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UniProtKB - Q8CJ91 (C209B_MOUSE)

Entry version 133 (22 Apr 2020)
Sequence version 2 (13 Apr 2004)
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Protein

CD209 antigen-like protein B

Gene

Cd209b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.

Miscellaneous

In vitro, is a receptor for HIV-1, HIV-2 and SIV, but does not transmit virus to permissive T-cells under the conditions tested.

Caution

In mouse, 5 genes homologous to human CD209/DC-SIGN and CD209L/DC-SIGNR have been identified.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi285CalciumBy similarity1
Metal bindingi287CalciumBy similarity1
Metal bindingi289Calcium; via carbonyl oxygenBy similarity1
Metal bindingi292CalciumBy similarity1
Metal bindingi303CalciumBy similarity1
Metal bindingi304CalciumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processEndocytosis
LigandCalcium, Lectin, Mannose-binding, Metal-binding

Protein family/group databases

UniLectin database of carbohydrate-binding proteins

More...UniLectini		Q8CJ91

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
CD209 antigen-like protein B
Alternative name(s):
DC-SIGN-related protein 1
Short name:
DC-SIGNR1
OtB7
CD_antigen: CD209
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cd209b
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1916415 Cd209b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 52CytoplasmicSequence analysisAdd BLAST52
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei53 – 73Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini74 – 325ExtracellularSequence analysisAdd BLAST252

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000466051 – 325CD209 antigen-like protein BAdd BLAST325

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi112N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi141N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi195 ↔ 206PROSITE-ProRule annotation
Disulfide bondi223 ↔ 315PROSITE-ProRule annotation
Disulfide bondi294 ↔ 307PROSITE-ProRule annotation
Glycosylationi303N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8CJ91

PRoteomics IDEntifications database

More...PRIDEi		Q8CJ91

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8CJ91

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in skin, spleen and lung, probably in a subset of dendritic cells. Detected in spleen extrafollicular paracortical areas including the red pulp and marginal zones, and at lower levels, in the follicular area. Detected in skin suprabasal areas adjacent to the epidermis and in epidermal cell layer.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000065987 Expressed in mesenteric lymph node and 47 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8CJ91 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8CJ91 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Database of interacting proteins

More...DIPi		DIP-61328N

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000081104

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8CJ91 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1325
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8CJ91

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini201 – 316C-type lectinPROSITE-ProRule annotationAdd BLAST116

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IS3Z Eukaryota
ENOG410YSMB LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155012

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_049894_7_3_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8CJ91

KEGG Orthology (KO)

More...KOi		K06563

Identification of Orthologs from Complete Genome Data

More...OMAi		NPFKAWN

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8CJ91

TreeFam database of animal gene trees

More...TreeFami		TF333341

Family and domain databases

Conserved Domains Database

More...CDDi		cd03590 CLECT_DC-SIGN_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR033989 CD209-like_CTLD
IPR016187 CTDL_fold

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00059 Lectin_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00034 CLECT, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56436 SSF56436, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CJ91-1) [UniParc]FASTAAdd to basket
Also known as: alpha

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSDSTEAKMQ PLSSMDDDEL MVSGSRYSIK SSRLRPNSGI KCLAGCSGHS 
        60         70         80         90        100
QVPLVLQLLS FLFLAGLLLI ILFQVSKTPN TERQKEQEKI LQELTQLTDE 
       110        120        130        140        150
LTSRIPISQG KNESMQAKIT EQLMQLKTEL LSRIPIFQGQ NESIQEKISE 
       160        170        180        190        200
QLMQLKAELL SKISSFPVKD DSKQEKIYQQ LVQMKTELFR LCRLCPWDWT 
       210        220        230        240        250
FLLGNCYFFS KSQRNWNDAV TACKEVKAQL VIINSDEEQT FLQQTSKAKG 
       260        270        280        290        300
PTWMGLSDLK KEATWLWVDG STLSSRFQKY WNRGEPNNIG EEDCVEFAGD 
       310        320 
GWNDSKCELK KFWICKKSAT PCTEG
Length:325
Mass (Da):37,112
Last modified:April 13, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9C9388407C247CA4
GO
Isoform 2 (identifier: Q8CJ91-2) [UniParc]FASTAAdd to basket
Also known as: beta, TM-less

The sequence of this isoform differs from the canonical sequence as follows:
     45-74: Missing.

Show »
Length:295
Mass (Da):33,889
Checksum:iA491F7D3551A91D0
GO
Isoform 3 (identifier: Q8CJ91-3) [UniParc]FASTAAdd to basket
Also known as: gamma

The sequence of this isoform differs from the canonical sequence as follows:
     45-74: Missing.
     275-275: S → SSRPRHAPISRGRPIYNMHSGR

Show »
Length:316
Mass (Da):36,316
Checksum:iE43D6B00F58AA784
GO
Isoform 4 (identifier: Q8CJ91-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-183: Missing.

Show »
Length:142
Mass (Da):16,471
Checksum:i0CBB36A383D887EF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8CJ85Q8CJ85_MOUSE
CD209 antigen-like protein B
Cd209b
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB25166 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti71I → V in AAN75588 (PubMed:12137941).Curated1
Sequence conflicti87Q → P in AAN75589 (PubMed:12137941).Curated1
Sequence conflicti112N → D in AAN75586 (PubMed:12137941).Curated1
Sequence conflicti124M → T in AAN75585 (PubMed:12137941).Curated1
Sequence conflicti138Q → R in AAN75588 (PubMed:12137941).Curated1
Sequence conflicti163I → V in AAN75586 (PubMed:12137941).Curated1
Sequence conflicti226V → A in AAN75588 (PubMed:12137941).Curated1
Sequence conflicti229Q → R in AAN75589 (PubMed:12137941).Curated1
Sequence conflicti232I → T in AAN75587 (PubMed:12137941).Curated1
Sequence conflicti235S → G in AAN75587 (PubMed:12137941).Curated1
Sequence conflicti267W → R in AAN75589 (PubMed:12137941).Curated1
Sequence conflicti308E → G in AAN75585 (PubMed:12137941).Curated1
Sequence conflicti312F → L in AAN75597 (PubMed:12137941).Curated1
Sequence conflicti321 – 325PCTEG → HA in AAN75590 (PubMed:12137941).Curated5
Sequence conflicti323 – 325TEG → P in AAN75585 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75586 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75587 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75588 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75589 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75591 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75592 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75593 (PubMed:12137941).Curated3
Sequence conflicti323 – 325TEG → P in AAN75594 (PubMed:12137941).Curated3

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0100681 – 183Missing in isoform 4. 1 PublicationAdd BLAST183
Alternative sequenceiVSP_01006945 – 74Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST30
Alternative sequenceiVSP_010070275S → SSRPRHAPISRGRPIYNMHS GR in isoform 3. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF373409 mRNA Translation: AAL13235.1
AF374471 mRNA Translation: AAL27540.1
AF424790 mRNA Translation: AAN75585.1
AF424791 mRNA Translation: AAN75586.1
AF424792 mRNA Translation: AAN75587.1
AF424793 mRNA Translation: AAN75588.1
AF424794 mRNA Translation: AAN75589.1
AF424795 mRNA Translation: AAN75590.1
AF424797 mRNA Translation: AAN75592.1
AF424798 mRNA Translation: AAN75593.1
AF424796 mRNA Translation: AAN75591.1
AF424799 mRNA Translation: AAN75594.1
AF424800 mRNA Translation: AAN75595.1
AF424801 mRNA Translation: AAN75596.1
AF424802 mRNA Translation: AAN75597.1
AF422108 mRNA Translation: AAN31450.1
AK007656 mRNA Translation: BAB25166.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS22076.1 [Q8CJ91-2]
CCDS22077.1 [Q8CJ91-1]
CCDS72089.1 [Q8CJ91-3]

NCBI Reference Sequences

More...RefSeqi		NP_001032889.3, NM_001037800.3 [Q8CJ91-2]
NP_001274140.1, NM_001287211.1 [Q8CJ91-3]
NP_081248.4, NM_026972.5 [Q8CJ91-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000084086; ENSMUSP00000081104; ENSMUSG00000065987 [Q8CJ91-1]
ENSMUST00000171635; ENSMUSP00000126070; ENSMUSG00000065987 [Q8CJ91-2]
ENSMUST00000188386; ENSMUSP00000140695; ENSMUSG00000065987 [Q8CJ91-3]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		69165

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:69165

UCSC genome browser

More...UCSCi		uc009ksu.2 mouse [Q8CJ91-1]
uc009ksv.2 mouse [Q8CJ91-2]
uc012fyw.2 mouse [Q8CJ91-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

<p>This subsection of the <a href="http://www.uniprot.org/manual/cross%5Freferences%5Fsection">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Functional Glycomics Gateway - Glycan Binding

SIGNR1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF373409 mRNA Translation: AAL13235.1
AF374471 mRNA Translation: AAL27540.1
AF424790 mRNA Translation: AAN75585.1
AF424791 mRNA Translation: AAN75586.1
AF424792 mRNA Translation: AAN75587.1
AF424793 mRNA Translation: AAN75588.1
AF424794 mRNA Translation: AAN75589.1
AF424795 mRNA Translation: AAN75590.1
AF424797 mRNA Translation: AAN75592.1
AF424798 mRNA Translation: AAN75593.1
AF424796 mRNA Translation: AAN75591.1
AF424799 mRNA Translation: AAN75594.1
AF424800 mRNA Translation: AAN75595.1
AF424801 mRNA Translation: AAN75596.1
AF424802 mRNA Translation: AAN75597.1
AF422108 mRNA Translation: AAN31450.1
AK007656 mRNA Translation: BAB25166.1 Different initiation.
CCDSiCCDS22076.1 [Q8CJ91-2]
CCDS22077.1 [Q8CJ91-1]
CCDS72089.1 [Q8CJ91-3]
RefSeqiNP_001032889.3, NM_001037800.3 [Q8CJ91-2]
NP_001274140.1, NM_001287211.1 [Q8CJ91-3]
NP_081248.4, NM_026972.5 [Q8CJ91-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ZHGX-ray1.87A/B/C191-325[»]
D190-325[»]
4C9FX-ray2.60A/B/C/D191-323[»]
4CAJX-ray2.19A/B/C/D191-325[»]
SMRiQ8CJ91
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

DIPiDIP-61328N
STRINGi10090.ENSMUSP00000081104

Protein family/group databases

UniLectiniQ8CJ91

PTM databases

PhosphoSitePlusiQ8CJ91

Proteomic databases

PaxDbiQ8CJ91
PRIDEiQ8CJ91

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		69165

Genome annotation databases

EnsembliENSMUST00000084086; ENSMUSP00000081104; ENSMUSG00000065987 [Q8CJ91-1]
ENSMUST00000171635; ENSMUSP00000126070; ENSMUSG00000065987 [Q8CJ91-2]
ENSMUST00000188386; ENSMUSP00000140695; ENSMUSG00000065987 [Q8CJ91-3]
GeneIDi69165
KEGGimmu:69165
UCSCiuc009ksu.2 mouse [Q8CJ91-1]
uc009ksv.2 mouse [Q8CJ91-2]
uc012fyw.2 mouse [Q8CJ91-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		69165
MGIiMGI:1916415 Cd209b

Phylogenomic databases

eggNOGiENOG410IS3Z Eukaryota
ENOG410YSMB LUCA
GeneTreeiENSGT00940000155012
HOGENOMiCLU_049894_7_3_1
InParanoidiQ8CJ91
KOiK06563
OMAiNPFKAWN
PhylomeDBiQ8CJ91
TreeFamiTF333341

Miscellaneous databases

Protein Ontology

More...PROi		PR:Q8CJ91
RNActiQ8CJ91 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000065987 Expressed in mesenteric lymph node and 47 other tissues
ExpressionAtlasiQ8CJ91 baseline and differential
GenevisibleiQ8CJ91 MM

Family and domain databases

CDDicd03590 CLECT_DC-SIGN_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR033989 CD209-like_CTLD
IPR016187 CTDL_fold
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC209B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CJ91
Secondary accession number(s): Q8BGZ0
, Q8BHK7, Q8CJ86, Q8CJ87, Q8CJ88, Q8CJ89, Q8CJ90, Q8CJ92, Q8CJ93, Q8CJ94, Q91ZW4, Q91ZX0, Q9D8V4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: April 13, 2004
Last modified: April 22, 2020
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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