Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tetratricopeptide repeat protein 23

Gene

Ttc23

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Tetratricopeptide repeat protein 23
Short name:
TPR repeat protein 23
Gene namesi
Name:Ttc23
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1914259 Ttc23

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002895491 – 488Tetratricopeptide repeat protein 23Add BLAST488

Proteomic databases

PaxDbiQ8CHY7
PRIDEiQ8CHY7

PTM databases

iPTMnetiQ8CHY7
PhosphoSitePlusiQ8CHY7

Expressioni

Gene expression databases

BgeeiENSMUSG00000030555 Expressed in 189 organ(s), highest expression level in testis
CleanExiMM_TTC23
ExpressionAtlasiQ8CHY7 baseline and differential
GenevisibleiQ8CHY7 MM

Interactioni

Protein-protein interaction databases

BioGridi211872, 130 interactors
STRINGi10090.ENSMUSP00000032774

Structurei

3D structure databases

ProteinModelPortaliQ8CHY7
SMRiQ8CHY7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati45 – 78TPR 1Add BLAST34
Repeati137 – 170TPR 2Add BLAST34
Repeati186 – 219TPR 3Add BLAST34
Repeati228 – 261TPR 4Add BLAST34
Repeati398 – 431TPR 5Add BLAST34

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiENOG410IJRU Eukaryota
ENOG410XVCY LUCA
GeneTreeiENSGT00530000063847
HOGENOMiHOG000154704
HOVERGENiHBG096816
InParanoidiQ8CHY7
OMAiHWKLAEA
OrthoDBiEOG091G08RQ
PhylomeDBiQ8CHY7
TreeFamiTF332604

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 2 hits

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CHY7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQESQDTHMS SHLDEVVAAV SVTSKNRIPN KLLQTALFQP PREKLHLCEE
60 70 80 90 100
RAKSYSSSRE YKQAIQELVR CVALTRICYG DWHWKLAEAY VNLAQGYLQL
110 120 130 140 150
KGLSLQAKQH AEKAKEILAN SIESPCHNKT DIFKCSLELF YTLGRALLSL
160 170 180 190 200
QKFKDASENL IKAERLSKEM LQCGNIVKEE WIEIQSRIKL SFAQLYQGQK
210 220 230 240 250
RSKEAFPFYQ KALEYTEITK DEKSLECVQV LRELAGVEQA LGLYAAAISH
260 270 280 290 300
FSRDRLPTPQ PCPLGHKCCC PSPFLSPVLN VTWRPFYSSQ VDEEEAHLII
310 320 330 340 350
LSKDPSPEEA ADSAHFIARA AAASGMHDHR DVAEKYFQES MTSIKDSEGA
360 370 380 390 400
ERAKFLSIQD EFCSFLQTTG QKERAAMILR ESLEAKVGAF GDFSPEVAET
410 420 430 440 450
YRALGRADLA QGNNSGAYAK LKKCVQIETF LYGSQDKKTL ATQHTIDTLS
460 470 480
KISEAAGKSR QSVKAKVAFC TSAPQYGMPG KGRHSVAD
Length:488
Mass (Da):54,608
Last modified:March 1, 2003 - v1
Checksum:i1FB806B8408651CF
GO
Isoform 2 (identifier: Q8CHY7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-169: Missing.
     254-295: Missing.

Show »
Length:277
Mass (Da):30,562
Checksum:iD71E5043647E3F9E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9QKU9E9QKU9_MOUSE
Tetratricopeptide repeat protein 23
Ttc23
446Annotation score:
A0A140LHI7A0A140LHI7_MOUSE
Tetratricopeptide repeat protein 23
Ttc23
252Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0260191 – 169Missing in isoform 2. 1 PublicationAdd BLAST169
Alternative sequenceiVSP_026020254 – 295Missing in isoform 2. 1 PublicationAdd BLAST42

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005431 mRNA Translation: BAB24025.1
BC038179 mRNA Translation: AAH38179.1
CCDSiCCDS21352.1 [Q8CHY7-1]
RefSeqiNP_001161947.1, NM_001168475.1
NP_001161948.1, NM_001168476.1 [Q8CHY7-2]
NP_080181.2, NM_025905.3 [Q8CHY7-1]
UniGeneiMm.249356

Genome annotation databases

EnsembliENSMUST00000032774; ENSMUSP00000032774; ENSMUSG00000030555 [Q8CHY7-1]
GeneIDi67009
KEGGimmu:67009
UCSCiuc009his.2 mouse [Q8CHY7-1]
uc009hiu.2 mouse [Q8CHY7-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005431 mRNA Translation: BAB24025.1
BC038179 mRNA Translation: AAH38179.1
CCDSiCCDS21352.1 [Q8CHY7-1]
RefSeqiNP_001161947.1, NM_001168475.1
NP_001161948.1, NM_001168476.1 [Q8CHY7-2]
NP_080181.2, NM_025905.3 [Q8CHY7-1]
UniGeneiMm.249356

3D structure databases

ProteinModelPortaliQ8CHY7
SMRiQ8CHY7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211872, 130 interactors
STRINGi10090.ENSMUSP00000032774

PTM databases

iPTMnetiQ8CHY7
PhosphoSitePlusiQ8CHY7

Proteomic databases

PaxDbiQ8CHY7
PRIDEiQ8CHY7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032774; ENSMUSP00000032774; ENSMUSG00000030555 [Q8CHY7-1]
GeneIDi67009
KEGGimmu:67009
UCSCiuc009his.2 mouse [Q8CHY7-1]
uc009hiu.2 mouse [Q8CHY7-2]

Organism-specific databases

CTDi64927
MGIiMGI:1914259 Ttc23

Phylogenomic databases

eggNOGiENOG410IJRU Eukaryota
ENOG410XVCY LUCA
GeneTreeiENSGT00530000063847
HOGENOMiHOG000154704
HOVERGENiHBG096816
InParanoidiQ8CHY7
OMAiHWKLAEA
OrthoDBiEOG091G08RQ
PhylomeDBiQ8CHY7
TreeFamiTF332604

Miscellaneous databases

PROiPR:Q8CHY7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030555 Expressed in 189 organ(s), highest expression level in testis
CleanExiMM_TTC23
ExpressionAtlasiQ8CHY7 baseline and differential
GenevisibleiQ8CHY7 MM

Family and domain databases

Gene3Di1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiTTC23_MOUSE
AccessioniPrimary (citable) accession number: Q8CHY7
Secondary accession number(s): Q9DAY3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again