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Entry version 113 (17 Jun 2020)
Sequence version 1 (01 Mar 2003)
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Protein

Coiled-coil and C2 domain-containing protein 2A

Gene

Cc2d2a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5620912 Anchoring of the basal body to the plasma membrane

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil and C2 domain-containing protein 2A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cc2d2a
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1924487 Cc2d2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell projection, Cilium, Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Embryos show randomized left-right axes, holoprosencephaly, microphthalmia and a variably expressive curved body axis. Cc2d2a null embryos also have cilia defects, which are exemplified by the absence of Arl13b staining in neural tube and surrounding mesenchyme.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003172511 – 1633Coiled-coil and C2 domain-containing protein 2AAdd BLAST1633

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CFW7

PRoteomics IDEntifications database

More...
PRIDEi
Q8CFW7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CFW7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CFW7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000039765 Expressed in retina and 226 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8CFW7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the tectonic-like complex (also named B9 complex).

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
231096, 2 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q8CFW7

Protein interaction database and analysis system

More...
IntActi
Q8CFW7, 7 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000048320

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CFW7 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CFW7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1031 – 1209C2PROSITE-ProRule annotationAdd BLAST179

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili440 – 501Sequence analysisAdd BLAST62
Coiled coili554 – 611Sequence analysisAdd BLAST58

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi240 – 243Poly-Glu4

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3639 Eukaryota
ENOG410XQVY LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155482

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001707_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CFW7

KEGG Orthology (KO)

More...
KOi
K19352

Identification of Orthologs from Complete Genome Data

More...
OMAi
NPIRTHQ

Database of Orthologous Groups

More...
OrthoDBi
246535at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CFW7

TreeFam database of animal gene trees

More...
TreeFami
TF324786

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000008 C2_dom
IPR028928 CC2D2AN-C2
IPR041510 DUF5523

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168 C2, 1 hit
PF15625 CC2D2AN-C2, 1 hit
PF17661 DUF5523, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239 C2, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004 C2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CFW7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNTNDEKMKI ISEDFTGDGV DTEAGRRKKN SKVRRQQRKK KPPASPPEEM
60 70 80 90 100
VSDKFQDGGQ QEVVEEEPET NLLSLTARRG PRSLPPIPSA SRTGFAEFSM
110 120 130 140 150
RERMREKLQA ARSKAESALL RDVPTPRPRR LRSPSREKET ETEFGTEPST
160 170 180 190 200
EVQDTQKEDD TKSYSRIKFR DSVRKIKSKP QLPPGFPSAE EAYNFFTFNF
210 220 230 240 250
DPEPEESEEK SPVKGGERAH HEDQEGEEGT QAQERAKKTE EEELLNGKDA
260 270 280 290 300
EDFLLGLDPT AHDFVAVRAA EYKSARIQLQ KEKEILFTPS RLTVPTYKKL
310 320 330 340 350
PENIQPRFLE DEGLYIGARP EVARTNENIM ENRLLIQEPG SKWFGDDGRI
360 370 380 390 400
LALPSPIKPF PSRPSLTTRE QSPKAGLETL YKKAEKYVHS RQHMIGSGDP
410 420 430 440 450
PGNFQLDIDI SGLIFTHHPC FSREHVLASK LAQLYDQYLA RQQRNKTKFL
460 470 480 490 500
TDKLQALRKA VQTSLNPEKP HQSLDTTQKT INEYKSEIRQ TRKLRDAEQE
510 520 530 540 550
KDRTLLKTII KVWKEMKSLR EFQRFTNTPL KLVLRKEKVD PKLDEDAYEA
560 570 580 590 600
EIQAEIHELL EEHMEEYATK MEEYRTSHQQ WKAWRKAQRA KKKKKKQTTE
610 620 630 640 650
EHLEEEEAEE SFPEEEVTKP IPPEPTDPAV IEQQVRERAA HSRRRPGEPT
660 670 680 690 700
LIPELSLAGN VTPNDQCPRV EVSRREDVRR RSVYLKVVFN SKEVSRTVSR
710 720 730 740 750
PLGADFRVHF GQIFNLQIFN WPESLMLQVY ETIGHSGTTL LAEVFLPIPE
760 770 780 790 800
TTLVTGRAPI EEVEFSSNQH VTLDHEGVGS GVPFSFEADG SNQLTLMTSG
810 820 830 840 850
KVSHSVAWAV GENGIPLIPP LSQQNIGFRS ALRRADAISS IGTSGLTDMK
860 870 880 890 900
KLAKWAAESK LDPNDPNHAP LMQLISVATS GESYVPDFFR LEQLQQEFNF
910 920 930 940 950
VSEEELNRSK RFRLLHLRSQ EVPEFRNYKQ IPAYDREIME KVFQDYEKRL
960 970 980 990 1000
RDRNVIETKD HLDMHRATVA KYLQQVREAV VNRFLTAKHH FLLTDLVVEE
1010 1020 1030 1040 1050
EVPNISSEGS GILGLSLFKL AEQKRPLRPR RKGRKKVTAQ NLSDGDIKLL
1060 1070 1080 1090 1100
VNIIRAYDIP VRKPVVSKFQ QPSRSSRTFS EKQTASPSTH SPLHNADYPL
1110 1120 1130 1140 1150
GQVLVRPFVE VSFQRTICHT TTAEGPNPSW NEELELPFRA PNGDYSTASL
1160 1170 1180 1190 1200
QSVKDDVYIN IFDEVLYDIL EDDRERGSGI HTRIERHWLG CVKIPFSTIY
1210 1220 1230 1240 1250
FQARIDGTFK IDIPPVLLGY SKERNIIMER AFDSARSLSE GSYITLFITI
1260 1270 1280 1290 1300
EPQLVPGEPM REKMSDMLKK FDTQEDEKLL QATEKFQAEC ALKFPQRQCL
1310 1320 1330 1340 1350
TTVTDMTGKT VFITRYLKPL NPPQELLHVY PNNPQATAEL VARYVSLIPF
1360 1370 1380 1390 1400
LPDSVSFAGV CDLWSTSDQF LDLLAGDEEE HAVLLCNYFL FLGKKAWLVM
1410 1420 1430 1440 1450
GSAIPEGPTA YVLTWEKNYY LIWNPCSGHC YGQFDAFCPL KSVGCLIGPD
1460 1470 1480 1490 1500
NIWFNIQHHD SPLRINFDVT KPKLWKSFFS RSLPYPGLSS VQPEELIYQH
1510 1520 1530 1540 1550
TDKAVAAELQ DRIEKILKEK IMDWRPRHLT RWNRYCTSTL RHFLPLLERS
1560 1570 1580 1590 1600
QGEDIEDDHR AELLKQLGDY RFSGFPLHMP YSEVKPLVEA VYSTGVHNID
1610 1620 1630
LPNVEFALAV YIHPYPKNVL SVWIYVASLV RNR
Length:1,633
Mass (Da):187,530
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i33C9B365385B7BFB
GO
Isoform 2 (identifier: Q8CFW7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-49: Missing.

Show »
Length:1,584
Mass (Da):181,918
Checksum:iB419223CC2DBAF03
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6YZ61F6YZ61_MOUSE
Coiled-coil and C2 domain-containin...
Cc2d2a
1,457Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti345G → E in BAC36933 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0309251 – 49Missing in isoform 2. 1 PublicationAdd BLAST49

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC032290 mRNA Translation: AAH32290.1
AK077658 mRNA Translation: BAC36933.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39080.1 [Q8CFW7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_758478.1, NM_172274.2 [Q8CFW7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000048150; ENSMUSP00000048320; ENSMUSG00000039765 [Q8CFW7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
231214

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:231214

UCSC genome browser

More...
UCSCi
uc008xhp.2 mouse [Q8CFW7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC032290 mRNA Translation: AAH32290.1
AK077658 mRNA Translation: BAC36933.1
CCDSiCCDS39080.1 [Q8CFW7-1]
RefSeqiNP_758478.1, NM_172274.2 [Q8CFW7-1]

3D structure databases

SMRiQ8CFW7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi231096, 2 interactors
CORUMiQ8CFW7
IntActiQ8CFW7, 7 interactors
STRINGi10090.ENSMUSP00000048320

PTM databases

iPTMnetiQ8CFW7
PhosphoSitePlusiQ8CFW7

Proteomic databases

PaxDbiQ8CFW7
PRIDEiQ8CFW7

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
50288 24 antibodies

Genome annotation databases

EnsembliENSMUST00000048150; ENSMUSP00000048320; ENSMUSG00000039765 [Q8CFW7-1]
GeneIDi231214
KEGGimmu:231214
UCSCiuc008xhp.2 mouse [Q8CFW7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57545
MGIiMGI:1924487 Cc2d2a

Phylogenomic databases

eggNOGiKOG3639 Eukaryota
ENOG410XQVY LUCA
GeneTreeiENSGT00940000155482
HOGENOMiCLU_001707_0_0_1
InParanoidiQ8CFW7
KOiK19352
OMAiNPIRTHQ
OrthoDBi246535at2759
PhylomeDBiQ8CFW7
TreeFamiTF324786

Enzyme and pathway databases

ReactomeiR-MMU-5620912 Anchoring of the basal body to the plasma membrane

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
231214 3 hits in 12 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Cc2d2a mouse

Protein Ontology

More...
PROi
PR:Q8CFW7
RNActiQ8CFW7 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000039765 Expressed in retina and 226 other tissues
GenevisibleiQ8CFW7 MM

Family and domain databases

InterProiView protein in InterPro
IPR000008 C2_dom
IPR028928 CC2D2AN-C2
IPR041510 DUF5523
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF15625 CC2D2AN-C2, 1 hit
PF17661 DUF5523, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
PROSITEiView protein in PROSITE
PS50004 C2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiC2D2A_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CFW7
Secondary accession number(s): Q8BP57
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2003
Last modified: June 17, 2020
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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