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UniProtKB - Q8GXR2 (PLT6_ARATH)

Entry version 107 (23 Feb 2022)
Sequence version 2 (28 Nov 2006)
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Protein

Probable polyol transporter 6

Gene

PLT6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plasma membrane sugar-proton symporter.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processSugar transport, Symport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable polyol transporter 6
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLT6
Ordered Locus Names:At4g36670
ORF Names:AP22.86, C7A10.690
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT4G36670

The Arabidopsis Information Resource

More...TAIRi		locus:2115415, AT4G36670

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei25 – 45Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei54 – 74Helical; Name=2Sequence analysisAdd BLAST21
Transmembranei85 – 105Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei116 – 136Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei142 – 162Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei177 – 197Helical; Name=6Sequence analysisAdd BLAST21
Transmembranei275 – 295Helical; Name=7Sequence analysisAdd BLAST21
Transmembranei313 – 333Helical; Name=8Sequence analysisAdd BLAST21
Transmembranei343 – 363Helical; Name=9Sequence analysisAdd BLAST21
Transmembranei372 – 392Helical; Name=10Sequence analysisAdd BLAST21
Transmembranei414 – 434Helical; Name=11Sequence analysisAdd BLAST21
Transmembranei444 – 464Helical; Name=12Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002598741 – 493Probable polyol transporter 6Add BLAST493

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8GXR2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		234773

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8GXR2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8GXR2, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		3702.AT4G36670.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8GXR2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0254, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001265_30_5_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8GXR2

Identification of Orthologs from Complete Genome Data

More...OMAi		ILTKPSW

Database of Orthologous Groups

More...OrthoDBi		430696at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8GXR2

Family and domain databases

Conserved Domains Database

More...CDDi		cd17437, MFS_PLT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1250.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR044776, PLT1-6
IPR045262, STP/PLT_plant
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS

The PANTHER Classification System

More...PANTHERi		PTHR23500, PTHR23500, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00083, Sugar_tr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00171, SUGRTRNSPORT

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103473, SSF103473, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00879, SP, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8GXR2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADQISGEKP AGVNRFALQC AIVASIVSII FGYDTGVMSG AMVFIEEDLK 
        60         70         80         90        100
TNDVQIEVLT GILNLCALVG SLLAGRTSDI IGRRYTIVLA SILFMLGSIL 
       110        120        130        140        150
MGWGPNYPVL LSGRCTAGLG VGFALMVAPV YSAEIATASH RGLLASLPHL 
       160        170        180        190        200
CISIGILLGY IVNYFFSKLP MHIGWRLMLG IAAVPSLVLA FGILKMPESP 
       210        220        230        240        250
RWLIMQGRLK EGKEILELVS NSPEEAELRF QDIKAAAGID PKCVDDVVKM 
       260        270        280        290        300
EGKKTHGEGV WKELILRPTP AVRRVLLTAL GIHFFQHASG IEAVLLYGPR 
       310        320        330        340        350
IFKKAGITTK DKLFLVTIGV GIMKTTFIFT ATLLLDKVGR RKLLLTSVGG 
       360        370        380        390        400
MVIALTMLGF GLTMAQNAGG KLAWALVLSI VAAYSFVAFF SIGLGPITWV 
       410        420        430        440        450
YSSEVFPLKL RAQGASLGVA VNRVMNATVS MSFLSLTSAI TTGGAFFMFA 
       460        470        480        490 
GVAAVAWNFF FFLLPETKGK SLEEIEALFQ RDGDKVRGEN GAA
Length:493
Mass (Da):52,923
Last modified:November 28, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE49D9E7298E9982A
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC42720 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Z99708 Genomic DNA Translation: CAB16808.1
AL161589 Genomic DNA Translation: CAB80333.1
CP002687 Genomic DNA Translation: AEE86685.1
AK118092 mRNA Translation: BAC42720.1 Different initiation.

Protein sequence database of the Protein Information Resource

More...PIRi		A85433

NCBI Reference Sequences

More...RefSeqi		NP_195385.1, NM_119831.3

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT4G36670.1; AT4G36670.1; AT4G36670

Database of genes from NCBI RefSeq genomes

More...GeneIDi		829820

Gramene; a comparative resource for plants

More...Gramenei		AT4G36670.1; AT4G36670.1; AT4G36670

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT4G36670

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z99708 Genomic DNA Translation: CAB16808.1
AL161589 Genomic DNA Translation: CAB80333.1
CP002687 Genomic DNA Translation: AEE86685.1
AK118092 mRNA Translation: BAC42720.1 Different initiation.
PIRiA85433
RefSeqiNP_195385.1, NM_119831.3

3D structure databases

SMRiQ8GXR2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT4G36670.1

Proteomic databases

PaxDbiQ8GXR2
ProteomicsDBi234773

Genome annotation databases

EnsemblPlantsiAT4G36670.1; AT4G36670.1; AT4G36670
GeneIDi829820
GrameneiAT4G36670.1; AT4G36670.1; AT4G36670
KEGGiath:AT4G36670

Organism-specific databases

AraportiAT4G36670
TAIRilocus:2115415, AT4G36670

Phylogenomic databases

eggNOGiKOG0254, Eukaryota
HOGENOMiCLU_001265_30_5_1
InParanoidiQ8GXR2
OMAiILTKPSW
OrthoDBi430696at2759
PhylomeDBiQ8GXR2

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q8GXR2

Gene expression databases

ExpressionAtlasiQ8GXR2, baseline and differential
GenevisibleiQ8GXR2, AT

Family and domain databases

CDDicd17437, MFS_PLT, 1 hit
Gene3Di1.20.1250.20, 1 hit
InterProiView protein in InterPro
IPR020846, MFS_dom
IPR005828, MFS_sugar_transport-like
IPR036259, MFS_trans_sf
IPR044776, PLT1-6
IPR045262, STP/PLT_plant
IPR003663, Sugar/inositol_transpt
IPR005829, Sugar_transporter_CS
PANTHERiPTHR23500, PTHR23500, 1 hit
PfamiView protein in Pfam
PF00083, Sugar_tr, 1 hit
PRINTSiPR00171, SUGRTRNSPORT
SUPFAMiSSF103473, SSF103473, 1 hit
TIGRFAMsiTIGR00879, SP, 1 hit
PROSITEiView protein in PROSITE
PS50850, MFS, 1 hit
PS00216, SUGAR_TRANSPORT_1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLT6_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8GXR2
Secondary accession number(s): O23213
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 28, 2006
Last modified: February 23, 2022
This is version 107 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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