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Protein
Submitted name:

Apoptosis-associated speck-like protein

Gene

Pycard

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ion channel binding Source: RGD
  • protease binding Source: RGD
  • protein homodimerization activity Source: HGNC
  • Pyrin domain binding Source: HGNC

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptosis-associated speck-like proteinImported
Gene namesi
Name:PycardImported
Synonyms:rASCImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi628637 Pycard

Subcellular locationi

PTM / Processingi

PTM databases

iPTMnetiQ8CHK8
PhosphoSitePlusiQ8CHK8

Expressioni

Gene expression databases

GenevisibleiQ8CHK8 RN

Interactioni

GO - Molecular functioni

  • ion channel binding Source: RGD
  • protease binding Source: RGD
  • protein homodimerization activity Source: HGNC
  • Pyrin domain binding Source: HGNC

Structurei

3D structure databases

ProteinModelPortaliQ8CHK8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 91PyrinInterPro annotationAdd BLAST91
Domaini105 – 193CARDInterPro annotationAdd BLAST89

Phylogenomic databases

eggNOGiENOG410J02A Eukaryota
ENOG4111XEQ LUCA
HOGENOMiHOG000034090
HOVERGENiHBG018739
KOiK12799
PhylomeDBiQ8CHK8

Family and domain databases

CDDicd08330 CARD_ASC_NALP1, 1 hit
InterProiView protein in InterPro
IPR001315 CARD
IPR033516 CARD8/ASC/NALP1_CARD
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF00619 CARD, 1 hit
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 2 hits
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit
PS50824 DAPIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CHK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRARDAILD ALENLTADEF KKFKMKLLTA PVREGYGRIP RGALLQMDPI
60 70 80 90 100
DLTDKLVSYY LEGYGLELTM SVLRDMGIQE LAEQLQKIME ESGAVATATS
110 120 130 140 150
VPAQGTARTE HFVDQHRQAL IARVTKVDGL LDALYGNVLT EGQYQAVRAE
160 170 180 190
TPNQNKMRKL FSFAPAWNLT CKNLFLEALR QTQPYLVTDL EQS
Length:193
Mass (Da):21,654
Last modified:March 1, 2003 - v1
Checksum:iF3B27B560D86A17B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB053165 mRNA Translation: BAC43754.1
RefSeqiNP_758825.1, NM_172322.1
UniGeneiRn.7817

Genome annotation databases

GeneIDi282817
KEGGirno:282817
UCSCiRGD:628637 rat

Similar proteinsi

Entry informationi

Entry nameiQ8CHK8_RAT
AccessioniPrimary (citable) accession number: Q8CHK8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: June 20, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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