Phos_permease
    PfamiView protein in Pfam
    PF00083, Sugar_tr, 1 hit
    SUPFAMiSSF103473, SSF103473, 1 hit
    TIGRFAMsiTIGR00887, 2A0109, 1 hit
    PROSITEiView protein in PROSITE
    PS50850, MFS, 1 hit

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPHT16_ORYSJ
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8H6H0
    Secondary accession number(s): A0A0P0XIB8
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
    Last sequence update: March 1, 2003
    Last modified: June 2, 2021
    This is version 119 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families
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