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Entry version 93 (11 Dec 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Scarecrow-like protein 5

Gene

SCL5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable transcription factor involved in plant development.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scarecrow-like protein 5
Short name:
AtSCL5
Alternative name(s):
GRAS family protein 6
Short name:
AtGRAS-6
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCL5
Ordered Locus Names:At1g50600
ORF Names:F11F12.8, F17J6.12
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G50600

The Arabidopsis Information Resource

More...
TAIRi
locus:2008076 AT1G50600

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003508491 – 597Scarecrow-like protein 5Add BLAST597

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8H125

PRoteomics IDEntifications database

More...
PRIDEi
Q8H125

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8H125

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in seedlings, roots, shoots, leaves, flowers and siliques.2 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8H125 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8H125 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
26707, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8H125, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT1G50600.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8H125

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini218 – 597GRASPROSITE-ProRule annotationAdd BLAST380

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni225 – 285Leucine repeat I (LRI)PROSITE-ProRule annotationAdd BLAST61
Regioni304 – 369VHIIDPROSITE-ProRule annotationAdd BLAST66
Regioni385 – 417Leucine repeat II (LRII)PROSITE-ProRule annotationAdd BLAST33
Regioni426 – 520PFYREPROSITE-ProRule annotationAdd BLAST95
Regioni523 – 597SAWPROSITE-ProRule annotationAdd BLAST75

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi335 – 339VHIIDPROSITE-ProRule annotation5

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi123 – 162Asn-richAdd BLAST40

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GRAS family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IPGZ Eukaryota
ENOG4111JS8 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000238577

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8H125

Database of Orthologous Groups

More...
OrthoDBi
483185at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8H125

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005202 TF_GRAS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03514 GRAS, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50985 GRAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8H125-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLSVFIIPL VESRQASGII NKQSTSLLIR FSLYLEASIS TKSFFSKSQR
60 70 80 90 100
ISQTQSPICL SANYYQPDNL DMEATQKHMI QEGSSMFYHQ PSSVKQMDLS
110 120 130 140 150
VQTFDSYCTL ESSSGTKSHP CLNNKNNSSS TTSFSSNESP ISQANNNNLS
160 170 180 190 200
RFNNHSPEEN NNSPLSGSSA TNTNETELSL MLKDLETAMM EPDVDNSYNN
210 220 230 240 250
QGGFGQQHGV VSSAMYRSME MISRGDLKGV LYECAKAVEN YDLEMTDWLI
260 270 280 290 300
SQLQQMVSVS GEPVQRLGAY MLEGLVARLA SSGSSIYKAL RCKDPTGPEL
310 320 330 340 350
LTYMHILYEA CPYFKFGYES ANGAIAEAVK NESFVHIIDF QISQGGQWVS
360 370 380 390 400
LIRALGARPG GPPNVRITGI DDPRSSFARQ GGLELVGQRL GKLAEMCGVP
410 420 430 440 450
FEFHGAALCC TEVEIEKLGV RNGEALAVNF PLVLHHMPDE SVTVENHRDR
460 470 480 490 500
LLRLVKHLSP NVVTLVEQEA NTNTAPFLPR FVETMNHYLA VFESIDVKLA
510 520 530 540 550
RDHKERINVE QHCLAREVVN LIACEGVERE ERHEPLGKWR SRFHMAGFKP
560 570 580 590
YPLSSYVNAT IKGLLESYSE KYTLEERDGA LYLGWKNQPL ITSCAWR
Length:597
Mass (Da):66,641
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF04283230556502
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8AW83A0A1P8AW83_ARATH
Scarecrow-like 5
SCL5 scarecrow-like 5, At1g50600, F11F12.8, F11F12_8
526Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8AW90A0A1P8AW90_ARATH
Scarecrow-like 5
SCL5 scarecrow-like 5, At1g50600, F11F12.8, F11F12_8
601Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF87875 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG51190 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAK62666 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti292 – 294CKD → GTS in AAD24405 (PubMed:10341448).Curated3
Sequence conflicti562K → E in AAK62666 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC012561 Genomic DNA Translation: AAF87875.1 Sequence problems.
AC079279 Genomic DNA Translation: AAG51190.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE32568.1
AY034929 mRNA Translation: AAK59436.2
AY039611 mRNA Translation: AAK62666.1 Different initiation.
BT000883 mRNA Translation: AAN41283.1
AF036302 mRNA Translation: AAD24405.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E96542
T51236

NCBI Reference Sequences

More...
RefSeqi
NP_001323176.1, NM_001333446.1
NP_175475.2, NM_103942.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G50600.1; AT1G50600.1; AT1G50600

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
841482

Gramene; a comparative resource for plants

More...
Gramenei
AT1G50600.1; AT1G50600.1; AT1G50600

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G50600

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012561 Genomic DNA Translation: AAF87875.1 Sequence problems.
AC079279 Genomic DNA Translation: AAG51190.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE32568.1
AY034929 mRNA Translation: AAK59436.2
AY039611 mRNA Translation: AAK62666.1 Different initiation.
BT000883 mRNA Translation: AAN41283.1
AF036302 mRNA Translation: AAD24405.1
PIRiE96542
T51236
RefSeqiNP_001323176.1, NM_001333446.1
NP_175475.2, NM_103942.3

3D structure databases

SMRiQ8H125
ModBaseiSearch...

Protein-protein interaction databases

BioGridi26707, 2 interactors
IntActiQ8H125, 1 interactor
STRINGi3702.AT1G50600.1

PTM databases

iPTMnetiQ8H125

Proteomic databases

PaxDbiQ8H125
PRIDEiQ8H125

Genome annotation databases

EnsemblPlantsiAT1G50600.1; AT1G50600.1; AT1G50600
GeneIDi841482
GrameneiAT1G50600.1; AT1G50600.1; AT1G50600
KEGGiath:AT1G50600

Organism-specific databases

AraportiAT1G50600
TAIRilocus:2008076 AT1G50600

Phylogenomic databases

eggNOGiENOG410IPGZ Eukaryota
ENOG4111JS8 LUCA
HOGENOMiHOG000238577
InParanoidiQ8H125
OrthoDBi483185at2759
PhylomeDBiQ8H125

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8H125

Gene expression databases

ExpressionAtlasiQ8H125 baseline and differential
GenevisibleiQ8H125 AT

Family and domain databases

InterProiView protein in InterPro
IPR005202 TF_GRAS
PfamiView protein in Pfam
PF03514 GRAS, 1 hit
PROSITEiView protein in PROSITE
PS50985 GRAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCL5_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8H125
Secondary accession number(s): Q7EXH0
, Q94BW9, Q9LPT0, Q9XE53
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 23, 2008
Last sequence update: March 1, 2003
Last modified: December 11, 2019
This is version 93 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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