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Entry version 131 (10 Feb 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Integrator complex subunit 4

Gene

Ints4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6807505, RNA polymerase II transcribes snRNA genes

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Integrator complex subunit 4
Short name:
Int4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ints4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917164, Ints4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002595391 – 964Integrator complex subunit 4Add BLAST964

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei27N6-acetyllysineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki792Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linki792Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8CIM8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CIM8

PeptideAtlas

More...
PeptideAtlasi
Q8CIM8

PRoteomics IDEntifications database

More...
PRIDEi
Q8CIM8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CIM8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CIM8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025133, Expressed in undifferentiated genital tubercle and 283 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8CIM8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
221739, 20 interactors

Protein interaction database and analysis system

More...
IntActi
Q8CIM8, 10 interactors

Molecular INTeraction database

More...
MINTi
Q8CIM8

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000026126

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CIM8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati67 – 106HEAT 1Add BLAST40
Repeati146 – 184HEAT 2Add BLAST39
Repeati191 – 229HEAT 3Add BLAST39
Repeati230 – 264HEAT 4Add BLAST35
Repeati278 – 314HEAT 5Add BLAST37
Repeati370 – 406HEAT 6Add BLAST37
Repeati407 – 445HEAT 7Add BLAST39
Repeati447 – 485HEAT 8Add BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Integrator subunit 4 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2259, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010128

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012910_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CIM8

Identification of Orthologs from Complete Genome Data

More...
OMAi
HVQDPQG

Database of Orthologous Groups

More...
OrthoDBi
256550at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CIM8

TreeFam database of animal gene trees

More...
TreeFami
TF315047

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR026003, Cohesin_HEAT

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12765, Cohesin_HEAT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CIM8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAHLKKRVY EEFTKVVQQQ QEEIATKKLR LTKPSKSAAL HIDLCKATSP
60 70 80 90 100
ADALQYLLQF ARKPVEAESV EGVVRILLEH YYKENDPSVR LKIASLLGLL
110 120 130 140 150
SKTAGFSPDC IMDDAINILQ NEKSHQVLAQ LLDTLLAIGS KLPENQATQV
160 170 180 190 200
RLVDVACKHL TDTSHGVRNK CLQLLGNLGS LEKSVTKDTE GSAARDVQKI
210 220 230 240 250
IGDHFSDQDP RVRTAAIKAM LQLHERGLKL HQTIYNQACK LLSDDYEQVR
260 270 280 290 300
SAAVQLIWVV SQLYPESIVP IPSSNEEIRL VDDAFGKICH MVSDGSWVVR
310 320 330 340 350
VQAAKLLGSM EQVSSHFLEQ TLDKKLMSDL RRKRTAHERA KELYSSGEFS
360 370 380 390 400
SGRKWGDDAP KEEIDTGAVN LIESGACGAF VHGLEDEMYE VRIAAVEALC
410 420 430 440 450
MLAQSSPSFA EKCLDFLVDM FNDEIEEVRL QSIHTMRKIS NNITLREDQL
460 470 480 490 500
DTVLAVLEDS SRDIREALHE LLCCTNVSTK EGIHLALVEL LKNLTKYPTD
510 520 530 540 550
RDSIWKCLKF LGSRHPTLVL PLVPELLSTH PFFDTAEPDM DDPAYIAVLV
560 570 580 590 600
LIFNAAKTCP TMPALFSDHT LRHYAYLRDS LSHLVPALRL PGRKLVSSTV
610 620 630 640 650
PSNITPHEDP SQQFLQQSLE RVYSVQHLDP QGAQELLEFT IRDLQRLGEL
660 670 680 690 700
QSELAGVADF SATYLQCQLL LIKALQEKLW NVAAPLYLKQ SDLASAAAKQ
710 720 730 740 750
IMEETYKMEF MYSGVENKQV VIIQHMRLQA KALQLIVTAR TTRGVDPLFG
760 770 780 790 800
MCEKFLQEVD FFQRCFIADL PHLQDSFVDK LLDLMPRLMA SKPVEVIKIL
810 820 830 840 850
QTMLRQSTFL HLPLPEQIHK ASATIIEPAG ESDNPLRFTS GLVVALDVDA
860 870 880 890 900
TLEHVQDPQN TVKVQVLYPD GQAQMIHPKP ADFRNPGPGR HRLLTQVYLS
910 920 930 940 950
HTAWTEPCQV EVRLLLAYNS GARIPKSPWL EGSEMSPQVE TSIEGTIPFS
960
KPVKVYIMPK PARR
Length:964
Mass (Da):108,193
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF00ADA2FF1076FF
GO
Isoform 2 (identifier: Q8CIM8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     507-964: Missing.

Show »
Length:506
Mass (Da):56,643
Checksum:iF9E9574E3DC335BE
GO
Isoform 3 (identifier: Q8CIM8-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     221-223: LQL → VTG
     224-964: Missing.

Show »
Length:223
Mass (Da):24,565
Checksum:i6D48C272553B4C8C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0U1RPX1A0A0U1RPX1_MOUSE
Integrator complex subunit 4
Ints4
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH13813 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAE37328 differs from that shown. Reason: Frameshift.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_021454221 – 223LQL → VTG in isoform 3. 1 Publication3
Alternative sequenceiVSP_021455224 – 964Missing in isoform 3. 1 PublicationAdd BLAST741
Alternative sequenceiVSP_021456507 – 964Missing in isoform 2. 1 PublicationAdd BLAST458

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK011676 mRNA Translation: BAB27773.1
AK088635 mRNA Translation: BAC40468.1
AK163383 mRNA Translation: BAE37328.1 Frameshift.
BC013710 mRNA Translation: AAH13710.1
BC013813 mRNA Translation: AAH13813.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS21460.1 [Q8CIM8-1]

NCBI Reference Sequences

More...
RefSeqi
NP_081532.1, NM_027256.2 [Q8CIM8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000026126; ENSMUSP00000026126; ENSMUSG00000025133 [Q8CIM8-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101861

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:101861

UCSC genome browser

More...
UCSCi
uc009ijg.2, mouse [Q8CIM8-3]
uc009ijh.2, mouse [Q8CIM8-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011676 mRNA Translation: BAB27773.1
AK088635 mRNA Translation: BAC40468.1
AK163383 mRNA Translation: BAE37328.1 Frameshift.
BC013710 mRNA Translation: AAH13710.1
BC013813 mRNA Translation: AAH13813.1 Different initiation.
CCDSiCCDS21460.1 [Q8CIM8-1]
RefSeqiNP_081532.1, NM_027256.2 [Q8CIM8-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi221739, 20 interactors
IntActiQ8CIM8, 10 interactors
MINTiQ8CIM8
STRINGi10090.ENSMUSP00000026126

PTM databases

iPTMnetiQ8CIM8
PhosphoSitePlusiQ8CIM8

Proteomic databases

EPDiQ8CIM8
PaxDbiQ8CIM8
PeptideAtlasiQ8CIM8
PRIDEiQ8CIM8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
31280, 124 antibodies

Genome annotation databases

EnsembliENSMUST00000026126; ENSMUSP00000026126; ENSMUSG00000025133 [Q8CIM8-1]
GeneIDi101861
KEGGimmu:101861
UCSCiuc009ijg.2, mouse [Q8CIM8-3]
uc009ijh.2, mouse [Q8CIM8-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92105
MGIiMGI:1917164, Ints4

Phylogenomic databases

eggNOGiKOG2259, Eukaryota
GeneTreeiENSGT00390000010128
HOGENOMiCLU_012910_1_0_1
InParanoidiQ8CIM8
OMAiHVQDPQG
OrthoDBi256550at2759
PhylomeDBiQ8CIM8
TreeFamiTF315047

Enzyme and pathway databases

ReactomeiR-MMU-6807505, RNA polymerase II transcribes snRNA genes

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
101861, 9 hits in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ints4, mouse

Protein Ontology

More...
PROi
PR:Q8CIM8
RNActiQ8CIM8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000025133, Expressed in undifferentiated genital tubercle and 283 other tissues
GenevisibleiQ8CIM8, MM

Family and domain databases

Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989, ARM-like
IPR016024, ARM-type_fold
IPR026003, Cohesin_HEAT
PfamiView protein in Pfam
PF12765, Cohesin_HEAT, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiINT4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CIM8
Secondary accession number(s): Q3TQQ4
, Q8C2H1, Q91YV5, Q9CSY4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2003
Last modified: February 10, 2021
This is version 131 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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