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Entry version 120 (12 Aug 2020)
Sequence version 2 (16 May 2006)
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Protein

ABC transporter G family member 30

Gene

ABCG30

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Together with ABCG40, import into the embryo the abscisic acid (ABA) delivered from the endosperm via ABCG25 and ABCG31-mediated export to suppress radicle extension and subsequent embryonic growth (PubMed:26334616). Involved in root secretion of phytochemicals (phenolics and sugars) which regulate soil microbiota, influencing both fungal and bacterial communities (PubMed:19854857). May be a general defense protein (By similarity).By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi174 – 181ATP 1PROSITE-ProRule annotation8
Nucleotide bindingi845 – 852ATP 2PROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAbscisic acid signaling pathway, Transport
LigandATP-binding, Nucleotide-binding

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.1.205.28, the atp-binding cassette (abc) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ABC transporter G family member 301 Publication
Short name:
ABC transporter ABCG.301 Publication
Short name:
AtABCG301 Publication
Alternative name(s):
Pleiotropic drug resistance protein 22 Publications
Short name:
AtPDR22 Publications
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ABCG301 Publication
Synonyms:PDR22 Publications
Ordered Locus Names:At4g15230/At4g15220Imported
ORF Names:dl3660w/dl3655wImported, FCAALL.241Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G15230

The Arabidopsis Information Resource

More...
TAIRi
locus:2129830, AT4G15230

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei510 – 530HelicalSequence analysisAdd BLAST21
Transmembranei553 – 573HelicalSequence analysisAdd BLAST21
Transmembranei582 – 602HelicalSequence analysisAdd BLAST21
Transmembranei628 – 648HelicalSequence analysisAdd BLAST21
Transmembranei652 – 672HelicalSequence analysisAdd BLAST21
Transmembranei679 – 699HelicalSequence analysisAdd BLAST21
Transmembranei738 – 758HelicalSequence analysisAdd BLAST21
Transmembranei1144 – 1164HelicalSequence analysisAdd BLAST21
Transmembranei1179 – 1199HelicalSequence analysisAdd BLAST21
Transmembranei1228 – 1248HelicalSequence analysisAdd BLAST21
Transmembranei1263 – 1283HelicalSequence analysisAdd BLAST21
Transmembranei1289 – 1309HelicalSequence analysisAdd BLAST21
Transmembranei1317 – 1337HelicalSequence analysisAdd BLAST21
Transmembranei1372 – 1392HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Early seeds germination on imbibition without stratification, and reduced abscisic acid (ABA)-mediated inhibition of stratified seeds germination (PubMed:26334616). Altered root exudation of phytochemicals, with increased phenolics (e.g. benzoic acid, salicylic acid, syringic acid, tartaric acid, lactic acid, alpha-linolenic acid, cyanidin, sinapoyl malate, valine and indole 3-acetic acid) and decreased sugars levels (e.g. raffinose, glucose, fructose and mannitol), leading to an overhaul of natural soil microbiota, including both fungal and bacterial communities; this phenotype is associated with an up-regulation of some genes involved in biosynthesis and transport of secondary metabolites, but the down-regulation of some sugar transporters (PubMed:19854857).2 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002346291 – 1400ABC transporter G family member 30Add BLAST1400

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi116N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi472N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi899N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi1040N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8GZ52

PRoteomics IDEntifications database

More...
PRIDEi
Q8GZ52

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
245153 [Q8GZ52-1]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Confined to roots (PubMed:12430018). In seeds, mainly expressed in the embryo and, to a lesser extent, in the endosperm (PubMed:26334616).2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Repressed by cold/dark treatment.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8GZ52, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8GZ52, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
12484, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT4G15230.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8GZ52

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini141 – 414ABC transporter 1PROSITE-ProRule annotationAdd BLAST274
Domaini492 – 704ABC transmembrane type-2 1Sequence analysisAdd BLAST213
Domaini808 – 1053ABC transporter 2PROSITE-ProRule annotationAdd BLAST246
Domaini1125 – 1339ABC transmembrane type-2 2Sequence analysisAdd BLAST215

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0065, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000604_35_6_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8GZ52

Database of Orthologous Groups

More...
OrthoDBi
37708at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03232, ABCG_PDR_domain2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR029481, ABC_trans_N
IPR003439, ABC_transporter-like
IPR034003, ABCG_PDR_2
IPR027417, P-loop_NTPase
IPR013581, PDR_assoc

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01061, ABC2_membrane, 2 hits
PF00005, ABC_tran, 2 hits
PF14510, ABC_trans_N, 1 hit
PF08370, PDR_assoc, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50893, ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8GZ52-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIQTGEEDEE KATSLEVEFA SGNGVDDEEE LRLQWATVER LPTFKRVTTA
60 70 80 90 100
LLARDEVSGK GRVIDVTRLE GAERRLLIEM LVKQIEDDNL RLLRKIRKRI
110 120 130 140 150
DKVGIELPTV EVRFNNLSVE AECQVIHGKP IPTLWNTIKG LLSEFICSKK
160 170 180 190 200
ETKIGILKGV SGIVRPGRMT LLLGPPGCGK TTLLQALSGK FSDSVKVGGE
210 220 230 240 250
VCYNGCSLSE FIPEKTSSYI SQNDLHIPEL SVRETLDFSA CCQGIGSRME
260 270 280 290 300
IMKEISRMEK LQEIIPDPAV DAYMKATSVE GLKNNLQTDY ILKILGLDIC
310 320 330 340 350
ADTRVGDATR PGISGGEKRR LTTGELVVGP ATTLFMDEIS NGLDSSTTFQ
360 370 380 390 400
IVSCLQQLAH IAEATILISL LQPAPETFEL FDDVILMGEG KIIYHAPRAD
410 420 430 440 450
ICRFFEEFGF KCPERKGVAD FLQEIMSKKD QEQYWCHRDK PYSYISVDSF
460 470 480 490 500
INKFKESNLG LLLKEELSKP FNKSQTRKDG LCYKKYSLGK WEMLKACSRR
510 520 530 540 550
EFLLMKRNSF IYLFKSALLV FNALVTMTVF LQVGATTDSL HGNYLMGSLF
560 570 580 590 600
TALFRLLADG LPELTLTISR LGVFCKQKDL YFYPAWAYAI PSIILKIPLS
610 620 630 640 650
VLDSFIWTLL TYYVIGYSPE VKRFFLQFLI LSTFNLSCVS MFRAIAAIFR
660 670 680 690 700
TIIASTITGA ISILVLSLFG GFVIPKSSMP AWLGWGFWLS PLSYAEIGLT
710 720 730 740 750
ANEFFSPRWS KVISSKTTAG EQMLDIRGLN FGRHSYWTAF GALVGFVLFF
760 770 780 790 800
NALYVLALTY QNNPQRSRAI ISHEKYSRPI EEDFKPCPKI TSRAKTGKII
810 820 830 840 850
LPFKPLTVTF QNVQYYIETP QGKTRQLLSD ITGALKPGVL TSLMGVSGAG
860 870 880 890 900
KTTLLDVLSG RKTRGIIKGE IKVGGYPKVQ ETFARVSGYC EQFDIHSPNI
910 920 930 940 950
TVEESLKYSA WLRLPYNIDS KTKNELVKEV LETVELDDIK DSVVGLPGIS
960 970 980 990 1000
GLSIEQRKRL TIAVELVANP SIIFMDEPTT GLDARAAAIV MRAVKNVAET
1010 1020 1030 1040 1050
GRTVVCTIHQ PSIDIFETFD ELILMKNGGQ LVYYGPPGQN SSKVIEYFES
1060 1070 1080 1090 1100
FSGLPKIQKN CNPATWILDI TSKSAEEKLG IDFSQSYKDS TLYKQNKMVV
1110 1120 1130 1140 1150
EQLSSASLGS EALRFPSQFS QTAWVQLKAC LWKQHYSYWR NPSHNITRIV
1160 1170 1180 1190 1200
FILLDSTLCG LLFWQKAEDI NNQQDLISIF GSMYTLVVFP GMNNCAAVIN
1210 1220 1230 1240 1250
FIAAERNVFY RERFARMYSS WAYSFSQVLI EVPYSLLQSL LCTIIVYPTI
1260 1270 1280 1290 1300
GYHMSVYKMF WSLYSIFCSL LIFNYSGMLM VALTPNIHMA VTLRSSFFSM
1310 1320 1330 1340 1350
LNLFAGFVIP KQKIPKWWIW MYYLSPTSWV LEGLLSSQYG DVDKEILVFG
1360 1370 1380 1390 1400
EKKRVSAFLE DYFGYKHESL AVVAFVLIAY PIIVATLFAF FMSKLSFQKK
Length:1,400
Mass (Da):157,768
Last modified:May 16, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEED12151C91EB57B
GO
Isoform 2 (identifier: Q8GZ52-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-640: Missing.

Show »
Length:760
Mass (Da):85,753
Checksum:i3A2E671A7A7B0D89
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8B5S3A0A1P8B5S3_ARATH
Pleiotropic drug resistance 2
ABCG30 ATP-binding cassette G30, ATPDR2, PDR2, pleiotropic drug resistance 2, At4g15230
1,321Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8B5R0A0A1P8B5R0_ARATH
Pleiotropic drug resistance 2
ABCG30 ATP-binding cassette G30, ATPDR2, PDR2, pleiotropic drug resistance 2, At4g15230
1,324Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB10301 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g15220 and At4g15230.Curated
The sequence CAB45997 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g15220 and At4g15230.Curated
The sequence CAB78564 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g15220 and At4g15230.Curated
The sequence CAB78565 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g15220 and At4g15230.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0183921 – 640Missing in isoform 2. 1 PublicationAdd BLAST640

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z97338 Genomic DNA Translation: CAB10301.1 Sequence problems.
Z97338 Genomic DNA Translation: CAB45997.1 Sequence problems.
AL161540 Genomic DNA Translation: CAB78564.1 Sequence problems.
AL161540 Genomic DNA Translation: CAB78565.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83571.1
CP002687 Genomic DNA Translation: ANM66937.1
AK117203 mRNA Translation: BAC41879.1
BK001000 Genomic DNA Translation: DAA00869.1

Protein sequence database of the Protein Information Resource

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PIRi
C71416
D71416
G85167

NCBI Reference Sequences

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RefSeqi
NP_001319944.1, NM_001341010.1 [Q8GZ52-1]
NP_193258.3, NM_117611.5 [Q8GZ52-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G15230.1; AT4G15230.1; AT4G15230 [Q8GZ52-1]
AT4G15230.3; AT4G15230.3; AT4G15230 [Q8GZ52-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
827187

Gramene; a comparative resource for plants

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Gramenei
AT4G15230.1; AT4G15230.1; AT4G15230 [Q8GZ52-1]
AT4G15230.3; AT4G15230.3; AT4G15230 [Q8GZ52-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT4G15230

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z97338 Genomic DNA Translation: CAB10301.1 Sequence problems.
Z97338 Genomic DNA Translation: CAB45997.1 Sequence problems.
AL161540 Genomic DNA Translation: CAB78564.1 Sequence problems.
AL161540 Genomic DNA Translation: CAB78565.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83571.1
CP002687 Genomic DNA Translation: ANM66937.1
AK117203 mRNA Translation: BAC41879.1
BK001000 Genomic DNA Translation: DAA00869.1
PIRiC71416
D71416
G85167
RefSeqiNP_001319944.1, NM_001341010.1 [Q8GZ52-1]
NP_193258.3, NM_117611.5 [Q8GZ52-1]

3D structure databases

SMRiQ8GZ52
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi12484, 1 interactor
STRINGi3702.AT4G15230.1

Protein family/group databases

TCDBi3.A.1.205.28, the atp-binding cassette (abc) superfamily

Proteomic databases

PaxDbiQ8GZ52
PRIDEiQ8GZ52
ProteomicsDBi245153 [Q8GZ52-1]

Genome annotation databases

EnsemblPlantsiAT4G15230.1; AT4G15230.1; AT4G15230 [Q8GZ52-1]
AT4G15230.3; AT4G15230.3; AT4G15230 [Q8GZ52-1]
GeneIDi827187
GrameneiAT4G15230.1; AT4G15230.1; AT4G15230 [Q8GZ52-1]
AT4G15230.3; AT4G15230.3; AT4G15230 [Q8GZ52-1]
KEGGiath:AT4G15230

Organism-specific databases

AraportiAT4G15230
TAIRilocus:2129830, AT4G15230

Phylogenomic databases

eggNOGiKOG0065, Eukaryota
HOGENOMiCLU_000604_35_6_1
InParanoidiQ8GZ52
OrthoDBi37708at2759

Miscellaneous databases

Protein Ontology

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PROi
PR:Q8GZ52

Gene expression databases

ExpressionAtlasiQ8GZ52, baseline and differential
GenevisibleiQ8GZ52, AT

Family and domain databases

CDDicd03232, ABCG_PDR_domain2, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR013525, ABC_2_trans
IPR029481, ABC_trans_N
IPR003439, ABC_transporter-like
IPR034003, ABCG_PDR_2
IPR027417, P-loop_NTPase
IPR013581, PDR_assoc
PfamiView protein in Pfam
PF01061, ABC2_membrane, 2 hits
PF00005, ABC_tran, 2 hits
PF14510, ABC_trans_N, 1 hit
PF08370, PDR_assoc, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50893, ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAB30G_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8GZ52
Secondary accession number(s): O23376, O23377, Q7PC89
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 16, 2006
Last modified: August 12, 2020
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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