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Protein

Serpin A11

Gene

Serpina11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Names & Taxonomyi

Protein namesi
Recommended name:
Serpin A11
Gene namesi
Name:Serpina11
Synonyms:Gm895
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2685741 Serpina11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000004197422 – 424Serpin A11Add BLAST403

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi108N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi171N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi352N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi387N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ8CIE0
PaxDbiQ8CIE0
PRIDEiQ8CIE0

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074258

Structurei

3D structure databases

ProteinModelPortaliQ8CIE0
SMRiQ8CIE0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the serpin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000238521
HOVERGENiHBG005957
InParanoidiQ8CIE0
KOiK04525
PhylomeDBiQ8CIE0

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q8CIE0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPVWLWLWL LVAEVLLPVH CQPFSAHGDK SLGASQPASH QSLEPAPAYH
60 70 80 90 100
KVTPTITNFA LRLYKQLAEE VAGNILFSPV SLSSSLALLS LGAHADTQTQ
110 120 130 140 150
ILESLGFNLT ETPAADVHRG FQSLLHTLDL PSPKLELKLG HSLFLDRQLK
160 170 180 190 200
PQQRFLDSAK ELYGALAFSA NFTEAAATGQ QINDLVRKQT YGQVVGCLPE
210 220 230 240 250
FSHDTLMVLL NYIFFKAKWK HPFDRYQTRK QESFSLDQRT PLRIPMMRQK
260 270 280 290 300
EMHRFLYDQE ASCTVLQIEY SGTALLLLVL PDPGKMQQVE AALQPETLRR
310 320 330 340 350
WGQRFLPSLL DLHLPRFSIS ATYNLEEILP LIGLGNLFDM EADLSGIMGQ
360 370 380 390 400
LNKTVSRVSH KAIVDMNEKG TEAAAASGLL SQPPALNMTS APQAHYNRPF
410 420
LLLLWEVTTQ SLLFLGKVVN PAAG
Length:424
Mass (Da):47,188
Last modified:March 1, 2003 - v1
Checksum:iD176AAF8D5A06D34
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QLL8E9QLL8_MOUSE
Serpin A11
Serpina11
427Annotation score:
E9QK54E9QK54_MOUSE
Serpin A11
Serpina11
425Annotation score:
D3Z0P3D3Z0P3_MOUSE
Serpin A11
Serpina11
236Annotation score:
H3BJV3H3BJV3_MOUSE
Serpin A11
Serpina11
258Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC024087 mRNA Translation: AAH24087.1
BC096585 mRNA Translation: AAH96585.1
RefSeqiNP_955018.2, NM_199314.2
UniGeneiMm.201338

Genome annotation databases

GeneIDi380780
KEGGimmu:380780

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC024087 mRNA Translation: AAH24087.1
BC096585 mRNA Translation: AAH96585.1
RefSeqiNP_955018.2, NM_199314.2
UniGeneiMm.201338

3D structure databases

ProteinModelPortaliQ8CIE0
SMRiQ8CIE0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074258

Proteomic databases

MaxQBiQ8CIE0
PaxDbiQ8CIE0
PRIDEiQ8CIE0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi380780
KEGGimmu:380780

Organism-specific databases

CTDi256394
MGIiMGI:2685741 Serpina11

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000238521
HOVERGENiHBG005957
InParanoidiQ8CIE0
KOiK04525
PhylomeDBiQ8CIE0

Miscellaneous databases

PROiPR:Q8CIE0
SOURCEiSearch...

Family and domain databases

InterProiView protein in InterPro
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSPA11_MOUSE
AccessioniPrimary (citable) accession number: Q8CIE0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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