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Entry version 135 (29 Sep 2021)
Sequence version 1 (01 Mar 2003)
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Protein

Retinitis pigmentosa 1-like 1 protein

Gene

Rp1l1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation, Sensory transduction, Vision

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Retinitis pigmentosa 1-like 1 protein
Alternative name(s):
Retinitis pigmentosa 1-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rp1l1
Synonyms:Rp1hl1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2384303, Rp1l1

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000046049

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Mice display scattered outer segment disorganization, reduced electroretinogram amplitudes, and progressive photoreceptor degeneration. In single rods defective cells photosensitivity is reduced. Rp1 and Rp1l1 double heterozygotes exhibits abnormal outer segment morphology and reduced single rod photosensitivity and dark currents, while individual heterozygotes are normal.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000974071 – 1859Retinitis pigmentosa 1-like 1 proteinAdd BLAST1859

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CGM2

PRoteomics IDEntifications database

More...
PRIDEi
Q8CGM2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
260832

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CGM2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CGM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Retinal-specific; expressed in photoreceptor.

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected in retina at birth but not at prenatal stages.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000046049, Expressed in retinal neural layer and 14 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8CGM2, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RP1; has a synergistic effect with RP1 in photoreceptor differentiation.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
234831, 3 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000055449

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CGM2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CGM2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 126Doublecortin 1PROSITE-ProRule annotationAdd BLAST85
Domaini160 – 239Doublecortin 2PROSITE-ProRule annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 22DisorderedSequence analysisAdd BLAST22
Regioni115 – 154DisorderedSequence analysisAdd BLAST40
Regioni263 – 301DisorderedSequence analysisAdd BLAST39
Regioni426 – 445DisorderedSequence analysisAdd BLAST20
Regioni457 – 593DisorderedSequence analysisAdd BLAST137
Regioni700 – 750DisorderedSequence analysisAdd BLAST51
Regioni868 – 920DisorderedSequence analysisAdd BLAST53
Regioni952 – 997DisorderedSequence analysisAdd BLAST46
Regioni1152 – 1211DisorderedSequence analysisAdd BLAST60
Regioni1227 – 1255DisorderedSequence analysisAdd BLAST29
Regioni1298 – 1350DisorderedSequence analysisAdd BLAST53
Regioni1567 – 1859DisorderedSequence analysisAdd BLAST293

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi279 – 293Polar residuesSequence analysisAdd BLAST15
Compositional biasi457 – 476Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi500 – 517Polar residuesSequence analysisAdd BLAST18
Compositional biasi532 – 547Polar residuesSequence analysisAdd BLAST16
Compositional biasi562 – 593Polar residuesSequence analysisAdd BLAST32
Compositional biasi709 – 750Polar residuesSequence analysisAdd BLAST42
Compositional biasi868 – 885Polar residuesSequence analysisAdd BLAST18
Compositional biasi1152 – 1179Polar residuesSequence analysisAdd BLAST28
Compositional biasi1333 – 1350Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi1608 – 1632Basic and acidic residuesSequence analysisAdd BLAST25
Compositional biasi1697 – 1720Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi1721 – 1741Polar residuesSequence analysisAdd BLAST21
Compositional biasi1752 – 1782Polar residuesSequence analysisAdd BLAST31
Compositional biasi1793 – 1809Basic and acidic residuesSequence analysisAdd BLAST17

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3757, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154242

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001096_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CGM2

Identification of Orthologs from Complete Genome Data

More...
OMAi
PCPQRRS

Database of Orthologous Groups

More...
OrthoDBi
79495at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CGM2

TreeFam database of animal gene trees

More...
TreeFami
TF318770

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.20.230, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003533, Doublecortin_dom
IPR036572, Doublecortin_dom_sf
IPR040163, RP1/RP1L1/DCX

The PANTHER Classification System

More...
PANTHERi
PTHR23005, PTHR23005, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03607, DCX, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00537, DCX, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF89837, SSF89837, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50309, DC, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q8CGM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSTPGDTRD APAPSHPAPS HRQCLLPSVA HTPSVTEVTP AKKITFLKRG
60 70 80 90 100
DPQFAGVRLA VHQRTFKTFS SLMDELSQRM PLSFGVRSVT TPRGLHGLSA
110 120 130 140 150
LEQLQDGGCY LCSDRKPPKT SREPGRLQRK SPSAGQAQVF QGGHEAPETS
160 170 180 190 200
YSWKGPVAPR RLTLVKNGDP RRQQTVVLSH KNTRSLAAFL GKASELLRFP
210 220 230 240 250
VKQVYTTRGK KVDSLQTLLD GPSVLVCAGN EAFRCLEMEN DRGNRTRKLS
260 270 280 290 300
SVTARSERGC WGPNAKQSVI HSRGRSGGKL RQVSLTSERS GLSDHPASGH
310 320 330 340 350
RAWAGPALDR CPQDMPVPPG SLVAADDVEK KVCMNEDGSL SVEMKVRFQL
360 370 380 390 400
LGEDTLRWSQ RVGQASVFTA ASGKGQDPRE ADRFCCRQEG YPWGILKPGA
410 420 430 440 450
QGLGSYDGGC QEAFDVGQKS QPSYDIWRNP LATPEGTGPT PRRRWGLAKL
460 470 480 490 500
SGCKSHWRQE ANHRKGHDKD NLSRVSTPRH PRSVQPGSCC PWTPDGDTGS
510 520 530 540 550
DTLHPVSSAS SHNETDLESG EGLCLEDTGP HGSRPETQST ERALSDTSVS
560 570 580 590 600
AKSREESSEG GGQLHRSSSQ ARVMASREQV TKGDNPCIST QSHLPLNHMG
610 620 630 640 650
LQTEKYRQGT RGWEVSGEPE LRLALVPGHS GSQDTQRDAL PAPACAPAQW
660 670 680 690 700
RQRKQKRPAS VECLPSVSVP YQVAQKGHAR QDHYYRDTQS SLDTALQMPM
710 720 730 740 750
PQEREQACPG SPAPQSPSNS PSAGNQASED LRSPFSSSLD LQEPQATSKA
760 770 780 790 800
TTIAVSGSDC VCHSTRSVEP AGDTKCQAHS STPTPAHRGE LGCLWDKAGT
810 820 830 840 850
TPEPFSFSVL LDRCPEADDP RTYHDCCCLQ AVPSSPLAAP SGQTQTSISE
860 870 880 890 900
ACLGGSSFCP TPPKEQTCFG RESASNGSTS SGHSRADGFA GPRRTLLVKS
910 920 930 940 950
PGVRGSLEER EADGGVTPSA LPYASPDAVV REWLGNIPEK PVLMTYEMAD
960 970 980 990 1000
ENTEVPSDGP EGPKEDSLKV LGEPSQAKQQ PPEGATNEHP EPAGVLSGPG
1010 1020 1030 1040 1050
SVCCRLGGDL HPDATSGERL KAPAEAGIGE GARVDHGVSL CALPTKVAAS
1060 1070 1080 1090 1100
TQIMKALLGS KPGRPSSLPE VSSTVAQRLS SSAGAFIACL ARLHFFDESL
1110 1120 1130 1140 1150
GPLDGKVRLE ESPKYQEMLR LFQTLWPGSE LWQGQLDFSL RKLTSHQALL
1160 1170 1180 1190 1200
GTEDFTPTSS SGVDVSSGSG GSGESSVPCV MDNTLAPEKR DLPLKIPSQR
1210 1220 1230 1240 1250
PDSRNQGYPE LVGHSTVSSV SQVRACATGG EETGKGGRKQ TWGNAPEQSV
1260 1270 1280 1290 1300
HSTMLEGDAL SEETEGRVRE RLQENSVHGK GLPEEGVRVC SQEMLAAGSQ
1310 1320 1330 1340 1350
DGAGSPEDTR VPTDEAGADA ASGGLWPLDG REEPTESPQH FSESNSRVRE
1360 1370 1380 1390 1400
HQSAHKLELG LEEVSRLDAR GCKQACIKAS SGTMAHKGSL DPDPIWVSKL
1410 1420 1430 1440 1450
LKKIEKAFMA HLADATAELR ARWDLHDNHL LDQMVTELEQ DVGRRLQAST
1460 1470 1480 1490 1500
VMEVRKIQSR AGRMVPEPPR EALRGQASLQ TEQRRRRLQG LRNFSAVPGQ
1510 1520 1530 1540 1550
GPLSLTLEDG PTLKTALGTK SGAEPAEDEF CPCEICLKKK RTPRFPKDAA
1560 1570 1580 1590 1600
TVSGAPVRKA FDLQQILQSK KGGSSNREAM EVAPQRTGRM LSQEDLGTVQ
1610 1620 1630 1640 1650
GADEKQGLGV AEGEEGEGKQ RLRAEEDPEI LKTEGSGCCA PEEDEATEED
1660 1670 1680 1690 1700
GEICIGTAQE SQQLEGTEMG KEGTLPQSFR DGGTLEAPAR QGTHSVEIQE
1710 1720 1730 1740 1750
ASRERQQEVE GRHQDVKEDS PWVSSGESQG RVGSENTSLD QEGRLLNHHQ
1760 1770 1780 1790 1800
RPGPQSHHTA CSSRALSLDN SSQVSQKGSD GDLTSGDLKC TKAKNSRVLH
1810 1820 1830 1840 1850
AEKKVPVMYP ERSSSEQEVP SSPRLPKQGK GEDEGSAGSL ACTQVGGKVD

GFGQDDLDF
Length:1,859
Mass (Da):199,686
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iED885DA0FAF6E6E9
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH31365 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY168340 mRNA Translation: AAN86958.1
AJ491325 mRNA Translation: CAD36958.1
BC031365 mRNA Translation: AAH31365.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36951.1

NCBI Reference Sequences

More...
RefSeqi
NP_666358.2, NM_146246.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000058229; ENSMUSP00000055449; ENSMUSG00000046049

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
271209

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:271209

UCSC genome browser

More...
UCSCi
uc007uia.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY168340 mRNA Translation: AAN86958.1
AJ491325 mRNA Translation: CAD36958.1
BC031365 mRNA Translation: AAH31365.1 Different initiation.
CCDSiCCDS36951.1
RefSeqiNP_666358.2, NM_146246.3

3D structure databases

SMRiQ8CGM2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi234831, 3 interactors
STRINGi10090.ENSMUSP00000055449

PTM databases

iPTMnetiQ8CGM2
PhosphoSitePlusiQ8CGM2

Proteomic databases

PaxDbiQ8CGM2
PRIDEiQ8CGM2
ProteomicsDBi260832

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
77523, 8 antibodies

Genome annotation databases

EnsembliENSMUST00000058229; ENSMUSP00000055449; ENSMUSG00000046049
GeneIDi271209
KEGGimmu:271209
UCSCiuc007uia.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
94137
MGIiMGI:2384303, Rp1l1
VEuPathDBiHostDB:ENSMUSG00000046049

Phylogenomic databases

eggNOGiKOG3757, Eukaryota
GeneTreeiENSGT00940000154242
HOGENOMiCLU_001096_0_0_1
InParanoidiQ8CGM2
OMAiPCPQRRS
OrthoDBi79495at2759
PhylomeDBiQ8CGM2
TreeFamiTF318770

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
271209, 2 hits in 61 CRISPR screens

Protein Ontology

More...
PROi
PR:Q8CGM2
RNActiQ8CGM2, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000046049, Expressed in retinal neural layer and 14 other tissues
ExpressionAtlasiQ8CGM2, baseline and differential

Family and domain databases

Gene3Di3.10.20.230, 2 hits
InterProiView protein in InterPro
IPR003533, Doublecortin_dom
IPR036572, Doublecortin_dom_sf
IPR040163, RP1/RP1L1/DCX
PANTHERiPTHR23005, PTHR23005, 1 hit
PfamiView protein in Pfam
PF03607, DCX, 2 hits
SMARTiView protein in SMART
SM00537, DCX, 2 hits
SUPFAMiSSF89837, SSF89837, 2 hits
PROSITEiView protein in PROSITE
PS50309, DC, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRP1L1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CGM2
Secondary accession number(s): Q8K0I4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: March 1, 2003
Last modified: September 29, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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