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UniProtKB - Q8GXK5 (EDL14_ARATH)
Protein
Sugar transporter ERD6-like 14
Gene
At4g04750
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Sugar transporter.
CuratedGO - Molecular functioni
- sugar transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Sugar transporter ERD6-like 14 |
Gene namesi | Ordered Locus Names:At4g04750 ORF Names:T4B21.10 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G04750 |
TAIRi | locus:2138927, AT4G04750 |
Subcellular locationi
Other locations
- Membrane By similarity; Multi-pass membrane protein By similarity
Mitochondrion
- mitochondrion Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 36 – 56 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 72 – 92 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 103 – 123 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 134 – 154 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 166 – 186 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 189 – 209 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Transmembranei | 271 – 291 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Transmembranei | 309 – 329 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Transmembranei | 337 – 357 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Transmembranei | 370 – 390 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Transmembranei | 410 – 430 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Transmembranei | 436 – 456 | Helical; Name=12Sequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000259864 | 1 – 482 | Sugar transporter ERD6-like 14Add BLAST | 482 |
Proteomic databases
PaxDbi | Q8GXK5 |
ProteomicsDBi | 224724 [Q8GXK5-1] |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8GXK5, baseline and differential |
Genevisiblei | Q8GXK5, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 11122, 26 interactors |
IntActi | Q8GXK5, 26 interactors |
STRINGi | 3702.AT4G04750.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q8GXK5 |
PhylomeDBi | Q8GXK5 |
Family and domain databases
CDDi | cd17358, MFS_GLUT6_8_Class3_like, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044775, MFS_ERD6/Tret1-like IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: Q8GXK5-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAEESLLPSH TEDVSASPNK SSSLLSEISN ASTRPFVLAF TVGSCGALSF
60 70 80 90 100
GCIVGYTAPT QSSIMKDLNL SIADFSFFGS ILTVGLILGA LICGKLADLV
110 120 130 140 150
GRVYTIWITN ILVLIGWLAI AFAKDVRLLD LGRLLQGISV GISSYLGPIY
160 170 180 190 200
ISELAPRNLR GAASSLMQLF VGVGLSAFYA LGTAVAWRSL AILGSIPSLV
210 220 230 240 250
VLPLLFFIPE SPRWLAKVGR EKEVEGVLLS LRGAKSDVSD EAATILEYTK
260 270 280 290 300
HVEQQDIDSR GFFKLFQRKY ALPLTIGVVL ISMPQLGGLN GYTFYTDTIF
310 320 330 340 350
TSTGVSSDIG FILTSIVQMT GGVLGVLLVD ISGRRSLLLF SQAGMFLGCL
360 370 380 390 400
ATAISFFLQK NNCWETGTPI MALISVMVYF GSYGLGMGPI PWIIASEIYP
410 420 430 440 450
VDVKGAAGTV CNLVTSISSW LVTYSFNFLL QWSSTGTFMM FATVMGLGFV
460 470 480
FTAKLVPETK GKSLEEIQSA FTDSTSEDST IF
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8B6H7 | A0A1P8B6H7_ARATH | Major facilitator superfamily prote... | At4g04750, T4B21.10, T4B21_10 | 526 | Annotation score: |
Sequence cautioni
The sequence AAD03450 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80840 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 269 | K → R in BAC42813 (PubMed:11910074).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_021552 | 304 – 482 | GVSSD…DSTIF → DDWRRFRCFACGYIRKTFSP TVFSSWNVLGLSSNSHFILL AEEQLLGNRNTNNGSH in isoform 2. CuratedAdd BLAST | 179 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF118223 Genomic DNA Translation: AAD03450.1 Sequence problems. AL161501 Genomic DNA Translation: CAB80840.1 Sequence problems. CP002687 Genomic DNA Translation: AEE82421.1 CP002687 Genomic DNA Translation: ANM67187.1 AK118190 mRNA Translation: BAC42813.1 |
PIRi | G85059 |
RefSeqi | NP_001329031.1, NM_001340507.1 [Q8GXK5-1] NP_192384.2, NM_116713.3 [Q8GXK5-1] |
Genome annotation databases
EnsemblPlantsi | AT4G04750.1; AT4G04750.1; AT4G04750 [Q8GXK5-1] AT4G04750.2; AT4G04750.2; AT4G04750 [Q8GXK5-1] |
GeneIDi | 825811 |
Gramenei | AT4G04750.1; AT4G04750.1; AT4G04750 [Q8GXK5-1] AT4G04750.2; AT4G04750.2; AT4G04750 [Q8GXK5-1] |
KEGGi | ath:AT4G04750 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF118223 Genomic DNA Translation: AAD03450.1 Sequence problems. AL161501 Genomic DNA Translation: CAB80840.1 Sequence problems. CP002687 Genomic DNA Translation: AEE82421.1 CP002687 Genomic DNA Translation: ANM67187.1 AK118190 mRNA Translation: BAC42813.1 |
PIRi | G85059 |
RefSeqi | NP_001329031.1, NM_001340507.1 [Q8GXK5-1] NP_192384.2, NM_116713.3 [Q8GXK5-1] |
3D structure databases
AlphaFoldDBi | Q8GXK5 |
SMRi | Q8GXK5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 11122, 26 interactors |
IntActi | Q8GXK5, 26 interactors |
STRINGi | 3702.AT4G04750.1 |
Proteomic databases
PaxDbi | Q8GXK5 |
ProteomicsDBi | 224724 [Q8GXK5-1] |
Genome annotation databases
EnsemblPlantsi | AT4G04750.1; AT4G04750.1; AT4G04750 [Q8GXK5-1] AT4G04750.2; AT4G04750.2; AT4G04750 [Q8GXK5-1] |
GeneIDi | 825811 |
Gramenei | AT4G04750.1; AT4G04750.1; AT4G04750 [Q8GXK5-1] AT4G04750.2; AT4G04750.2; AT4G04750 [Q8GXK5-1] |
KEGGi | ath:AT4G04750 |
Organism-specific databases
Araporti | AT4G04750 |
TAIRi | locus:2138927, AT4G04750 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_5_1 |
InParanoidi | Q8GXK5 |
PhylomeDBi | Q8GXK5 |
Miscellaneous databases
PROi | PR:Q8GXK5 |
Gene expression databases
ExpressionAtlasi | Q8GXK5, baseline and differential |
Genevisiblei | Q8GXK5, AT |
Family and domain databases
CDDi | cd17358, MFS_GLUT6_8_Class3_like, 1 hit |
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR044775, MFS_ERD6/Tret1-like IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | EDL14_ARATH | |
Accessioni | Q8GXK5Primary (citable) accession number: Q8GXK5 Secondary accession number(s): Q9M100, Q9ZS99 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 28, 2006 |
Last sequence update: | November 28, 2006 | |
Last modified: | May 25, 2022 | |
This is version 113 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families