UniProtKB - Q8CHU3 (EPN2_MOUSE)

BLAST

>sp|Q8CHU3|EPN2_MOUSE Epsin-2 OS=Mus musculus OX=10090 GN=Epn2 PE=1 SV=1
MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMV
WKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG
INVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSTS
YSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQSSES
VQTARGSKEERLRRGDDLRLQMALEESRRDTVKVPKKKEAKACCKPGSHSQQTTLLDLMD
ALPSSGPVTQKTEPWSAGASANQTNPWGGTVAPSNITDPWPSFGTKPAASVDPWGVPTTA
STQSVPKNSDPWAASQQPASNAGKTTDAWGAAKPSSASGSFELFSNFNGTVKDDFSEFDN
LRTSKKPAESGASVPPQDSRTTSPDLFESQSLTSASSKPSSARKTPESFLGPNAALVNLD
SLVTKPAPPAQSLNPFLAPGAAAPAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPG
VETVAPMTSVAPHSSVGASGSSLTPLGPTAMNMVGSVGIPPSAAQSTGTTNPFLL

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History
Entry version 145 (07 Nov 2018)
Sequence version 1 (01 Mar 2003)
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Protein

Epsin-2

Gene

Epn2

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Plays a role in the formation of clathrin-coated invaginations and endocytosis.By similarity

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	8	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	11	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	25	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	30	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	63	Phosphatidylinositol lipid headgroupBy similarity	1
Binding siteⁱ	73	Phosphatidylinositol lipid headgroupBy similarity	1

GO - Molecular functionⁱ

lipid binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

embryonic organ development
Source: MGI
Inferred from genetic interactionⁱ
- 19666558
endocytosis Source: UniProtKB-KW
in utero embryonic development
Source: MGI
Inferred from genetic interactionⁱ
- 19666558
negative regulation of sprouting angiogenesis Source: MGI
negative regulation of vascular endothelial growth factor receptor signaling pathway Source: MGI
Notch signaling pathway
Source: MGI
Inferred from genetic interactionⁱ
- 19666558
positive regulation of Notch signaling pathway Source: MGI
regulation of endocytosis Source: MGI

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Endocytosis
Ligand	Lipid-binding

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828 Clathrin-mediated endocytosis

Reactomeⁱ

R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828 Clathrin-mediated endocytosis

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Epsin-2 Alternative name(s): EPS-15-interacting protein 2 Intersectin-EH-binding protein 2 Short name: Ibp2
Gene namesⁱ	Name:Epn2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:1333766 Epn2

Keywords - Cellular componentⁱ

Cytoplasm

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000074517	1 – 595	Epsin-2Add BLAST		595

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	170	Omega-N-methylarginineCombined sources	1
Modified residueⁱ	173	PhosphoserineCombined sources	1
Modified residueⁱ	192	PhosphoserineCombined sources	1
Modified residueⁱ	195	PhosphoserineBy similarity	1
Modified residueⁱ	443	PhosphoserineBy similarity	1
Modified residueⁱ	465	PhosphothreonineBy similarity	1
Modified residueⁱ	526	PhosphoserineBy similarity	1

Post-translational modificationⁱ

Ubiquitinated.By similarity

Keywords - PTMⁱ

Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q8CHU3
PRIDEⁱ	Q8CHU3

PTM databases

iPTMnetⁱ	Q8CHU3
PhosphoSitePlusⁱ	Q8CHU3

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000001036 Expressed in 286 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_EPN2
ExpressionAtlasⁱ	Q8CHU3 baseline and differential
Genevisibleⁱ	Q8CHU3 MM

Interactionⁱ

Subunit structureⁱ

Binds EPS15, AP-2 and clathrin (By similarity). Interacts with UBQLN2 (By similarity). Interacts with ITSN1.By similarity1 Publication

Protein-protein interaction databases

BioGridⁱ	199486, 5 interactors
ELMⁱ	Q8CHU3
IntActⁱ	Q8CHU3, 3 interactors
Molecular INTeraction database More...MINTⁱ	Q8CHU3

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q8CHU3
SMRⁱ	Q8CHU3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	12 – 144	ENTHPROSITE-ProRule annotationAdd BLAST	133
Domainⁱ	218 – 237	UIM 1PROSITE-ProRule annotationAdd BLAST	20
Domainⁱ	255 – 274	UIM 2PROSITE-ProRule annotationAdd BLAST	20
Repeatⁱ	313 – 315	1	3
Repeatⁱ	325 – 327	2	3
Repeatⁱ	338 – 340	3	3
Repeatⁱ	352 – 354	4	3
Repeatⁱ	370 – 372	5	3
Repeatⁱ	387 – 389	6	3
Repeatⁱ	494 – 496	1	3
Repeatⁱ	508 – 510	2	3
Repeatⁱ	591 – 593	3	3

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	313 – 389	6 X 3 AA repeats of [DE]-P-WAdd BLAST		77
Regionⁱ	494 – 593	3 X 3 AA repeats of N-P-FAdd BLAST		100

Domainⁱ

The NPF repeat domain is involved in EPS15 binding.

The DPW repeat domain is involved in AP-2 and clathrin binding.

Sequence similaritiesⁱ

Belongs to the epsin family.Curated

Keywords - Domainⁱ

Repeat

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074611
HOGENOMⁱ	HOG000008298
HOVERGENⁱ	HBG006690
InParanoidⁱ	Q8CHU3
KEGG Orthology (KO) More...KOⁱ	K12471
OMAⁱ	EQEYGKS
PhylomeDBⁱ	Q8CHU3
TreeFamⁱ	TF313361

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03571 ENTH_epsin, 1 hit
Gene3Dⁱ	1.25.40.90, 1 hit
InterProⁱ	View protein in InterPro IPR013809 ENTH IPR008942 ENTH_VHS IPR027319 Epsin-2_metazoa IPR039416 Epsin_ENTH IPR003903 UIM_dom
PANTHERⁱ	PTHR12276:SF50 PTHR12276:SF50, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01417 ENTH, 1 hit
SMARTⁱ	View protein in SMART SM00273 ENTH, 1 hit SM00726 UIM, 2 hits
SUPFAMⁱ	SSF48464 SSF48464, 1 hit
PROSITEⁱ	View protein in PROSITE PS50942 ENTH, 1 hit PS50330 UIM, 2 hits

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 7 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q8CHU3-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV 
        60         70         80         90        100
VAFSEIMSMV WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI 
       110        120        130        140        150
FAIQTLKDFQ YIDRDGKDQG INVREKSKQL VALLKDEERL KVERVQALKT 
       160        170        180        190        200
KERMAQVATG VGSNQITFGR GSSQPNLSTS YSEQEYGKAG GSPASYHGST 
       210        220        230        240        250
SPRVSSELEQ ARPQTSGEEE LQLQLALAMS REVAEQSSES VQTARGSKEE 
       260        270        280        290        300
RLRRGDDLRL QMALEESRRD TVKVPKKKEA KACCKPGSHS QQTTLLDLMD 
       310        320        330        340        350
ALPSSGPVTQ KTEPWSAGAS ANQTNPWGGT VAPSNITDPW PSFGTKPAAS 
       360        370        380        390        400
VDPWGVPTTA STQSVPKNSD PWAASQQPAS NAGKTTDAWG AAKPSSASGS 
       410        420        430        440        450
FELFSNFNGT VKDDFSEFDN LRTSKKPAES GASVPPQDSR TTSPDLFESQ 
       460        470        480        490        500
SLTSASSKPS SARKTPESFL GPNAALVNLD SLVTKPAPPA QSLNPFLAPG 
       510        520        530        540        550
AAAPAPVNPF QVNQPQPLTL NQLRGSPVLG SSASFGSGPG VETVAPMTSV 
       560        570        580        590 
APHSSVGASG SSLTPLGPTA MNMVGSVGIP PSAAQSTGTT NPFLL

Length:595

Mass (Da):63,472

Last modified:March 1, 2003 - v1

Checksum:ⁱ255DC7BC7E1B2D13

Isoform 2 (identifier: Q8CHU3-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
237-248: Missing.

« Hide

        10         20         30         40         50
MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV 
        60         70         80         90        100
VAFSEIMSMV WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI 
       110        120        130        140        150
FAIQTLKDFQ YIDRDGKDQG INVREKSKQL VALLKDEERL KVERVQALKT 
       160        170        180        190        200
KERMAQVATG VGSNQITFGR GSSQPNLSTS YSEQEYGKAG GSPASYHGST 
       210        220        230        240        250
SPRVSSELEQ ARPQTSGEEE LQLQLALAMS REVAEQEERL RRGDDLRLQM 
       260        270        280        290        300
ALEESRRDTV KVPKKKEAKA CCKPGSHSQQ TTLLDLMDAL PSSGPVTQKT 
       310        320        330        340        350
EPWSAGASAN QTNPWGGTVA PSNITDPWPS FGTKPAASVD PWGVPTTAST 
       360        370        380        390        400
QSVPKNSDPW AASQQPASNA GKTTDAWGAA KPSSASGSFE LFSNFNGTVK 
       410        420        430        440        450
DDFSEFDNLR TSKKPAESGA SVPPQDSRTT SPDLFESQSL TSASSKPSSA 
       460        470        480        490        500
RKTPESFLGP NAALVNLDSL VTKPAPPAQS LNPFLAPGAA APAPVNPFQV 
       510        520        530        540        550
NQPQPLTLNQ LRGSPVLGSS ASFGSGPGVE TVAPMTSVAP HSSVGASGSS 
       560        570        580 
LTPLGPTAMN MVGSVGIPPS AAQSTGTTNP FLL

Note: No experimental confirmation available.

Show »

Length:583

Mass (Da):62,253

Checksum:ⁱEFC06A1371A85980

Computationally mapped potential isoform sequencesⁱ

There are 7 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

J3QNT7	J3QNT7_MOUSE	Epsin-2 Epsin-2	Epn2	640	Annotation score:
Q5NCM5	Q5NCM5_MOUSE	Epsin-2 Epsin-2	Epn2	634	Annotation score:
Q5NCM6	Q5NCM6_MOUSE	Epsin-2 Epsin-2	Epn2	577	Annotation score:
F7CUV7	F7CUV7_MOUSE	Epsin-2 Epsin-2	Epn2	274	Annotation score:
F7CD65	F7CD65_MOUSE	Epsin-2 Epsin-2	Epn2	148	Annotation score:
A8Y5D4	A8Y5D4_MOUSE	Epsin-2 Epsin-2	Epn2	79	Annotation score:
A8Y5D5	A8Y5D5_MOUSE	Epsin-2 Epsin-2	Epn2	17	Annotation score:

Sequence cautionⁱ

The sequence AAC97476 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	75	Y → S in AAC97476 (PubMed:9813051).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_009157	237 – 248	Missing in isoform 2. 2 PublicationsAdd BLAST		12

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK036331 mRNA Translation: BAC29387.1 AL604029 Genomic DNA No translation available. BC039138 mRNA Translation: AAH39138.1 AF057286 mRNA Translation: AAC97476.1 Different initiation.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS24816.1 [Q8CHU3-1] CCDS56779.1 [Q8CHU3-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001239118.1, NM_001252189.1 [Q8CHU3-2] NP_034278.1, NM_010148.3 [Q8CHU3-1] XP_017169742.1, XM_017314253.1
UniGeneⁱ	Mm.139695 Mm.489800

Genome annotation databases

Ensemblⁱ	ENSMUST00000001063; ENSMUSP00000001063; ENSMUSG00000001036 [Q8CHU3-1] ENSMUST00000108713; ENSMUSP00000104353; ENSMUSG00000001036 [Q8CHU3-2] ENSMUST00000178202; ENSMUSP00000136553; ENSMUSG00000001036 [Q8CHU3-1]
GeneIDⁱ	13855
KEGGⁱ	mmu:13855
UCSC genome browser More...UCSCⁱ	uc007jhv.2 mouse [Q8CHU3-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q8CHU3	Epsin-2		RAT		583	UniRef90_Q8CHU3
Uncharacterized protein		MOUSE		583
UPI0007DA5181		CRIGR		605
UPI00077DE770		PERMB		596
UPI00038BBAB6		MICOH		595
+23

Protein	Similar proteins		Species	Score	Length	Source
Q8CHU3	Epsin-2		HUMAN		641	UniRef50_O95208
Epsin-2		RAT		583
Uncharacterized protein		ICTTR		648
Uncharacterized protein		NOMLE		643
Uncharacterized protein		MACNE		643
+574

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK036331 mRNA Translation: BAC29387.1 AL604029 Genomic DNA No translation available. BC039138 mRNA Translation: AAH39138.1 AF057286 mRNA Translation: AAC97476.1 Different initiation.
CCDSⁱ	CCDS24816.1 [Q8CHU3-1] CCDS56779.1 [Q8CHU3-2]
RefSeqⁱ	NP_001239118.1, NM_001252189.1 [Q8CHU3-2] NP_034278.1, NM_010148.3 [Q8CHU3-1] XP_017169742.1, XM_017314253.1
UniGeneⁱ	Mm.139695 Mm.489800

3D structure databases

ProteinModelPortalⁱ	Q8CHU3
SMRⁱ	Q8CHU3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	199486, 5 interactors
ELMⁱ	Q8CHU3
IntActⁱ	Q8CHU3, 3 interactors
MINTⁱ	Q8CHU3

PTM databases

iPTMnetⁱ	Q8CHU3
PhosphoSitePlusⁱ	Q8CHU3

Proteomic databases

PeptideAtlasⁱ	Q8CHU3
PRIDEⁱ	Q8CHU3

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000001063; ENSMUSP00000001063; ENSMUSG00000001036 [Q8CHU3-1] ENSMUST00000108713; ENSMUSP00000104353; ENSMUSG00000001036 [Q8CHU3-2] ENSMUST00000178202; ENSMUSP00000136553; ENSMUSG00000001036 [Q8CHU3-1]
GeneIDⁱ	13855
KEGGⁱ	mmu:13855
UCSCⁱ	uc007jhv.2 mouse [Q8CHU3-1]

Organism-specific databases

CTDⁱ	22905
MGIⁱ	MGI:1333766 Epn2

Phylogenomic databases

GeneTreeⁱ	ENSGT00550000074611
HOGENOMⁱ	HOG000008298
HOVERGENⁱ	HBG006690
InParanoidⁱ	Q8CHU3
KOⁱ	K12471
OMAⁱ	EQEYGKS
PhylomeDBⁱ	Q8CHU3
TreeFamⁱ	TF313361

Enzyme and pathway databases

Reactomeⁱ	R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis R-MMU-8856828 Clathrin-mediated endocytosis

Reactomeⁱ

R-MMU-8856825 Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828 Clathrin-mediated endocytosis

Miscellaneous databases

ChiTaRSⁱ	Epn2 mouse
Protein Ontology More...PROⁱ	PR:Q8CHU3
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000001036 Expressed in 286 organ(s), highest expression level in secondary oocyte
CleanExⁱ	MM_EPN2
ExpressionAtlasⁱ	Q8CHU3 baseline and differential
Genevisibleⁱ	Q8CHU3 MM

Family and domain databases

CDDⁱ	cd03571 ENTH_epsin, 1 hit
Gene3Dⁱ	1.25.40.90, 1 hit
InterProⁱ	View protein in InterPro IPR013809 ENTH IPR008942 ENTH_VHS IPR027319 Epsin-2_metazoa IPR039416 Epsin_ENTH IPR003903 UIM_dom
PANTHERⁱ	PTHR12276:SF50 PTHR12276:SF50, 1 hit
Pfamⁱ	View protein in Pfam PF01417 ENTH, 1 hit
SMARTⁱ	View protein in SMART SM00273 ENTH, 1 hit SM00726 UIM, 2 hits
SUPFAMⁱ	SSF48464 SSF48464, 1 hit
PROSITEⁱ	View protein in PROSITE PS50942 ENTH, 1 hit PS50330 UIM, 2 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EPN2_MOUSE
Accessionⁱ	Q8CHU3Primary (citable) accession number: Q8CHU3 Secondary accession number(s): O70447, Q5NCM4, Q8BZ85
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
	Last sequence update:	March 1, 2003
	Last modified:	November 7, 2018
	This is version 145 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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Supporting data

UniProtKB - Q8CHU3 (EPN2_MOUSE)

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Epsin-2

Epn2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Other locations

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ