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Entry version 92 (16 Oct 2019)
Sequence version 1 (01 Mar 2003)
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Protein

Cytochrome c oxidase assembly protein COX11, mitochondrial

Gene

COX11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCopper

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytochrome c oxidase assembly protein COX11, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COX11
Ordered Locus Names:At1g02410
ORF Names:T6A9.10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G02410

The Arabidopsis Information Resource

More...
TAIRi
locus:2204838 AT1G02410

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini81 – 92Mitochondrial matrixSequence analysisAdd BLAST12
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei93 – 115HelicalSequence analysisAdd BLAST23
Topological domaini116 – 287Mitochondrial intermembraneSequence analysisAdd BLAST172

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 80MitochondrionSequence analysisAdd BLAST80
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000041252681 – 287Cytochrome c oxidase assembly protein COX11, mitochondrialAdd BLAST207

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8GWR0

PRoteomics IDEntifications database

More...
PRIDEi
Q8GWR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8GWR0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8GWR0 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
24599, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q8GWR0, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT1G02410.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8GWR0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi56 – 61Poly-Ser6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2540 Eukaryota
COG3175 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000264965

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8GWR0

KEGG Orthology (KO)

More...
KOi
K02258

Identification of Orthologs from Complete Genome Data

More...
OMAi
YTHGACK

Database of Orthologous Groups

More...
OrthoDBi
1287401at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8GWR0

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.370.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00155 CtaG, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023471 CtaG/Cox11_dom_sf
IPR007533 Cyt_c_oxidase_assmbl_CtaG

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04442 CtaG_Cox11, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF110111 SSF110111, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q8GWR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSWSKACRGT RISSYLENLH RTSQYPRTIL CSRYYTHGAC KSNEHYLRSK
60 70 80 90 100
RVFWGSSSSW SLNSHSATAK SMLDSAHRQY STHSPSETKS QKMLYYLTAV
110 120 130 140 150
VFGMVGLTYA AVPLYRTFCQ ATGYGGTVQR KETVEEKIAR HSESGTVTER
160 170 180 190 200
EIVVQFNADV ADGMQWKFTP TQREVRVKPG ESALAFYTAE NKSSAPITGV
210 220 230 240 250
STYNVTPMKA GVYFNKIQCF CFEEQRLLPG EQIDMPVFFY IDPEFETDPR
260 270 280
MDGINNLILS YTFFKVSEEN TTETVNNNNS VPVQETN
Length:287
Mass (Da):32,605
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7221B3370A493F57
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAG00893 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC064879 Genomic DNA Translation: AAG00893.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27427.1
CP002684 Genomic DNA Translation: ANM59120.1
CP002684 Genomic DNA Translation: ANM59121.1
AK118687 mRNA Translation: BAC43281.1
BT005280 mRNA Translation: AAO63344.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E86154

NCBI Reference Sequences

More...
RefSeqi
NP_001321510.1, NM_001331337.1
NP_001321511.1, NM_001331336.1
NP_171743.1, NM_100122.6

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G02410.1; AT1G02410.1; AT1G02410
AT1G02410.2; AT1G02410.2; AT1G02410
AT1G02410.3; AT1G02410.3; AT1G02410

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
839364

Gramene; a comparative resource for plants

More...
Gramenei
AT1G02410.1; AT1G02410.1; AT1G02410
AT1G02410.2; AT1G02410.2; AT1G02410
AT1G02410.3; AT1G02410.3; AT1G02410

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G02410

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC064879 Genomic DNA Translation: AAG00893.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27427.1
CP002684 Genomic DNA Translation: ANM59120.1
CP002684 Genomic DNA Translation: ANM59121.1
AK118687 mRNA Translation: BAC43281.1
BT005280 mRNA Translation: AAO63344.1
PIRiE86154
RefSeqiNP_001321510.1, NM_001331337.1
NP_001321511.1, NM_001331336.1
NP_171743.1, NM_100122.6

3D structure databases

SMRiQ8GWR0
ModBaseiSearch...

Protein-protein interaction databases

BioGridi24599, 2 interactors
IntActiQ8GWR0, 2 interactors
STRINGi3702.AT1G02410.1

Proteomic databases

PaxDbiQ8GWR0
PRIDEiQ8GWR0

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
839364

Genome annotation databases

EnsemblPlantsiAT1G02410.1; AT1G02410.1; AT1G02410
AT1G02410.2; AT1G02410.2; AT1G02410
AT1G02410.3; AT1G02410.3; AT1G02410
GeneIDi839364
GrameneiAT1G02410.1; AT1G02410.1; AT1G02410
AT1G02410.2; AT1G02410.2; AT1G02410
AT1G02410.3; AT1G02410.3; AT1G02410
KEGGiath:AT1G02410

Organism-specific databases

AraportiAT1G02410
TAIRilocus:2204838 AT1G02410

Phylogenomic databases

eggNOGiKOG2540 Eukaryota
COG3175 LUCA
HOGENOMiHOG000264965
InParanoidiQ8GWR0
KOiK02258
OMAiYTHGACK
OrthoDBi1287401at2759
PhylomeDBiQ8GWR0

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8GWR0

Gene expression databases

ExpressionAtlasiQ8GWR0 baseline and differential
GenevisibleiQ8GWR0 AT

Family and domain databases

Gene3Di2.60.370.10, 1 hit
HAMAPiMF_00155 CtaG, 1 hit
InterProiView protein in InterPro
IPR023471 CtaG/Cox11_dom_sf
IPR007533 Cyt_c_oxidase_assmbl_CtaG
PfamiView protein in Pfam
PF04442 CtaG_Cox11, 1 hit
SUPFAMiSSF110111 SSF110111, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOX11_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8GWR0
Secondary accession number(s): Q9FZ20
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: March 1, 2003
Last modified: October 16, 2019
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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