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Entry version 141 (12 Aug 2020)
Sequence version 1 (01 Mar 2003)
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Protein

SAFB-like transcription modulator

Gene

Sltm

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor, RNA-binding
Biological processApoptosis, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SAFB-like transcription modulator
Alternative name(s):
Modulator of estrogen-induced transcription
SAF-like transcription modulator
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Sltm
Synonyms:Met
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1913910, Sltm

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003077992 – 1031SAFB-like transcription modulatorAdd BLAST1030

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei93PhosphoserineBy similarity1
Modified residuei97PhosphoserineBy similarity1
Modified residuei139PhosphoserineCombined sources1
Modified residuei144PhosphoserineBy similarity1
Modified residuei289PhosphoserineCombined sources1
Modified residuei401N6-acetyllysineBy similarity1
Modified residuei421PhosphoserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki500Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei549PhosphoserineCombined sources1
Modified residuei550PhosphoserineCombined sources1
Modified residuei552PhosphoserineCombined sources1
Modified residuei747PhosphoserineBy similarity1
Modified residuei786PhosphoserineBy similarity1
Modified residuei797PhosphoserineBy similarity1
Modified residuei812PhosphoserineBy similarity1
Cross-linki881Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei906PhosphoserineBy similarity1
Modified residuei920PhosphoserineBy similarity1
Modified residuei995PhosphoserineBy similarity1
Modified residuei999PhosphoserineCombined sources1
Modified residuei1011PhosphoserineBy similarity1
Modified residuei1014Omega-N-methylarginineCombined sources1
Modified residuei1016PhosphoserineBy similarity1
Modified residuei1018PhosphoserineBy similarity1
Modified residuei1021N6-acetyllysine; alternateBy similarity1
Cross-linki1021Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linki1024Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8CH25

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CH25

PeptideAtlas

More...
PeptideAtlasi
Q8CH25

PRoteomics IDEntifications database

More...
PRIDEi
Q8CH25

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CH25

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CH25

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000032212, Expressed in forelimb bud and 307 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8CH25, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8CH25, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
211628, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q8CH25, 3 interactors

Molecular INTeraction database

More...
MINTi
Q8CH25

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000049112

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CH25, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CH25

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini22 – 56SAPPROSITE-ProRule annotationAdd BLAST35
Domaini384 – 462RRMPROSITE-ProRule annotationAdd BLAST79

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili107 – 182Sequence analysisAdd BLAST76
Coiled coili608 – 727Sequence analysisAdd BLAST120

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi108 – 239Glu-richAdd BLAST132
Compositional biasi568 – 903Arg/Glu-richAdd BLAST336

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4661, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156573

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011145_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CH25

Identification of Orthologs from Complete Genome Data

More...
OMAi
FRRGRYF

Database of Orthologous Groups

More...
OrthoDBi
803886at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CH25

TreeFam database of animal gene trees

More...
TreeFami
TF325240

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.720.30, 1 hit
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
IPR003034, SAP_dom
IPR036361, SAP_dom_sf
IPR034780, SLTM

The PANTHER Classification System

More...
PANTHERi
PTHR15683:SF5, PTHR15683:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076, RRM_1, 1 hit
PF02037, SAP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 1 hit
SM00513, SAP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 1 hit
SSF68906, SSF68906, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102, RRM, 1 hit
PS50800, SAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CH25-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAAAGAVVA SAASGPAEGK KITELRVIDL RSELKRRNLD INGVKTVLVS
60 70 80 90 100
RLKQAIEEEG GDPDNIELTV STDTPNKKPT KGKGKKQEAD ELSGDASVED
110 120 130 140 150
DSFVKDCELE NQETHDQDGN EELKDLEEFG ENEEEIVHSQ ELLSTEENKT
160 170 180 190 200
TQEFVEAEAI EDREKEDIES QETEAQEGED DTFLTAQDGE EEENEKDIAG
210 220 230 240 250
SGDGTQEVSK PLPSEGSLAE ADHTAHEEME ANATGKEAED DNISVTIQAE
260 270 280 290 300
DAITLDFDGD DLLETGKNVK ITDSEASKPK DVQDAIAQSP EKEAKDYEMN
310 320 330 340 350
PNHKDGKKED SVKGEPVEKE ARESAKKAES GDKEKDTLKK GPSSTGASGQ
360 370 380 390 400
AKSSSKESKD SKTSSKDDKG STGSAGGSSG SSTKNIWVSG LSSNTKAADL
410 420 430 440 450
KNLFGKYGKV LSAKVVTNAR SPGAKCYGIV TMSSSTEVSR CVAHLHRTEL
460 470 480 490 500
HGQLISVEKV KGDPSKKEMK KENDEKSSSR SAGDKKNASD RSAKTQASIK
510 520 530 540 550
KEEKRSSEKS EKKESKDTKK IEKDEKNDDG PSGQTSESLK KSEEKKRISS
560 570 580 590 600
KSPGHMVILN QTKGDHCRPS RRGRYEKGHG RSKEKERASL DKKRDKDYRR
610 620 630 640 650
KEILPFEKMK EQRLREHLVR FERLKQAVEF RRRKEIAERE RRERERIRII
660 670 680 690 700
REREERERLQ RERERLEIER QKLERERMER ERLERERIRI EQERRREAER
710 720 730 740 750
IAREREELRR QQQQLRYEQE KRNSLKRPRD VDHRRDDPYW SENKKLSLDT
760 770 780 790 800
EARFGHGSDY RQQSRFLDFS HRERARFPDT ASVQSSFERR ERFVGQSEGK
810 820 830 840 850
KPRPAARREE PSFERYPKNF SDSRRNEPPP PRNELRETDR REVRGERDER
860 870 880 890 900
RTVILHDRPE VAHPRHPRET VPNPSRPTSW KSEANMSTEK RESRVERPER
910 920 930 940 950
SGREVSGHTV RGAPPGNRSS ASGYGTREGE RGVIADRGSG TQHYPEERHV
960 970 980 990 1000
VERHGRDTSG PRKEWHGPPS QGPSYHDTRR MGDGRAGAGM ITQHSSTASP
1010 1020 1030
VNRIVQMSGN SLPRGSSSGF KPFKSGPPRR F
Length:1,031
Mass (Da):116,919
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDBD3F617F816C79C
GO
Isoform 2 (identifier: Q8CH25-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     197-214: Missing.

Show »
Length:1,013
Mass (Da):115,179
Checksum:iF0D3C0E3C42E4FDE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1L1STF9A0A1L1STF9_MOUSE
SAFB-like transcription modulator
Sltm
664Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1L1SRL0A0A1L1SRL0_MOUSE
SAFB-like transcription modulator
Sltm
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH19992 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC32471 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAE22267 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti4A → R in BAB30967 (PubMed:16141072).Curated1
Sequence conflicti985R → Q in BAE22267 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_028834197 – 214Missing in isoform 2. 1 PublicationAdd BLAST18

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF462146 mRNA Translation: AAO15605.1
AK017839 mRNA Translation: BAB30967.1
AK045723 mRNA Translation: BAC32471.1 Different initiation.
AK077578 mRNA Translation: BAC36873.1
AK134756 mRNA Translation: BAE22267.1 Different initiation.
BC019992 mRNA Translation: AAH19992.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS23322.1 [Q8CH25-1]
CCDS90615.1 [Q8CH25-2]

NCBI Reference Sequences

More...
RefSeqi
NP_079966.2, NM_025690.3 [Q8CH25-1]
NP_080613.1, NM_026337.1 [Q8CH25-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000049263; ENSMUSP00000049112; ENSMUSG00000032212 [Q8CH25-1]
ENSMUST00000216816; ENSMUSP00000149059; ENSMUSG00000032212 [Q8CH25-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
66660

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:66660

UCSC genome browser

More...
UCSCi
uc009qok.1, mouse [Q8CH25-2]
uc009qol.1, mouse [Q8CH25-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF462146 mRNA Translation: AAO15605.1
AK017839 mRNA Translation: BAB30967.1
AK045723 mRNA Translation: BAC32471.1 Different initiation.
AK077578 mRNA Translation: BAC36873.1
AK134756 mRNA Translation: BAE22267.1 Different initiation.
BC019992 mRNA Translation: AAH19992.1 Different initiation.
CCDSiCCDS23322.1 [Q8CH25-1]
CCDS90615.1 [Q8CH25-2]
RefSeqiNP_079966.2, NM_025690.3 [Q8CH25-1]
NP_080613.1, NM_026337.1 [Q8CH25-2]

3D structure databases

SMRiQ8CH25
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi211628, 3 interactors
IntActiQ8CH25, 3 interactors
MINTiQ8CH25
STRINGi10090.ENSMUSP00000049112

PTM databases

iPTMnetiQ8CH25
PhosphoSitePlusiQ8CH25

Proteomic databases

jPOSTiQ8CH25
PaxDbiQ8CH25
PeptideAtlasiQ8CH25
PRIDEiQ8CH25

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
25331, 134 antibodies

Genome annotation databases

EnsembliENSMUST00000049263; ENSMUSP00000049112; ENSMUSG00000032212 [Q8CH25-1]
ENSMUST00000216816; ENSMUSP00000149059; ENSMUSG00000032212 [Q8CH25-2]
GeneIDi66660
KEGGimmu:66660
UCSCiuc009qok.1, mouse [Q8CH25-2]
uc009qol.1, mouse [Q8CH25-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79811
MGIiMGI:1913910, Sltm

Phylogenomic databases

eggNOGiKOG4661, Eukaryota
GeneTreeiENSGT00940000156573
HOGENOMiCLU_011145_1_0_1
InParanoidiQ8CH25
OMAiFRRGRYF
OrthoDBi803886at2759
PhylomeDBiQ8CH25
TreeFamiTF325240

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
66660, 5 hits in 20 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Sltm, mouse

Protein Ontology

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PROi
PR:Q8CH25
RNActiQ8CH25, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000032212, Expressed in forelimb bud and 307 other tissues
ExpressionAtlasiQ8CH25, baseline and differential
GenevisibleiQ8CH25, MM

Family and domain databases

Gene3Di1.10.720.30, 1 hit
3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
IPR003034, SAP_dom
IPR036361, SAP_dom_sf
IPR034780, SLTM
PANTHERiPTHR15683:SF5, PTHR15683:SF5, 1 hit
PfamiView protein in Pfam
PF00076, RRM_1, 1 hit
PF02037, SAP, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 1 hit
SM00513, SAP, 1 hit
SUPFAMiSSF54928, SSF54928, 1 hit
SSF68906, SSF68906, 1 hit
PROSITEiView protein in PROSITE
PS50102, RRM, 1 hit
PS50800, SAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSLTM_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CH25
Secondary accession number(s): Q3UYE5
, Q8BP76, Q8BR40, Q8VCF4, Q9CS57
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: March 1, 2003
Last modified: August 12, 2020
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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