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Entry version 110 (11 Dec 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Trihelix transcription factor GTL2

Gene

At5g28300

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor that binds specific DNA sequence.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Trihelix transcription factor GTL2
Alternative name(s):
GT2-LIKE protein 2
Short name:
AtGTL2
Trihelix DNA-binding protein GTL2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At5g28300
ORF Names:T8M17.70
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT5G28300

The Arabidopsis Information Resource

More...
TAIRi
locus:2185319 AT5G28300

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004057991 – 619Trihelix transcription factor GTL2Add BLAST619

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8H181

PRoteomics IDEntifications database

More...
PRIDEi
Q8H181

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8H181

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8H181 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8H181 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
18187, 4 interactors

Protein interaction database and analysis system

More...
IntActi
Q8H181, 3 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT5G28300.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8H181

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini102 – 154Myb-like 1PROSITE-ProRule annotationAdd BLAST53
Domaini459 – 526Myb-like 2PROSITE-ProRule annotationAdd BLAST68

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili307 – 361Sequence analysisAdd BLAST55

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi503 – 510Nuclear localization signalBy similarity8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi17 – 37Pro-richAdd BLAST21
Compositional biasi47 – 101His-richAdd BLAST55
Compositional biasi159 – 183Asn-richAdd BLAST25

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4282 Eukaryota
ENOG410YYXY LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000090988

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8H181

Identification of Orthologs from Complete Genome Data

More...
OMAi
RKIIHHH

Database of Orthologous Groups

More...
OrthoDBi
653125at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8H181

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017877 Myb-like_dom

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50090 MYB_LIKE, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8H181-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFDGGVPEQI HRFIASPPPP PPLPPHQPAA ERSLPFPVSF SSFNTNHQPQ
60 70 80 90 100
HMLSLDSRKI IHHHHHHHHH DIKDGGATTG EWIGQTDHDD SDNHHQHHHH
110 120 130 140 150
HPWCSDEVLA LLRFRSTVEN WFPEFTWEHT SRKLAEVGFK RSPQECKEKF
160 170 180 190 200
EEEERRYFNS NNNNNNNTND HQHIGNYNNK GNNYRIFSEV EEFYHHGHDN
210 220 230 240 250
EHVSSEVGDN QNKRTNLVEG KGNVGETVQD LMAEDKLRDQ DQGQVEEASM
260 270 280 290 300
ENQRNSIEVG KVGNVEDDAK SSSSSSLMMI MKEKKRKKRK KEKERFGVLK
310 320 330 340 350
GFCEGLVRNM IAQQEEMHKK LLEDMVKKEE EKIAREEAWK KQEIERVNKE
360 370 380 390 400
VEIRAQEQAM ASDRNTNIIK FISKFTDHDL DVVQNPTSPS QDSSSLALRK
410 420 430 440 450
TQGRRKFQTS SSLLPQTLTP HNLLTIDKSL EPFSTKTLKP KNQNPKPPKS
460 470 480 490 500
DDKSDLGKRW PKDEVLALIN IRRSISNMND DDHKDENSLS TSSKAVPLWE
510 520 530 540 550
RISKKMLEIG YKRSAKRCKE KWENINKYFR KTKDVNKKRP LDSRTCPYFH
560 570 580 590 600
QLTALYSQPP TGTTATTATT ATSARDLDTR PEENRVGSQD PDISVPMHVD
610
GDGAGDKSNV QFSGFDLEF
Length:619
Mass (Da):71,280
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE0471250DE3007FC
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK62408 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti280I → V in BAE99307 (Ref. 4) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF296835 Genomic DNA No translation available.
CP002688 Genomic DNA Translation: AED93787.1
AF386963 mRNA Translation: AAK62408.1 Different initiation.
AY081484 mRNA Translation: AAM10046.1
BT000461 mRNA Translation: AAN17438.1
BT008389 mRNA Translation: AAP37748.1
AK227285 mRNA Translation: BAE99307.1

NCBI Reference Sequences

More...
RefSeqi
NP_568506.2, NM_122713.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT5G28300.1; AT5G28300.1; AT5G28300

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
832914

Gramene; a comparative resource for plants

More...
Gramenei
AT5G28300.1; AT5G28300.1; AT5G28300

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT5G28300

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF296835 Genomic DNA No translation available.
CP002688 Genomic DNA Translation: AED93787.1
AF386963 mRNA Translation: AAK62408.1 Different initiation.
AY081484 mRNA Translation: AAM10046.1
BT000461 mRNA Translation: AAN17438.1
BT008389 mRNA Translation: AAP37748.1
AK227285 mRNA Translation: BAE99307.1
RefSeqiNP_568506.2, NM_122713.3

3D structure databases

SMRiQ8H181
ModBaseiSearch...

Protein-protein interaction databases

BioGridi18187, 4 interactors
IntActiQ8H181, 3 interactors
STRINGi3702.AT5G28300.1

PTM databases

iPTMnetiQ8H181

Proteomic databases

PaxDbiQ8H181
PRIDEiQ8H181

Genome annotation databases

EnsemblPlantsiAT5G28300.1; AT5G28300.1; AT5G28300
GeneIDi832914
GrameneiAT5G28300.1; AT5G28300.1; AT5G28300
KEGGiath:AT5G28300

Organism-specific databases

AraportiAT5G28300
TAIRilocus:2185319 AT5G28300

Phylogenomic databases

eggNOGiKOG4282 Eukaryota
ENOG410YYXY LUCA
HOGENOMiHOG000090988
InParanoidiQ8H181
OMAiRKIIHHH
OrthoDBi653125at2759
PhylomeDBiQ8H181

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8H181

Gene expression databases

ExpressionAtlasiQ8H181 baseline and differential
GenevisibleiQ8H181 AT

Family and domain databases

InterProiView protein in InterPro
IPR017877 Myb-like_dom
PROSITEiView protein in PROSITE
PS50090 MYB_LIKE, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGTL2_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8H181
Secondary accession number(s): Q0WU91, Q94F19
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 8, 2011
Last sequence update: March 1, 2003
Last modified: December 11, 2019
This is version 110 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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