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Protein
Submitted name:

Beta-galactosidase

Gene

bgaA

Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi1495Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi1498Calcium 1Combined sources1
Metal bindingi1500Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi1509Calcium 1Combined sources1
Binding sitei1510GalactoseCombined sources1
Binding sitei1514GalactoseCombined sources1
Binding sitei1514N-acetyl-D-glucosamineCombined sources1
Binding sitei1601N-acetyl-D-glucosamineCombined sources1
Metal bindingi1636Calcium 1; via carbonyl oxygenCombined sources1
Metal bindingi1637Calcium 1Combined sources1
Metal bindingi1849Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi1852Calcium 2Combined sources1
Metal bindingi1854Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi1989Calcium 2; via carbonyl oxygenCombined sources1
Metal bindingi1990Calcium 2Combined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseSAAS annotationImported, Hydrolase
LigandCalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciSPNE171101:SPR0565-MONOMER

Protein family/group databases

CAZyiCBM71 Carbohydrate-Binding Module Family 71
GH2 Glycoside Hydrolase Family 2

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-galactosidaseImported (EC:3.2.1.23Imported)
Gene namesi
Name:bgaAImported
Ordered Locus Names:spr0565Imported
OrganismiStreptococcus pneumoniae (strain ATCC BAA-255 / R6)Imported
Taxonomic identifieri171101 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000586 Componenti: Chromosome

Subcellular locationi

  • cell wall SAAS annotation; Peptidoglycan-anchor SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

SecretedSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi171101.spr0565

Structurei

3D structure databases

ProteinModelPortaliQ8DQP4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2086 – 2162G5InterPro annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1488 – 1491Galactose bindingCombined sources4
Regioni1548 – 1551Galactose bindingCombined sources4

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.SAAS annotation

Phylogenomic databases

eggNOGiENOG4105CNT Bacteria
COG3250 LUCA
HOGENOMiHOG000285085
KOiK01190
OMAiMQYRTLA

Family and domain databases

Gene3Di2.60.120.260, 3 hits
2.60.40.10, 3 hits
InterProiView protein in InterPro
IPR036156 Beta-gal/glucu_dom_sf
IPR011081 Big_4
IPR032311 DUF4982
IPR011098 G5_dom
IPR008979 Galactose-bd-like_sf
IPR006101 Glyco_hydro_2
IPR006103 Glyco_hydro_2_cat
IPR006102 Glyco_hydro_2_Ig-like
IPR006104 Glyco_hydro_2_N
IPR017853 Glycoside_hydrolase_SF
IPR019948 Gram-positive_anchor
IPR013783 Ig-like_fold
IPR005877 YSIRK_signal_dom
PfamiView protein in Pfam
PF07532 Big_4, 4 hits
PF16355 DUF4982, 1 hit
PF07501 G5, 1 hit
PF00703 Glyco_hydro_2, 1 hit
PF02836 Glyco_hydro_2_C, 1 hit
PF02837 Glyco_hydro_2_N, 1 hit
PF00746 Gram_pos_anchor, 1 hit
PF04650 YSIRK_signal, 1 hit
PRINTSiPR00132 GLHYDRLASE2
SMARTiView protein in SMART
SM01208 G5, 1 hit
SUPFAMiSSF49303 SSF49303, 1 hit
SSF49785 SSF49785, 1 hit
SSF51445 SSF51445, 1 hit
TIGRFAMsiTIGR01168 YSIRK_signal, 1 hit
PROSITEiView protein in PROSITE
PS51109 G5, 1 hit

Sequencei

Sequence statusi: Complete.

Q8DQP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKGHWNRKR VYSIRKFAVG ACSVMIGTCA VLLGGNIAGE SVVYADETLI
60 70 80 90 100
THTAEKPKEE KMIVEEKADK ALETKNVVER TEQSEPSSTE AIASEKKEDE
110 120 130 140 150
AVTPKEEKVS AKPEEKAPRI ESQASSQEKP LKEDAKAVTN EEVNQMIENR
160 170 180 190 200
KVDFNQNWYF KLNANSKEAI KPDADVSTWK KLDLPYDWSI FNDFDHESPA
210 220 230 240 250
QNEGGQLNGG EAWYRKTFKL DEKDLKKNVR LTFDGVYMDS QVYVNGQLVG
260 270 280 290 300
HYPNGYNQFS YDITKYLYKD GRENVIAVHA VNKQPSSRWY SGSGIYRDVT
310 320 330 340 350
LQVTDKVHVE KNGTTILTPK LEEQQHGKVE THVTSKIVNT DDKDHELVAE
360 370 380 390 400
YQIVERGGHA VTGLVRTASR TLKAHESTSL DAILEVERPK LWTVLNDKPA
410 420 430 440 450
LYELITRVYR DGQLVDAKKD LFGYRYYHWT PNEGFSLNGE RIKFHGVSLH
460 470 480 490 500
HDHGALGAEE NYKAEYRRLK QMKEMGVNSI RTTHNPASEQ TLQIAAELGL
510 520 530 540 550
LVQEEAFDTW YGGKKPYDYG RFFEKDATHP EARKGEKWSD FDLRTMVERG
560 570 580 590 600
KNNPAIFMWS IGNEIGEANG DAHSLATVKR LVKVIKDVDK TRYVTMGADK
610 620 630 640 650
FRFGNGSGGH EKIADELDAV GFNYSEDNYK ALRAKHPKWL IYGSETSSAT
660 670 680 690 700
RTRGSYYRPE RELKHSNGPE RNYEQSDYGN DRVGWGKTAT ASWTFDRDNA
710 720 730 740 750
GYAGQFIWTG TDYIGEPTPW HNQNQTPVKS SYFGIVDTAG IPKHDFYLYQ
760 770 780 790 800
SQWVSVKKKP MVHLLPHWNW ENKELASKVA DSEGKIPVRA YSNASSVELF
810 820 830 840 850
LNGKSLGLKT FNKKQTSDGR TYQEGANANE LYLEWKVAYQ PGTLEAIARD
860 870 880 890 900
ESGKEIARDK ITTAGKPAAV RLIKEDHAIA ADGKDLTYIY YEIVDSQGNV
910 920 930 940 950
VPTANNLVRF QLHGQGQLVG VDNGEQASRE RYKAQADGSW IRKAFNGKGV
960 970 980 990 1000
AIVKSTEQAG KFTLTAHSDL LKSNQVTVFT GKKEGQEKTV LGTEVPKVQT
1010 1020 1030 1040 1050
IIGEAPEMPT TVPFVYSDGS RAERPVTWSL VDVSKPGIVT VKGMADGREV
1060 1070 1080 1090 1100
EARVEVIALK SELPVVKRIA PNTNLNSVDK SVSYVLTDGS VQEYEVDKWE
1110 1120 1130 1140 1150
IAEEDKAKLA IPGSRIQATG YLEGQPIHAT LVVEEGNPAA PVVPTVTVGG
1160 1170 1180 1190 1200
EAVTGLTSRQ PMQYRTLSYG AQLPEVTASA ENADVTVLQA SAANGMRASI
1210 1220 1230 1240 1250
FIQPKDGGPL QTYAIQFLEE APKIAHLSLQ VEKADSLKED QTVKLSVRAH
1260 1270 1280 1290 1300
YQDGTQAVLP ADKVTFSTSG EGEVAIRKGM LELHKPGAVT LNAEYEGAKG
1310 1320 1330 1340 1350
QVELTIQANT EKKIAQSIRP VNVVTDLHQE PSLPATVTVE YDKGFPKTHK
1360 1370 1380 1390 1400
VTWQAIPKEK LDSYQIFEVL GKVEGIDLEA RAKVSVEGIV SVEEVSVTTP
1410 1420 1430 1440 1450
IAEAPQLPES VRTYDSNGHV SSAKVAWDAI RPEQYAKEGV FTVNGRLEGT
1460 1470 1480 1490 1500
QLTTKLHVRV SAQTEQGANI SDQWTGSELP LAFASDSNPS DPVSNVNDKL
1510 1520 1530 1540 1550
ISYNNQPANR WTNWNRSNPE ASVGVLFGDS GILSKRSVDN LSVGFHEDHG
1560 1570 1580 1590 1600
VGAPKSYVIE YYVGKTVPTA PKNPSFVGNE DHVFNDSANW KPVTNLKAPA
1610 1620 1630 1640 1650
QLKAGEMNHF SFDKVETYAI RIRMVKADNK RGTSITEVQI FAKQVAAAKQ
1660 1670 1680 1690 1700
GQTRIQVDGK DLANFNPDLT DYYLESVDGK VPAVTANVSN NGLATVVPSV
1710 1720 1730 1740 1750
REGEPVRVIA KAENGDILGE YRLHFTKDKN LLSHKPVAAV KQARLLQVGQ
1760 1770 1780 1790 1800
ALELPTKVPV YFTGKDGYET KDLTVEWEEV PAENLTKAGQ FTVRGRVLGS
1810 1820 1830 1840 1850
NLVAEVTVRV TDKLGETLSD NPNYDENSNQ AFASATNDID KNSHDRVDYL
1860 1870 1880 1890 1900
NDGDHSENRR WTNWSPTPSS NPEVSAGVIF RENGKIVERT VAQAKLHFFA
1910 1920 1930 1940 1950
DSGTDAPSKL VLERYVGPGF EVPTYYSNYQ AYESGHPFNN PENWEAVPYR
1960 1970 1980 1990 2000
ADKDIAAGDE INVTFKAVKA KVMRWRMERK ADKSGVAMIE MTFLAPSELP
2010 2020 2030 2040 2050
QESTQSKILV DGKELADFAE NRQDYQITYK GQRPKVSVEE NNQVASTVVD
2060 2070 2080 2090 2100
SGEDSLPVLV RLVSESGKQV KEYRIQLTKE KPVSAVQEDL PKLEFVEKDL
2110 2120 2130 2140 2150
AYKTVEKKDS TLYLGETRVE QEGKVGKERI FTVINPDGSK EEKLREVVEV
2160 2170 2180 2190 2200
PTDRIVLVGT KPVAQEAKKP QVSEKADTKP IDSSEADQTN KAQLPNTGSA
2210 2220
ASQAAVAAGL ALLGLSAGLV VTKGKKED
Length:2,228
Mass (Da):246,782
Last modified:March 1, 2003 - v1
Checksum:i5E3323A89F8E561C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE007317 Genomic DNA Translation: AAK99369.1
PIRiE97942
RefSeqiNP_358159.1, NC_003098.1
WP_000515226.1, NC_003098.1

Genome annotation databases

EnsemblBacteriaiAAK99369; AAK99369; spr0565
GeneIDi933305
KEGGispr:spr0565
PATRICifig|171101.6.peg.629

Similar proteinsi

Entry informationi

Entry nameiQ8DQP4_STRR6
AccessioniPrimary (citable) accession number: Q8DQP4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: July 18, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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