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Protein

Guanylate kinase

Gene

gmk

Organism
Bifidobacterium longum (strain NCC 2705)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi15 – 22ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBLON206672:G1FZZ-70-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:BL0070
OrganismiBifidobacterium longum (strain NCC 2705)
Taxonomic identifieri206672 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000000439 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705031 – 196Guanylate kinaseAdd BLAST196

Interactioni

Protein-protein interaction databases

STRINGi206672.BL0070

Structurei

3D structure databases

ProteinModelPortaliQ8G813
SMRiQ8G813
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 191Guanylate kinase-likeUniRule annotationAdd BLAST184

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037640
KOiK00942
OMAiAGNYYGT
PhylomeDBiQ8G813

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8G813-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTENTHAGRL IVLTGPTAVG KGTVEAKLRA DHPEVWVSVS ATTRAPRPGE
60 70 80 90 100
VDGVNYWFLT EDEFLAREAA GEFLETAVVH GMAHYGTLLK PVEEHLAAGV
110 120 130 140 150
PTILEIDLQG ARRVKQRAAE LDLEVVYVFI APPSFEELER RLIGRGTETA
160 170 180 190
EQQARRLETA KVELAAESEF DVTIVNETVD QAAADLWSVI AKEYGL
Length:196
Mass (Da):21,492
Last modified:March 1, 2003 - v1
Checksum:i44C6E9CF88DC29A3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014295 Genomic DNA Translation: AAN23936.1
RefSeqiNP_695300.1, NC_004307.2
WP_007053267.1, NC_004307.2

Genome annotation databases

EnsemblBacteriaiAAN23936; AAN23936; BL0070
GeneIDi1023150
KEGGiblo:BL0070
PATRICifig|206672.9.peg.76

Similar proteinsi

Entry informationi

Entry nameiKGUA_BIFLO
AccessioniPrimary (citable) accession number: Q8G813
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: March 1, 2003
Last modified: March 28, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome