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Entry version 140 (29 Sep 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Protein mono-ADP-ribosyltransferase PARP10

Gene

Parp10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate and aspartate residues on target proteins. In contrast to PARP1 and PARP2, it is not able to mediate poly-ADP-ribosylation. Catalyzes mono-ADP-ribosylation of GSK3B, leading to negatively regulate GSK3B kinase activity. Involved in translesion DNA synthesis in response to DNA damage via its interaction with PCNA.

By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processDNA damage, DNA repair
LigandNAD

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-197264, Nicotinamide salvaging

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein mono-ADP-ribosyltransferase PARP10Curated (EC:2.4.2.-By similarity)
Alternative name(s):
ADP-ribosyltransferase diphtheria toxin-like 10By similarity
Short name:
ARTD10By similarity
Poly [ADP-ribose] polymerase 10By similarity
Short name:
PARP-10By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Parp10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3712326, Parp10

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000063268

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004461721 – 960Protein mono-ADP-ribosyltransferase PARP10Add BLAST960

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei103ADP-ribosyl glutamic acidBy similarity1
Modified residuei381PhosphoserineBy similarity1
Modified residuei388PhosphoserineBy similarity1
Modified residuei617PhosphoserineBy similarity1
Modified residuei831ADP-ribosyl glutamic acidBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Stimulated through its phosphorylation by CDK2. Acquires CDK-dependent phosphorylation through late-G1 to S phase, and from prometaphase to cytokinesis in the nucleolar organizing regions. Phosphorylation is suppressed in growth-arrested cells.By similarity
Auto-mono-ADP-ribosylated on glutamate and lysine residues.By similarity

Keywords - PTMi

ADP-ribosylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8CIE4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8CIE4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CIE4

PRoteomics IDEntifications database

More...
PRIDEi
Q8CIE4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
334670
357507

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CIE4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CIE4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000063268, Expressed in adult mammalian kidney and 159 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with MYC.

Interacts with PARP14.

Interacts (via-PIP box and ubiquitin-interacting motifs) with PCNA.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000129765

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CIE4, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CIE4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini755 – 960PARP catalyticPROSITE-ProRule annotationAdd BLAST206

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni325 – 346DisorderedSequence analysisAdd BLAST22
Regioni553 – 576DisorderedSequence analysisAdd BLAST24
Regioni649 – 856Myc bindingBy similarityAdd BLAST208

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi604 – 621Ubiquitin-interactingBy similarityAdd BLAST18
Motifi780 – 787PIP-boxBy similarity8

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi553 – 573Basic and acidic residuesSequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The PIP-box mediates the interaction with PCNA.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ARTD/PARP family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R572, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162035

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_014825_3_2_1

Identification of Orthologs from Complete Genome Data

More...
OMAi
QAFYNTL

Database of Orthologous Groups

More...
OrthoDBi
681829at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CIE4

TreeFam database of animal gene trees

More...
TreeFami
TF328965

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12547, RRM1_2_PAR10, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR034464, PAR10_RRM1_2
IPR012317, Poly(ADP-ribose)pol_cat_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00644, PARP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51059, PARP_CATALYTIC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8CIE4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAEVEAGAAL ELRGLPPEIP DELITLYFEN HRRSGGGLLL SWQRLGCGGV
60 70 80 90 100
LIFQDPADAK RVLAQAEHRL HGVRLSLRPA PPRAPERVLL QHLPPGTSPL
110 120 130 140 150
SLEQHVQALL GAAGHPVQTC HALASPRQDC ALVQLSTPLS EAEVSALAEQ
160 170 180 190 200
ARNLPLNGAT VSLAWVPQTR AVRVVDSASP VDLLLLELYL ENERRSGGGP
210 220 230 240 250
LEGLRSLPGQ LGTVISFQQW QVAERVLKQK HWLQGIELSL VPHYDVLEPE
260 270 280 290 300
ALAEGVSGRD HSATQESGVI GHAPTGTGGL AGALTMAVGS GEAPQQLGTL
310 320 330 340 350
LRAGPVGAPG QALPVDSGSI RIQGSMGSTS PVDPVESSTE LPEQVGPMAS
360 370 380 390 400
DSVGVQEQEG LGEVATGQEG LMGLVGTAME SVETGLESPG YGEMQKQEGL
410 420 430 440 450
VEMVMSVEPG AVRYLQLYYE DLLASLEDVA LFPLEGTDVT GFRLCGARAP
460 470 480 490 500
CQAAQELLQS LLGSISCHTL NMKHPGSARF LLGVEGQHLL HRLEAQFQCV
510 520 530 540 550
FGTEHLASAT LDIDPERTDP TEALQVLHGH ITGIDQESLR LEDVRELLAT
560 570 580 590 600
LESPHGGEDR VPLEMEKEKP GGPGETVVEQ QEEIPTLEAE EEPVALSTGA
610 620 630 640 650
RGQLEEEATL QLAIHRSLES QSQVADQQEA NALRRAMALS LLEAEEALDE
660 670 680 690 700
DTGGEAQLVV HTSFEQDVDE LNQALSNALE AHLREETVSL QGRMLPPELG
710 720 730 740 750
ARLERCHDVS ATLRGDRVVL RGFGVQPARA ARHLAALLVD PWDQNLTFPL
760 770 780 790 800
EASKPNLSEQ GLKEPLGRLE ALEENSQEFQ DVVRAFYSTL DAVHGRIRIV
810 820 830 840 850
RVERVSHPLL QQQYQLHRER LMQSCQQRPV EQVLYHGTSE SAVLDICAHG
860 870 880 890 900
FNRSFCGRNG TLYGQGVYFA KRASLSVLDR YSPPNAEGYK AVFVAQVLTG
910 920 930 940 950
DYGQGSRGLK APPLRVSGQV LRYDSAVDCL QQPRIFVIFH DTQALPTHLI
960
TCKNILPGTP
Length:960
Mass (Da):103,679
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3106C499027AE9F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5H1ZRM9A0A5H1ZRM9_MOUSE
Poly [ADP-ribose] polymerase
Parp10
110Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH25608 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAC32856 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti255G → S in BAC25913 (PubMed:16141072).Curated1
Sequence conflicti287A → T in BAE38685 (PubMed:16141072).Curated1
Sequence conflicti315V → I in BAE38685 (PubMed:16141072).Curated1
Sequence conflicti491H → Y in BAE38685 (PubMed:16141072).Curated1
Sequence conflicti647A → S in BAE38685 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK028373 mRNA Translation: BAC25913.1
AK046755 mRNA Translation: BAC32856.1 Frameshift.
AK153205 mRNA Translation: BAE31805.1
AK166291 mRNA Translation: BAE38685.1
AC110211 Genomic DNA No translation available.
BC023056 mRNA Translation: AAH23056.1
BC024074 mRNA Translation: AAH24074.1
BC025608 mRNA Translation: AAH25608.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49650.1

NCBI Reference Sequences

More...
RefSeqi
NP_001157047.1, NM_001163575.1
NP_001157048.1, NM_001163576.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000075689; ENSMUSP00000075110; ENSMUSG00000063268
ENSMUST00000165738; ENSMUSP00000129765; ENSMUSG00000063268

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
671535

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:671535

UCSC genome browser

More...
UCSCi
uc007wjj.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK028373 mRNA Translation: BAC25913.1
AK046755 mRNA Translation: BAC32856.1 Frameshift.
AK153205 mRNA Translation: BAE31805.1
AK166291 mRNA Translation: BAE38685.1
AC110211 Genomic DNA No translation available.
BC023056 mRNA Translation: AAH23056.1
BC024074 mRNA Translation: AAH24074.1
BC025608 mRNA Translation: AAH25608.1 Different initiation.
CCDSiCCDS49650.1
RefSeqiNP_001157047.1, NM_001163575.1
NP_001157048.1, NM_001163576.1

3D structure databases

SMRiQ8CIE4
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129765

PTM databases

iPTMnetiQ8CIE4
PhosphoSitePlusiQ8CIE4

Proteomic databases

EPDiQ8CIE4
MaxQBiQ8CIE4
PaxDbiQ8CIE4
PRIDEiQ8CIE4
ProteomicsDBi334670
357507

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
28206, 108 antibodies

Genome annotation databases

EnsembliENSMUST00000075689; ENSMUSP00000075110; ENSMUSG00000063268
ENSMUST00000165738; ENSMUSP00000129765; ENSMUSG00000063268
GeneIDi671535
KEGGimmu:671535
UCSCiuc007wjj.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84875
MGIiMGI:3712326, Parp10
VEuPathDBiHostDB:ENSMUSG00000063268

Phylogenomic databases

eggNOGiENOG502R572, Eukaryota
GeneTreeiENSGT00940000162035
HOGENOMiCLU_014825_3_2_1
OMAiQAFYNTL
OrthoDBi681829at2759
PhylomeDBiQ8CIE4
TreeFamiTF328965

Enzyme and pathway databases

ReactomeiR-MMU-197264, Nicotinamide salvaging

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
671535, 2 hits in 62 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Parp10, mouse

Protein Ontology

More...
PROi
PR:Q8CIE4
RNActiQ8CIE4, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000063268, Expressed in adult mammalian kidney and 159 other tissues

Family and domain databases

CDDicd12547, RRM1_2_PAR10, 1 hit
Gene3Di3.30.70.330, 2 hits
InterProiView protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR034464, PAR10_RRM1_2
IPR012317, Poly(ADP-ribose)pol_cat_dom
PfamiView protein in Pfam
PF00644, PARP, 1 hit
PROSITEiView protein in PROSITE
PS51059, PARP_CATALYTIC, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPAR10_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CIE4
Secondary accession number(s): F6Z9X8
, Q3TLV7, Q3U6C0, Q8BSZ1, Q8C8L6, Q8R133, Q8R1U9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 16, 2019
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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