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Protein

Ras association domain-containing protein 8

Gene

Rassf8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Ras association domain-containing protein 8
Alternative name(s):
Carcinoma-associated protein HOJ-1 homolog
Gene namesi
Name:Rassf8
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1918573 Rassf8

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898411 – 419Ras association domain-containing protein 8Add BLAST419

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei105PhosphoserineBy similarity1
Modified residuei129PhosphoserineBy similarity1
Modified residuei131PhosphothreonineBy similarity1
Modified residuei387PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8CJ96
PaxDbiQ8CJ96
PeptideAtlasiQ8CJ96
PRIDEiQ8CJ96

PTM databases

iPTMnetiQ8CJ96
PhosphoSitePlusiQ8CJ96

Expressioni

Gene expression databases

BgeeiENSMUSG00000030259 Expressed in 266 organ(s), highest expression level in pineal body
ExpressionAtlasiQ8CJ96 baseline and differential
GenevisibleiQ8CJ96 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000032388

Structurei

3D structure databases

ProteinModelPortaliQ8CJ96
SMRiQ8CJ96
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 82Ras-associatingPROSITE-ProRule annotationAdd BLAST82

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi181 – 301Glu-richAdd BLAST121

Phylogenomic databases

eggNOGiKOG1574 Eukaryota
ENOG410XPWB LUCA
GeneTreeiENSGT00530000063648
HOGENOMiHOG000013031
HOVERGENiHBG050971
InParanoidiQ8CJ96
KOiK09855
OMAiAQIQTME
OrthoDBiEOG091G0RF3
PhylomeDBiQ8CJ96
TreeFamiTF318385

Family and domain databases

InterProiView protein in InterPro
IPR033593 N-RASSF
IPR000159 RA_dom
IPR033632 RASSF8
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR15286 PTHR15286, 1 hit
PTHR15286:SF9 PTHR15286:SF9, 1 hit
PfamiView protein in Pfam
PF00788 RA, 1 hit
SMARTiView protein in SMART
SM00314 RA, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50200 RA, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.iShow all

Q8CJ96-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELKVWVDGV QRIVCGVTEV TTCQEVVIAL AQAIGRTGRY TLIEKWRDTE
60 70 80 90 100
RHLAPHENPI VSLNKWGQYA SDVQLILRRT GPSLSERPTS DSVARIPERT
110 120 130 140 150
LYRQSLPPLA KLRPQADKSI RRREPKRKSL TFTGGAKGLT DIFGKGKETE
160 170 180 190 200
FRQKVLSNCR ATAEELKRLI RLQTGKLQAI EKQLESSEAE IRFWEQKYSC
210 220 230 240 250
SLEEEIVRLE QRIKRNDVEI EEEEFWENEL QIEQENEKQL QDQLEEIRQK
260 270 280 290 300
VTDCEGRLKD YLAQIHTMES GLQAEKLHRE VQEAQVNEEE VKGKIEKVKG
310 320 330 340 350
EMDLQGQQSL RLENGIRAVE RSLGQATKRL QDKEQELEQL TKELRQVNLQ
360 370 380 390 400
QFIQQTGTKV TVLPAEPTEI EASQADIETE APFQSGSLKR PGSSRQLPSN
410
LRILQNPVSS GFNPEGIYV
Length:419
Mass (Da):48,103
Last modified:March 1, 2003 - v1
Checksum:iA809CFFE0AE62597
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QA00E9QA00_MOUSE
Ras association domain-containing p...
Rassf8
79Annotation score:
F7BB71F7BB71_MOUSE
Ras association domain-containing p...
Rassf8
102Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti173Q → E in BAB30637 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF424737 mRNA Translation: AAN28310.1
BC115779 mRNA Translation: AAI15780.1
BC117546 mRNA Translation: AAI17547.1
AK017214 mRNA Translation: BAB30637.1
AK031980 mRNA Translation: BAC27637.1
CCDSiCCDS20696.1
RefSeqiNP_082036.1, NM_027760.2
XP_011239900.1, XM_011241598.1
XP_011239901.1, XM_011241599.1
XP_011239902.1, XM_011241600.2
UniGeneiMm.158669
Mm.444985

Genome annotation databases

EnsembliENSMUST00000032388; ENSMUSP00000032388; ENSMUSG00000030259
ENSMUST00000111704; ENSMUSP00000107333; ENSMUSG00000030259
GeneIDi71323
KEGGimmu:71323
UCSCiuc009err.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRASF8_MOUSE
AccessioniPrimary (citable) accession number: Q8CJ96
Secondary accession number(s): Q149Q5, Q8CCW4, Q9CU91
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 21, 2005
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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