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Protein

Type IV inositol polyphosphate 5-phosphatase 3

Gene

IP5P3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Has phosphatase activity toward PtdIns(4,5)P2 and PtdIns(3,4,5)P3.1 Publication

Catalytic activityi

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.1 Publication
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciARA:AT1G71710-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Type IV inositol polyphosphate 5-phosphatase 3Curated (EC:3.1.3.361 Publication, EC:3.1.3.861 Publication)
Short name:
At5PTase3Curated
Gene namesi
Name:IP5P3Curated
Ordered Locus Names:At1g71710Imported
ORF Names:F14O23_9Imported, F26A9.1Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G71710
TAIRilocus:2013031 AT1G71710

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004332541 – 664Type IV inositol polyphosphate 5-phosphatase 3Add BLAST664

Proteomic databases

PaxDbiQ8H0Z6

PTM databases

iPTMnetiQ8H0Z6

Expressioni

Gene expression databases

ExpressionAtlasiQ8H0Z6 baseline and differential
GenevisibleiQ8H0Z6 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G71710.1

Structurei

3D structure databases

ProteinModelPortaliQ8H0Z6
SMRiQ8H0Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni514 – 529Catalytic 1By similarityAdd BLAST16
Regioni592 – 607Catalytic 2By similarityAdd BLAST16

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi94 – 99Poly-AlaSequence analysis6
Compositional biasi249 – 254Poly-GluSequence analysis6

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000241161
InParanoidiQ8H0Z6
OMAiFCFINTH
OrthoDBiEOG093605AX
PhylomeDBiQ8H0Z6

Family and domain databases

Gene3Di3.60.10.10, 2 hits
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8H0Z6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSPVEPAGIM KKSHRQKSQR LWAKLVMRKW LNISGRDPEY GADTDNESEN
60 70 80 90 100
EDAREDNDDS SSDEEGGSGS RGRESKVYEN AEDAIAAASA VVDAAAAAAE
110 120 130 140 150
FISNDAPMKL RRRNSETLRA QYINNKEIRV CVGTWNVGGI SPPSDLDIDD
160 170 180 190 200
WIEINQPADI YVLGLQEIVP LNAGNILGAE DDRPVAKWEE VIREALNRVR
210 220 230 240 250
PKLSGVKSYS DPPSPGRFKP FEETHDIIEE EVAFESDSDA GVEIHPIDEE
260 270 280 290 300
EEEETDRLWA LKHDGGVIGE VKTLVDPNTG LPVVEIKRQF SIPKKLDRQL
310 320 330 340 350
CLRADSFKGI SDDDSTQTGM KTINRMLSGK ERIGLSWPEP PLNMLGPCVL
360 370 380 390 400
DRQPSIKTVK SLKTAKSFKA YSSFKSVAGN NNGIPPEVLA LAEMDLKLLM
410 420 430 440 450
ERKRRPAYVR LVSKQMVGIL LTIWVKRSLR KHIQNVRVST VGVGVMGYIG
460 470 480 490 500
NKGAVSVSMS INQTFFCFIN THLTAGEREV DQIKRNADVH EIHKRTVFHS
510 520 530 540 550
VSALGLPKLI YDHERIIWLG DLNYRLSSSY EKTRDLISKR EWSKLLEYDQ
560 570 580 590 600
LVKEYRKGRA FDGWSEGTLH FPPTYKYQAN SDEYTANDGK APKRTPAWCD
610 620 630 640 650
RVLSYGKGMR LVHYRRTEQK FSDHRPVTAI YMAEVEVFSA RKLQRALTFT
660
DAEIEDEGLV AVLV
Length:664
Mass (Da):74,780
Last modified:March 1, 2003 - v1
Checksum:i46B578594A21A8D4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4IA20F4IA20_ARATH
DNAse I-like superfamily protein
At1g71710, F14O23.9, F14O23_9
655Annotation score:

Sequence cautioni

The sequence AAF43224 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti165L → S in AAK82558 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012654 Genomic DNA Translation: AAF43224.1 Sequence problems.
AC016163 Genomic DNA Translation: AAG51823.1
CP002684 Genomic DNA Translation: AEE35221.1
AY048296 mRNA Translation: AAK82558.1
BT001070 mRNA Translation: AAN46835.1
PIRiD96739
RefSeqiNP_565023.1, NM_105829.4 [Q8H0Z6-1]
UniGeneiAt.12019

Genome annotation databases

EnsemblPlantsiAT1G71710.1; AT1G71710.1; AT1G71710 [Q8H0Z6-1]
GeneIDi843501
GrameneiAT1G71710.1; AT1G71710.1; AT1G71710 [Q8H0Z6-1]
KEGGiath:AT1G71710

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012654 Genomic DNA Translation: AAF43224.1 Sequence problems.
AC016163 Genomic DNA Translation: AAG51823.1
CP002684 Genomic DNA Translation: AEE35221.1
AY048296 mRNA Translation: AAK82558.1
BT001070 mRNA Translation: AAN46835.1
PIRiD96739
RefSeqiNP_565023.1, NM_105829.4 [Q8H0Z6-1]
UniGeneiAt.12019

3D structure databases

ProteinModelPortaliQ8H0Z6
SMRiQ8H0Z6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G71710.1

PTM databases

iPTMnetiQ8H0Z6

Proteomic databases

PaxDbiQ8H0Z6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G71710.1; AT1G71710.1; AT1G71710 [Q8H0Z6-1]
GeneIDi843501
GrameneiAT1G71710.1; AT1G71710.1; AT1G71710 [Q8H0Z6-1]
KEGGiath:AT1G71710

Organism-specific databases

AraportiAT1G71710
TAIRilocus:2013031 AT1G71710

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
COG5411 LUCA
HOGENOMiHOG000241161
InParanoidiQ8H0Z6
OMAiFCFINTH
OrthoDBiEOG093605AX
PhylomeDBiQ8H0Z6

Enzyme and pathway databases

BioCyciARA:AT1G71710-MONOMER

Miscellaneous databases

PROiPR:Q8H0Z6

Gene expression databases

ExpressionAtlasiQ8H0Z6 baseline and differential
GenevisibleiQ8H0Z6 AT

Family and domain databases

Gene3Di3.60.10.10, 2 hits
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR000300 IPPc
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SUPFAMiSSF56219 SSF56219, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiIP5P3_ARATH
AccessioniPrimary (citable) accession number: Q8H0Z6
Secondary accession number(s): Q94AB6, Q9C9J4, Q9M9H5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 24, 2015
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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