UniProtKB - Q8CGN4 (BCOR_MOUSE)
BCL-6 corepressor
Bcor
Functioni
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2) (By similarity).
By similarity1 PublicationGO - Molecular functioni
- DNA-binding transcription factor binding Source: MGI
- heat shock protein binding Source: MGI
- histone deacetylase binding Source: MGI
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: MGI
- transcription cis-regulatory region binding Source: MGI
- transcription corepressor activity Source: MGI
- ubiquitin-protein transferase activity Source: Ensembl
GO - Biological processi
- blastocyst hatching Source: MGI
- chromatin organization Source: UniProtKB-KW
- heart development Source: MGI
- histone H2A monoubiquitination Source: MGI
- negative regulation of bone mineralization Source: MGI
- negative regulation of histone H3-K36 methylation Source: MGI
- negative regulation of histone H3-K4 methylation Source: MGI
- negative regulation of tooth mineralization Source: MGI
- negative regulation of transcription, DNA-templated Source: MGI
- negative regulation of transcription by RNA polymerase II Source: MGI
- odontogenesis Source: MGI
- roof of mouth development Source: MGI
- specification of axis polarity Source: MGI
Keywordsi
Molecular function | Chromatin regulator, Repressor |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: BCL-6 corepressorShort name: BCoR |
Gene namesi | Name:Bcor Synonyms:Kiaa1575 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1918708, Bcor |
VEuPathDBi | HostDB:ENSMUSG00000040363 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Nucleus
- BCOR complex Source: MGI
- nucleoplasm Source: MGI
- nucleus Source: MGI
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000066979 | 1 – 1759 | BCL-6 corepressorAdd BLAST | 1759 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 336 | PhosphoserineBy similarity | 1 | |
Modified residuei | 340 | PhosphoserineBy similarity | 1 | |
Modified residuei | 365 | PhosphoserineBy similarity | 1 | |
Modified residuei | 367 | PhosphoserineBy similarity | 1 | |
Modified residuei | 392 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 423 | PhosphoserineBy similarity | 1 | |
Cross-linki | 787 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Cross-linki | 873 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 1128 | PhosphothreonineCombined sources | 1 | |
Modified residuei | 1131 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1143 | PhosphoserineCombined sources | 1 | |
Cross-linki | 1259 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 1293 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1348 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1413 | PhosphoserineBy similarity | 1 | |
Cross-linki | 1417 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q8CGN4 |
jPOSTi | Q8CGN4 |
MaxQBi | Q8CGN4 |
PaxDbi | Q8CGN4 |
PeptideAtlasi | Q8CGN4 |
PRIDEi | Q8CGN4 |
ProteomicsDBi | 273445 [Q8CGN4-1] 273446 [Q8CGN4-2] 273447 [Q8CGN4-3] 273448 [Q8CGN4-4] |
PTM databases
iPTMneti | Q8CGN4 |
PhosphoSitePlusi | Q8CGN4 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSMUSG00000040363, Expressed in ectoplacental cone and 289 other tissues |
ExpressionAtlasi | Q8CGN4, baseline and differential |
Genevisiblei | Q8CGN4, MM |
Interactioni
Subunit structurei
Interacts with CPNE4 (via VWFA domain) (PubMed:12522145). Isoform 1 may interact with MLLT3/AF9 (PubMed:12776190).
Interacts with BCL6; the interaction is direct. Forms ternary complexes with BCL6 and SMRT/NCOR2 on selected target genes promoters; potently repress expression. Can interact with HDAC1, HDAC3 and HDAC5.
Interacts with PCGF1; the interaction is direct.
Interacts with KDM2B.
Component of an approximately 800 kDa repressive BCOR complex at least composed of BCOR, RYBP, PCGF1, RING1, RNF2/RING2, KDM2B and SKP1 (By similarity).
By similarity2 PublicationsBinary interactionsi
Q8CGN4
With | #Exp. | IntAct |
---|---|---|
Bcl6 [P41183] | 2 | EBI-1216174,EBI-6253762 |
GO - Molecular functioni
- DNA-binding transcription factor binding Source: MGI
- heat shock protein binding Source: MGI
- histone deacetylase binding Source: MGI
Protein-protein interaction databases
BioGRIDi | 214722, 10 interactors |
DIPi | DIP-29852N |
IntActi | Q8CGN4, 7 interactors |
MINTi | Q8CGN4 |
STRINGi | 10090.ENSMUSP00000111175 |
Miscellaneous databases
RNActi | Q8CGN4, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 1466 – 1499 | ANK 1Add BLAST | 34 | |
Repeati | 1500 – 1529 | ANK 2Add BLAST | 30 | |
Repeati | 1533 – 1562 | ANK 3Add BLAST | 30 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 100 – 120 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 399 – 432 | DisorderedSequence analysisAdd BLAST | 34 | |
Regioni | 498 – 514 | Interaction with BCL6By similarityAdd BLAST | 17 | |
Regioni | 540 – 635 | DisorderedSequence analysisAdd BLAST | 96 | |
Regioni | 739 – 795 | DisorderedSequence analysisAdd BLAST | 57 | |
Regioni | 1079 – 1190 | DisorderedSequence analysisAdd BLAST | 112 | |
Regioni | 1222 – 1334 | DisorderedSequence analysisAdd BLAST | 113 | |
Regioni | 1397 – 1456 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 1612 – 1635 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 1638 – 1752 | Necessary and sufficient for interaction with PCGF1By similarityAdd BLAST | 115 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 103 – 120 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 540 – 621 | Polar residuesSequence analysisAdd BLAST | 82 | |
Compositional biasi | 739 – 764 | Basic and acidic residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 1079 – 1109 | Basic and acidic residuesSequence analysisAdd BLAST | 31 | |
Compositional biasi | 1132 – 1183 | Basic and acidic residuesSequence analysisAdd BLAST | 52 | |
Compositional biasi | 1242 – 1256 | Polar residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 1257 – 1278 | Basic and acidic residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 1294 – 1320 | Polar residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 1429 – 1452 | Polar residuesSequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
eggNOGi | ENOG502RZ5N, Eukaryota |
GeneTreei | ENSGT00940000153737 |
HOGENOMi | CLU_003863_0_0_1 |
InParanoidi | Q8CGN4 |
OMAi | CTEEKHP |
OrthoDBi | 85469at2759 |
PhylomeDBi | Q8CGN4 |
TreeFami | TF333317 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit 3.10.260.40, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR031628, BCOR IPR032365, PUFD IPR038227, PUFD_som_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF15808, BCOR, 1 hit PF16553, PUFD, 1 hit |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
s (4+)i Sequence
Sequence statusi: Complete.
This entry describes 4 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLSATPLYGN VHSWMNSERV RMCGTSEDRK IPVNDGDASK ARLELREETP
60 70 80 90 100
LSHSVVDTSG AHRIDGLAAL SMDRTGLIRE GLRVPGNIVY SGLCGLGSEK
110 120 130 140 150
GREATPSSLS GLGFSSERNP EMQFKPNTPE TVEASAVSGK PPNGFSAIYK
160 170 180 190 200
TPPGIQKSAV ATAESLGLDR PASDKQSPLN INGASYLRLP WVNPYMEGAT
210 220 230 240 250
PAIYPFLDSP NKYSLNMYKA LLPQQSYGLA QPLYSPVCTS GERFLYLPPP
260 270 280 290 300
HYVNPHIPSS LASPMRLSTP SASAAIPPLV HCSDKSLPWK MGVNPGNPVD
310 320 330 340 350
SHSYPHIQNS KQPRVTSAKA VNSGLPGDTA LLLPPSPRPS ARVHLPTQPA
360 370 380 390 400
AETYSEFHKH YPRISTSPSV TLTKPYMTAN SEFSTSRLSN GKYPKALDGG
410 420 430 440 450
DCAQSMPGHT RKTTVQDRKD GGSPPLLEKQ TVTKDVTDKP LDLSSKVVDA
460 470 480 490 500
DASKGDHMKK MAPTVLVHSR AASGLVLSGS EIPKETLSPP GNGCSIYRSE
510 520 530 540 550
IISTAPSSWV VPGPSPNEEN NGKSLSLKNK ALDWAIPQQR SSSCPRMGGT
560 570 580 590 600
DAVVTNVSGS VSSSGRPASA SPAPNANANA DGTKTSRSSV DTTPSVIQHV
610 620 630 640 650
GQPSSTPAKH GGSTSSKGAK ANPEPSFKAS ENGLPPTSIF LSPNEAFRSP
660 670 680 690 700
AIPYPRSYLP YAAPEGIALS PLSLHGKGPV YPHPVLLPNG SLFPGHLAPK
710 720 730 740 750
PGLPYGLHTS RPEFVTYQDA LGLGMVHPML IPHTPIEITK EEKPERRSRS
760 770 780 790 800
HERARYEDPT LRSRFSEMLE ASSTKLHPEV PTDKNLKPNS SWNQGKTGVK
810 820 830 840 850
SDKLVYVDLL REEADTKTDA GAPKAGLVAE NVGQDTEATK PSADPVIQQR
860 870 880 890 900
REFISLREEL GRITDFHESF TFKQASSQPV FSLGKDSGAA GTNKENLGVQ
910 920 930 940 950
VATPFLETAL GSEGPAVTFG KTQEDPKPFC VGGAPPNMDV TPAYTKEGTD
960 970 980 990 1000
EAESNDGKVL KPKPSKLAKR IANSAGYVGD RFKCVTTELY ADSSQLSREQ
1010 1020 1030 1040 1050
RALQMEGLQE DSILCLPAAY CERAMMRFSE LEMKEREGSH PATKDSEVCK
1060 1070 1080 1090 1100
FSPADWERLK GNQEKKPKSV TLEEAIADQN DSERCEYSTG NKHDLFEAPE
1110 1120 1130 1140 1150
DKDLPVEKYF LERPPVSEPP SDQGVVDTPH SPTLRLDRKR KLSGDSTHTE
1160 1170 1180 1190 1200
TAVEELAEDP LKAKRRRISK DDWPEREMTN SSSNHLEDPH CNELTNLKVC
1210 1220 1230 1240 1250
IELTGLHPKK QRHLLHLRER WEQQVSAAES KPGRQSRKEV AQAVQPEVTS
1260 1270 1280 1290 1300
QGTNITEEKP GRKKAEAKGN RGWSEESLKS CDNEQGLPVL SGSPPMKSLS
1310 1320 1330 1340 1350
STNASGKKQT QPSCTPASRL PAKQQKIKES QKTDVLCTGE DEDCQAASPL
1360 1370 1380 1390 1400
QKYTDNIEKP SGKRLCKTKH LIPQESRRSL QITGDYYVEN TDTKMTVRRF
1410 1420 1430 1440 1450
RKRPEPSSDY DLSPPAKQEP KPFDRLQQLL PATQATQLPR SNSPQETTQS
1460 1470 1480 1490 1500
RPMPPEARRL IVNKNAGETL LQRAARLGYE EVVLYCLENK VCDVNHRDNA
1510 1520 1530 1540 1550
GYCALHEACA RGWLNIVRHL LEYGADVNCS AQDGTRPLHD AVENDHLEIV
1560 1570 1580 1590 1600
RLLLSYGADP TLATYSGRTI MKMTHSELME KFLTDYLNDL QGRSEDDTSG
1610 1620 1630 1640 1650
AWEFYGSSVC EPDDESGYDV LANPPGPEDP DEEEDTYSDL FEFEFAESSL
1660 1670 1680 1690 1700
LPCYNIQVSV AQGPRNWLLL SDVLKKLKMS SRIFRSNFPN LEIVTIAEAE
1710 1720 1730 1740 1750
FYRQVSTSLL FSCPKDLEAF NPESKELLDL VEFTNELQTL LGSSVEWLHP
SDTGHENYW
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF7BEN2 | F7BEN2_MOUSE | BCL-6 corepressor | Bcor | 125 | Annotation score: | ||
F6XPR4 | F6XPR4_MOUSE | BCL-6 corepressor | Bcor | 95 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 161 | A → V in AAN85318 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 161 | A → V in AAN85319 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 161 | A → V in AAN85320 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 161 | A → V in AAN85321 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 167 | G → S in AAN85318 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 167 | G → S in AAN85319 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 167 | G → S in AAN85320 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 167 | G → S in AAN85321 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 731 | I → V in AAN85318 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 731 | I → V in AAN85319 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 731 | I → V in AAN85320 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 731 | I → V in AAN85321 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 852 | E → D in BAC35338 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 1424 | D → G in AAN85318 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 1424 | D → G in AAN85319 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 1424 | D → G in AAN85320 (PubMed:12776190).Curated | 1 | |
Sequence conflicti | 1424 | D → G in AAN85321 (PubMed:12776190).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_012558 | 1005 – 1022 | Missing in isoform 2 and isoform 4. 2 PublicationsAdd BLAST | 18 | |
Alternative sequenceiVSP_012559 | 1171 – 1204 | Missing in isoform 3 and isoform 4. 3 PublicationsAdd BLAST | 34 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY161170 mRNA Translation: AAN85318.1 AY161171 mRNA Translation: AAN85319.1 AY161172 mRNA Translation: AAN85320.1 AY161173 mRNA Translation: AAN85321.1 AK129398 mRNA Translation: BAC98208.1 Different initiation. AL808012 Genomic DNA No translation available. BC058656 mRNA Translation: AAH58656.1 AK053309 mRNA Translation: BAC35338.1 |
CCDSi | CCDS30021.1 [Q8CGN4-3] CCDS30022.1 [Q8CGN4-4] CCDS40872.1 [Q8CGN4-2] CCDS40873.1 [Q8CGN4-1] |
RefSeqi | NP_001161793.1, NM_001168321.1 [Q8CGN4-4] NP_083786.2, NM_029510.3 [Q8CGN4-1] NP_778209.2, NM_175044.3 [Q8CGN4-2] NP_778210.2, NM_175045.3 [Q8CGN4-3] NP_778211.2, NM_175046.3 [Q8CGN4-4] XP_017174110.1, XM_017318621.1 [Q8CGN4-1] XP_017174111.1, XM_017318622.1 [Q8CGN4-1] XP_017174112.1, XM_017318623.1 [Q8CGN4-1] XP_017174113.1, XM_017318624.1 [Q8CGN4-1] |
Genome annotation databases
Ensembli | ENSMUST00000043441; ENSMUSP00000048024; ENSMUSG00000040363 [Q8CGN4-4] ENSMUST00000065143; ENSMUSP00000068618; ENSMUSG00000040363 [Q8CGN4-3] ENSMUST00000115512; ENSMUSP00000111174; ENSMUSG00000040363 [Q8CGN4-2] ENSMUST00000115513; ENSMUSP00000111175; ENSMUSG00000040363 [Q8CGN4-1] ENSMUST00000124033; ENSMUSP00000116258; ENSMUSG00000040363 [Q8CGN4-4] |
GeneIDi | 71458 |
KEGGi | mmu:71458 |
UCSCi | uc009sqq.2, mouse [Q8CGN4-1] uc009sqr.2, mouse [Q8CGN4-3] uc009sqs.2, mouse [Q8CGN4-2] uc009sqt.2, mouse [Q8CGN4-4] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY161170 mRNA Translation: AAN85318.1 AY161171 mRNA Translation: AAN85319.1 AY161172 mRNA Translation: AAN85320.1 AY161173 mRNA Translation: AAN85321.1 AK129398 mRNA Translation: BAC98208.1 Different initiation. AL808012 Genomic DNA No translation available. BC058656 mRNA Translation: AAH58656.1 AK053309 mRNA Translation: BAC35338.1 |
CCDSi | CCDS30021.1 [Q8CGN4-3] CCDS30022.1 [Q8CGN4-4] CCDS40872.1 [Q8CGN4-2] CCDS40873.1 [Q8CGN4-1] |
RefSeqi | NP_001161793.1, NM_001168321.1 [Q8CGN4-4] NP_083786.2, NM_029510.3 [Q8CGN4-1] NP_778209.2, NM_175044.3 [Q8CGN4-2] NP_778210.2, NM_175045.3 [Q8CGN4-3] NP_778211.2, NM_175046.3 [Q8CGN4-4] XP_017174110.1, XM_017318621.1 [Q8CGN4-1] XP_017174111.1, XM_017318622.1 [Q8CGN4-1] XP_017174112.1, XM_017318623.1 [Q8CGN4-1] XP_017174113.1, XM_017318624.1 [Q8CGN4-1] |
3D structure databases
AlphaFoldDBi | Q8CGN4 |
SMRi | Q8CGN4 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 214722, 10 interactors |
DIPi | DIP-29852N |
IntActi | Q8CGN4, 7 interactors |
MINTi | Q8CGN4 |
STRINGi | 10090.ENSMUSP00000111175 |
PTM databases
iPTMneti | Q8CGN4 |
PhosphoSitePlusi | Q8CGN4 |
Proteomic databases
EPDi | Q8CGN4 |
jPOSTi | Q8CGN4 |
MaxQBi | Q8CGN4 |
PaxDbi | Q8CGN4 |
PeptideAtlasi | Q8CGN4 |
PRIDEi | Q8CGN4 |
ProteomicsDBi | 273445 [Q8CGN4-1] 273446 [Q8CGN4-2] 273447 [Q8CGN4-3] 273448 [Q8CGN4-4] |
Protocols and materials databases
Antibodypediai | 24949, 295 antibodies from 34 providers |
DNASUi | 71458 |
Genome annotation databases
Ensembli | ENSMUST00000043441; ENSMUSP00000048024; ENSMUSG00000040363 [Q8CGN4-4] ENSMUST00000065143; ENSMUSP00000068618; ENSMUSG00000040363 [Q8CGN4-3] ENSMUST00000115512; ENSMUSP00000111174; ENSMUSG00000040363 [Q8CGN4-2] ENSMUST00000115513; ENSMUSP00000111175; ENSMUSG00000040363 [Q8CGN4-1] ENSMUST00000124033; ENSMUSP00000116258; ENSMUSG00000040363 [Q8CGN4-4] |
GeneIDi | 71458 |
KEGGi | mmu:71458 |
UCSCi | uc009sqq.2, mouse [Q8CGN4-1] uc009sqr.2, mouse [Q8CGN4-3] uc009sqs.2, mouse [Q8CGN4-2] uc009sqt.2, mouse [Q8CGN4-4] |
Organism-specific databases
CTDi | 54880 |
MGIi | MGI:1918708, Bcor |
VEuPathDBi | HostDB:ENSMUSG00000040363 |
Rougei | Search... |
Phylogenomic databases
eggNOGi | ENOG502RZ5N, Eukaryota |
GeneTreei | ENSGT00940000153737 |
HOGENOMi | CLU_003863_0_0_1 |
InParanoidi | Q8CGN4 |
OMAi | CTEEKHP |
OrthoDBi | 85469at2759 |
PhylomeDBi | Q8CGN4 |
TreeFami | TF333317 |
Miscellaneous databases
BioGRID-ORCSi | 71458, 6 hits in 80 CRISPR screens |
ChiTaRSi | Bcor, mouse |
PROi | PR:Q8CGN4 |
RNActi | Q8CGN4, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000040363, Expressed in ectoplacental cone and 289 other tissues |
ExpressionAtlasi | Q8CGN4, baseline and differential |
Genevisiblei | Q8CGN4, MM |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit 3.10.260.40, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR031628, BCOR IPR032365, PUFD IPR038227, PUFD_som_sf |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF15808, BCOR, 1 hit PF16553, PUFD, 1 hit |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | BCOR_MOUSE | |
Accessioni | Q8CGN4Primary (citable) accession number: Q8CGN4 Secondary accession number(s): B1AXK3 Q8CGN3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 4, 2005 |
Last sequence update: | January 4, 2005 | |
Last modified: | May 25, 2022 | |
This is version 153 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families