UniProtKB - Q8GXM8 (DTX2_ARATH)
Protein
Protein DETOXIFICATION 2
Gene
DTX2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
GO - Molecular functioni
- antiporter activity Source: InterPro
- transmembrane transporter activity Source: GO_Central
- xenobiotic transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Protein DETOXIFICATION 21 PublicationShort name: AtDTX21 Publication Alternative name(s): Multidrug and toxic compound extrusion protein 2Curated Short name: MATE protein 2Curated |
Gene namesi | Name:DTX21 Publication Ordered Locus Names:At2g04080Imported ORF Names:F3L12.9Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G04080 |
TAIRi | locus:2050185, AT2G04080 |
Subcellular locationi
Other locations
- Membrane Sequence analysis; Multi-pass membrane protein Sequence analysis
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 34 – 56 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 73 – 93 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 117 – 137 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 146 – 166 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 184 – 204 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 208 – 228 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 260 – 280 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 289 – 309 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 331 – 351 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 370 – 390 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 402 – 422 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 433 – 453 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000405322 | 1 – 476 | Protein DETOXIFICATION 2Add BLAST | 476 |
Proteomic databases
PaxDbi | Q8GXM8 |
PRIDEi | Q8GXM8 |
ProteomicsDBi | 221872 |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8GXM8, baseline and differential |
Genevisiblei | Q8GXM8, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 345, 36 interactors |
IntActi | Q8GXM8, 35 interactors |
Family & Domainsi
Sequence similaritiesi
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1347, Eukaryota |
HOGENOMi | CLU_012893_1_4_1 |
InParanoidi | Q8GXM8 |
OMAi | ATNIPIC |
OrthoDBi | 743037at2759 |
PhylomeDBi | Q8GXM8 |
Family and domain databases
InterProi | View protein in InterPro IPR002528, MATE_fam |
Pfami | View protein in Pfam PF01554, MatE, 2 hits |
TIGRFAMsi | TIGR00797, matE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q8GXM8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEEPFLPRDE QLVSCKSTWQ SGQVTVELKK VSRLAAPMAT VTIAQYLLPV
60 70 80 90 100
ISVMVAGHIG ELELAGVALA TSFTNVSGFS IMFGLVGALE TLCGQAYGAE
110 120 130 140 150
QYEKIGTYTY SAMASNIPIC FIISILWIYI EKLLITLGQE PDISRVAGSY
160 170 180 190 200
SLWLVPALFA HAIFLPLTRF LLAQGLVISL LYSAMTTLLF HIAVCWTLVF
210 220 230 240 250
ALGLGSNGAA IAISLSFWFY AVILSCHVRF FSSCEKTRGF VSNDFMSSIK
260 270 280 290 300
QYFQYGVPSA GLICLEWWLF ELLILCSGLL PNPKLETSVL SICLTIGTLH
310 320 330 340 350
YVIPSGVAAA VSTRVSNKLG AGNPQVARVS VLAGLCLWLV ESAFFSTLLF
360 370 380 390 400
TCRNIIGYTF SNSKEVVDYV ADISPLLCLS FILDGLTAVL NGVARGCGWQ
410 420 430 440 450
HIGALINVVA YYLVGAPVGV YLAFSREWNG KGLWCGVMVG SAVQATLLAI
460 470
VTASMNWKEQ AEKARKRIIS TENGLV
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8B0Y4 | A0A1P8B0Y4_ARATH | Protein DETOXIFICATION | At2g04080, F3L12.9, F3L12_9 | 469 | Annotation score: |
Sequence cautioni
The sequence AAD28684 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007178 Genomic DNA Translation: AAD28684.1 Sequence problems. CP002685 Genomic DNA Translation: AEC05797.1 AK118147 mRNA Translation: BAC42772.1 BT005511 mRNA Translation: AAO63931.1 |
PIRi | D84454 |
RefSeqi | NP_001324727.1, NM_001335215.1 NP_178497.2, NM_126449.5 |
Genome annotation databases
EnsemblPlantsi | AT2G04080.1; AT2G04080.1; AT2G04080 |
GeneIDi | 814944 |
Gramenei | AT2G04080.1; AT2G04080.1; AT2G04080 |
KEGGi | ath:AT2G04080 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007178 Genomic DNA Translation: AAD28684.1 Sequence problems. CP002685 Genomic DNA Translation: AEC05797.1 AK118147 mRNA Translation: BAC42772.1 BT005511 mRNA Translation: AAO63931.1 |
PIRi | D84454 |
RefSeqi | NP_001324727.1, NM_001335215.1 NP_178497.2, NM_126449.5 |
3D structure databases
SMRi | Q8GXM8 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 345, 36 interactors |
IntActi | Q8GXM8, 35 interactors |
Proteomic databases
PaxDbi | Q8GXM8 |
PRIDEi | Q8GXM8 |
ProteomicsDBi | 221872 |
Genome annotation databases
EnsemblPlantsi | AT2G04080.1; AT2G04080.1; AT2G04080 |
GeneIDi | 814944 |
Gramenei | AT2G04080.1; AT2G04080.1; AT2G04080 |
KEGGi | ath:AT2G04080 |
Organism-specific databases
Araporti | AT2G04080 |
TAIRi | locus:2050185, AT2G04080 |
Phylogenomic databases
eggNOGi | KOG1347, Eukaryota |
HOGENOMi | CLU_012893_1_4_1 |
InParanoidi | Q8GXM8 |
OMAi | ATNIPIC |
OrthoDBi | 743037at2759 |
PhylomeDBi | Q8GXM8 |
Miscellaneous databases
PROi | PR:Q8GXM8 |
Gene expression databases
ExpressionAtlasi | Q8GXM8, baseline and differential |
Genevisiblei | Q8GXM8, AT |
Family and domain databases
InterProi | View protein in InterPro IPR002528, MATE_fam |
Pfami | View protein in Pfam PF01554, MatE, 2 hits |
TIGRFAMsi | TIGR00797, matE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DTX2_ARATH | |
Accessioni | Q8GXM8Primary (citable) accession number: Q8GXM8 Secondary accession number(s): Q9SIA2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 8, 2011 |
Last sequence update: | March 1, 2003 | |
Last modified: | December 2, 2020 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families