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Entry version 128 (02 Jun 2021)
Sequence version 2 (03 Jul 2003)
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Protein

GRIP and coiled-coil domain-containing protein 2

Gene

Gcc2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2 (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6811440, Retrograde transport at the Trans-Golgi-Network

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
GRIP and coiled-coil domain-containing protein 2
Alternative name(s):
185 kDa Golgi coiled-coil protein
Short name:
GCC185
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Gcc2
Synonyms:Kiaa0336
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1917547, Gcc2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001900751 – 1679GRIP and coiled-coil domain-containing protein 2Add BLAST1679

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei1474PhosphoserineBy similarity1
Modified residuei1478PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8CHG3

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8CHG3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8CHG3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CHG3

PRoteomics IDEntifications database

More...
PRIDEi
Q8CHG3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
267778

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CHG3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CHG3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Interacts (via GRIP domain) with RAB6A (preferentially in its GTP-bound form). May interact (RAB6A-dependent) with ARL1; might be involved in GCC2 Golgi localization.

Interacts (probably via GRIP domain) with RAB9A (preferentially in its GTP-bound form).

Interacts with CLASP1 and CLASP2; recruits both proteins to membranes of the TGN.

Interacts with STX16 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q8CHG3, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000054033

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CHG3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CHG3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1604 – 1654GRIPPROSITE-ProRule annotationAdd BLAST51

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 23DisorderedSequence analysisAdd BLAST23
Regioni1467 – 1521DisorderedSequence analysisAdd BLAST55
Regioni1569 – 1679Mediates interaction with RAB9ABy similarityAdd BLAST111
Regioni1569 – 1608Mediates interaction with RAB6ABy similarityAdd BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili31 – 1613Sequence analysisAdd BLAST1583

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1467 – 1481Polar residuesSequence analysisAdd BLAST15
Compositional biasi1482 – 1510Basic and acidic residuesSequence analysisAdd BLAST29

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Extended rod-like protein with coiled-coil domains.

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0864, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CHG3

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032023, GCC2_Rab_bind
IPR000237, GRIP_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01465, GRIP, 1 hit
PF16704, Rab_bind, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00755, Grip, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50913, GRIP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q8CHG3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDSAPDAVA AAPSGTPKSK LETLPREDLI KFAKKQMMLL QKAKARCTEL
60 70 80 90 100
DKEVEELKSK PVDGGTDDII KVLTERLDAL LLEKAETEQQ CLCLKKENVK
110 120 130 140 150
MKQEVEDSVT KLEETHKEFE QSHRNYVKEI ESCKNELMAV HSEHSKETAI
160 170 180 190 200
LQKELEEAVH KQVELREQLK SQSDSEDNVR KLQEEIQNIT AAFEEQISCL
210 220 230 240 250
EKKLEATSDE KQQEIIHLQK VIEDKAQHYQ KDINTFQAEI LQLRATHKEE
260 270 280 290 300
VTELMSQIET SAKEHEAEIN KLKENRVTQC EASENIPEKY QCESENLNEV
310 320 330 340 350
ASDASPESQN CSVALQEDPS AEQTVCDKVR QLEDSLKELE SQHSILKDEV
360 370 380 390 400
TYMNNLKLKL EMDAQHIKDE FFHEREDLEF KINELLLAKE EQGYVVEKLK
410 420 430 440 450
YEREDLNRQL CCAVEQHNKE IQRLQEHHQK EVSELSETFI SGSEKEKLAL
460 470 480 490 500
MFEIQGLKEQ CENLQHEKQE VVLNYESLRE MMEILQTELG ESAGKISQEF
510 520 530 540 550
ETMKQQQASD VHELQQKLRS AFNEKDALLE TVNRLQGENE KLLSQQELVP
560 570 580 590 600
ELESTIKNLQ ADNSMYLASL GQKDTMLQEL EAKISSLAKE KDDFISKIKT
610 620 630 640 650
SHEEMDDLHQ KWEREQRLSV ELREAAGQAA QHNSELRQRV SELTGKLDEL
660 670 680 690 700
VREKSQNDQS ITVQMKTMTE DQEALSSKIK SLYEENNRLH SEKAQLSRDL
710 720 730 740 750
EALQAQQDFA HKEHVAEFEK KLQLMVEERD DLNKLLENEQ VQKSFVKTQL
760 770 780 790 800
YEYLKQLRAS ILEENEEEDV VKLIQAVGES LVKVKEEEHN LVFEYDARVL
810 820 830 840 850
ELENKIKCLQ EDSAVQCEEL RTLVRDSEQE KILLRKELDA VTSAKEALQL
860 870 880 890 900
DLLEMKNTNE KASLENQTLS TQVEELSQTL HSRNEVHDEK VLVIEHENLR
910 920 930 940 950
LLLKQRESEL QDVRAELILL KDSLEKSPSV KDQLSLVKEL EEKIESLEKE
960 970 980 990 1000
SKDKDEKISK IKLVAVKAKK ELDSNRKEAQ TLREELESVR SEKDRLSASM
1010 1020 1030 1040 1050
KEFLQGAESY KSLLLEYDKQ SEQLDVEKER AHNFERHIED LTKQLRNSTC
1060 1070 1080 1090 1100
QYERLTSDNE DLLARIETLQ ANAKLLEAQI LEVQKAKGVV EKELDAEELQ
1110 1120 1130 1140 1150
KEQKIKEHVS TVNELEELQL QFQKEKKQLQ KTMQELELVK KDAQQTTLMN
1160 1170 1180 1190 1200
MEIADYERLM KELNQKLTNK NSTIEDLEQE MKIQKEKQET LQEEITSLQS
1210 1220 1230 1240 1250
SVQHYEEKNT KIKQLLVKTK KELADAKQAE TDHLLLQASL KGELEASQQQ
1260 1270 1280 1290 1300
VEVYKIQLAE MTSEKHKIHE HLKTSAEQHQ RTLSAYQQRV VALQEESRAA
1310 1320 1330 1340 1350
KAEQAAVTSE FESYKVRVHN VLKQQKNKSV SQVETEGAKQ EREHLEMLID
1360 1370 1380 1390 1400
QLKIKLQDSQ NSLQISVSEY QTLQAEHDTL LERHNRMLQE TVTKEAELRE
1410 1420 1430 1440 1450
KLCSVQSENT MMKSEHSQTM CQLTSQNEAL RTSFRDQVRH LQDEHRKTVE
1460 1470 1480 1490 1500
TLQHQLSKLE AQLFQLKSEP STRSPASSHQ PSKSLRERRT TDLPLLDMHT
1510 1520 1530 1540 1550
VAREEGEGME TTDSESVSSA GTHIQSLEQL LSSPDTKLER LAETSLWHNE
1560 1570 1580 1590 1600
FTKEELAEKL SSTTKSADHL NGLLRETEAT NAILMEQIKL LKSEIRRLER
1610 1620 1630 1640 1650
NQEREKSVAN LEYLKNVLLR FIFLKPGSER ERLLPVIDTM LQLSPEEKGK
1660 1670
LATVAQGEEE SASRSSGWAS YLHSWSGLR
Length:1,679
Mass (Da):194,445
Last modified:July 3, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E2F84263E5E0103
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B2RSU7B2RSU7_MOUSE
GRIP and coiled-coil domain contain...
Gcc2
1,680Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYI9E0CYI9_MOUSE
GRIP and coiled-coil domain-contain...
Gcc2
1,576Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PWI6E9PWI6_MOUSE
GRIP and coiled-coil domain-contain...
Gcc2
1,644Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CX24E0CX24_MOUSE
GRIP and coiled-coil domain-contain...
Gcc2
51Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CY89E0CY89_MOUSE
GRIP and coiled-coil domain-contain...
Gcc2
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6UT01F6UT01_MOUSE
GRIP and coiled-coil domain-contain...
Gcc2
181Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH27339 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti440I → M in AAH27339 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC027339 mRNA Translation: AAH27339.1 Different initiation.
AK011206 mRNA Translation: BAB27466.3
AK045701 mRNA Translation: BAC32463.2
AB093232 Transcribed RNA Translation: BAC41416.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC027339 mRNA Translation: AAH27339.1 Different initiation.
AK011206 mRNA Translation: BAB27466.3
AK045701 mRNA Translation: BAC32463.2
AB093232 Transcribed RNA Translation: BAC41416.1

3D structure databases

SMRiQ8CHG3
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ8CHG3, 2 interactors
STRINGi10090.ENSMUSP00000054033

PTM databases

iPTMnetiQ8CHG3
PhosphoSitePlusiQ8CHG3

Proteomic databases

EPDiQ8CHG3
jPOSTiQ8CHG3
MaxQBiQ8CHG3
PaxDbiQ8CHG3
PRIDEiQ8CHG3
ProteomicsDBi267778

Organism-specific databases

MGIiMGI:1917547, Gcc2

Rodent Unidentified Gene-Encoded large proteins database

More...
Rougei
Search...

Phylogenomic databases

eggNOGiKOG0864, Eukaryota
InParanoidiQ8CHG3

Enzyme and pathway databases

ReactomeiR-MMU-6811440, Retrograde transport at the Trans-Golgi-Network

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Gcc2, mouse

Protein Ontology

More...
PROi
PR:Q8CHG3
RNActiQ8CHG3, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

InterProiView protein in InterPro
IPR032023, GCC2_Rab_bind
IPR000237, GRIP_dom
PfamiView protein in Pfam
PF01465, GRIP, 1 hit
PF16704, Rab_bind, 1 hit
SMARTiView protein in SMART
SM00755, Grip, 1 hit
PROSITEiView protein in PROSITE
PS50913, GRIP, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGCC2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CHG3
Secondary accession number(s): Q8BR44, Q8R2Q5, Q9CT45
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 3, 2003
Last sequence update: July 3, 2003
Last modified: June 2, 2021
This is version 128 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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