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Entry version 108 (12 Aug 2020)
Sequence version 4 (05 Sep 2012)
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Protein

Ciliogenesis and planar polarity effector 1

Gene

Cplane1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in ciliogenesis. Involved in the establishment of cell polarity required for directional cell migration (PubMed:25877302). Proposed to act in association with the CPLANE (ciliogenesis and planar polarity effectors) complex. Involved in recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).1 Publication1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCilium biogenesis/degradation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ciliogenesis and planar polarity effector 1Curated
Alternative name(s):
Protein C5orf42 homolog
Protein JBTS172 Publications
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cplane1Imported
Synonyms:Jbts171 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1920942, Cplane1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei593 – 613HelicalSequence analysisAdd BLAST21
Transmembranei632 – 652HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell projection, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Defects in Jbts17 are the cause of the Hug (Heart under glass) phenotype which is a model of Joubert syndrome. Hug mice die prenatally and show skelatal dysplasia, craniofacial defects, polydactyly, cystic kidney, cerebellar hypoplasia and congenital heart defects of varying degrees. Most severely affected mutants die at mid-gestation with a transparent chest wall due to complete failure to form the rib cage. The phenotype is consistent with the spectrum of MKS-BBS-Joubert syndrome phenotypes.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003443661 – 3214Ciliogenesis and planar polarity effector 1Add BLAST3214

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q8CE72

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q8CE72

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CE72

PRoteomics IDEntifications database

More...
PRIDEi
Q8CE72

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CE72

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CE72

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000039801, Expressed in embryo and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8CE72, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8CE72, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FUZ; INTU and WDPCP; the interactors are proposed to form the core CPLANE (ciliogenesis and planar polarity effectors) complex (PubMed:27158779).

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
216193, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q8CE72, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000106247

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CE72, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8CE72

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRD2, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00800000124150

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_226347_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CE72

KEGG Orthology (KO)

More...
KOi
K22859

Identification of Orthologs from Complete Genome Data

More...
OMAi
CNQKENP

Database of Orthologous Groups

More...
OrthoDBi
55296at2759

TreeFam database of animal gene trees

More...
TreeFami
TF351288

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028236, CPLANE1

The PANTHER Classification System

More...
PANTHERi
PTHR14492, PTHR14492, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15392, Joubert, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q8CE72-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEMRLEVLTS TSIKQKKPWP RVSWLGQENE AVFLLDEKFI NEINLLSGRT
60 70 80 90 100
KKKIPSLQPL LKDVVFLATS TNDVWLSGVL TTGELFLWNK DQDCLKKIHV
110 120 130 140 150
TEKPKEAIKA AVASSSRLYL YVAENGKRIL LITSSGCILL WEYLELKNIL
160 170 180 190 200
SSKSLSLVGQ WSQIVPEEAV SLPSTKDKEA VVAAVFVKNE LLGDCCLCSF
210 220 230 240 250
TFYSGECLKL TFLDIQWYEN IFTSVRSLLF RVHWAQQECP LCSLIPRCAS
260 270 280 290 300
VKSRGALISA FSRDGLALAV TLNQKDPTAT QVLFINTLNF VTLCGGLKGC
310 320 330 340 350
SNKNPVVPAT LTRSYWVGDI SWTHDSLFLT CVLKRGSLVL LTCLGELLTL
360 370 380 390 400
VTFGCSIEFG PAEFIPLHPL ITYRPQQLPF QDSNNCVDSS ASESDPLRQR
410 420 430 440 450
FSIKAHSRLP YLIISDGYMV TTLRFLDNQS PTMLMRSLLL DSTQRLEKAY
460 470 480 490 500
QSMMLSEPKD KGLNFRSLDS LRSSLLKHQG KESSVHCTVP RFLQAEETMK
510 520 530 540 550
LNETTDFQDF EGEETNEVEQ FVNNSFSFCN QKKDLPFDIV KEGRLEFASM
560 570 580 590 600
FDTVHAKDAS KETDRNTAEL HRIQKTLLAA WTIGISKNVT EKKLMLNYTI
610 620 630 640 650
LCITHFFYIL QFIKCPVPKF DLFLNKSLKR NAWVLCVFQL FHQCLSVHYW
660 670 680 690 700
DMRYRQNMGH LIRLTANTVK LLLTQRQEHG SFSERLLACL SLLRTVTVHL
710 720 730 740 750
NGTCSLQPEA VPAAADESRP AELDSLMVPI FQASKENWPW DSSLKIYPQV
760 770 780 790 800
TNLVQKPGHR LIALWRLLYK KTLWYQAQLS QRTPDGDRRL TENIRHEVSV
810 820 830 840 850
VKTLLCHVQT NLQMAGDSLN QALELTPISG EECFLLASYE KSVCLWKKAL
860 870 880 890 900
QETQEKGGRR TCFLQLRYYL SLLYCHLYCY NLNDAQGLCD HLVRELLSRS
910 920 930 940 950
QLPVRESQDC SDCEIAVTGN VHPEAALRVV QCMARFMAAY FTNEPLFILP
960 970 980 990 1000
PHSVSVLPPL HVKTEHSLRL IPLQHSKVAS VIRDQNLSNV WTVEYTLELL
1010 1020 1030 1040 1050
FIGGLIPEAV WMAHKLGDWK TSVSIGVAYQ VFCKHDCNFA RSKKKGMDLP
1060 1070 1080 1090 1100
LNMIPAQIFQ EKLQCFLGQP VSLTKKNEKG SKYKQFTDPI EEEDASLLFG
1110 1120 1130 1140 1150
SVQEVLKASV MADADIVSET LQLLMDSAKD FSKKLWGLVP VDLYLPAPPL
1160 1170 1180 1190 1200
YCPQPAVLSE EHGDNLLLKA EKDNRQKLSG ILQRVLLLFR ASRCSFPVAQ
1210 1220 1230 1240 1250
WYILQLRWAR KVMQKIRVKG SLPSLGSFPE SLLNYCKGGI AFFRPGATGD
1260 1270 1280 1290 1300
HTLDEVSIKA LGCFRELCAL CWMLHVRDKL SYTCRQYQKA RENTKIEKDL
1310 1320 1330 1340 1350
EVGFDSCVVE HCFHALEWAC RMLPFSRFFN MEELIQDIIL SLIGELPPIR
1360 1370 1380 1390 1400
KVAEIFVKAF PNPEAIRVPL REKYHSLQQK LKHGVVKGPQ TEELMSTVMR
1410 1420 1430 1440 1450
HVRKVRVKAL KRVQRNIGAF EMDIWEPDEE DKPAATPAAD RFSLGPSVSS
1460 1470 1480 1490 1500
TLTLDLGSSL LHSDADTFSE TLSLEEKTWI HLYQRHTPSH MELALVGKKP
1510 1520 1530 1540 1550
SDKKKVSNQK ENSQRKEDDE TPGKEALPVI GVWEFERDDD EYISFLELFL
1560 1570 1580 1590 1600
SYILERDLCS SDPGIPFLTS FSGRLREHEL NSLLFDVHTT LKRRQSKTIS
1610 1620 1630 1640 1650
ENVYRAGSCF AVTPESQEPE NLSSLNSVGA RHFESQALSA SALGNQSGST
1660 1670 1680 1690 1700
LENPLQSGST SENPLQSDVM NWERRAGLFG LKQKPMYRVP DDKREKPTVQ
1710 1720 1730 1740 1750
RSSNHSFWVP ESIKPGRHRF RALEGSAGPP REDLPLALQS MFGDAGRLVE
1760 1770 1780 1790 1800
WMIRWSDRRL LCDPGVTPSS CKYSPVIRVK TSTAAILTSL WLLEQPYSAA
1810 1820 1830 1840 1850
YTAKNGIIKV LERHHTEPQV AAERESDVDA DCPAAVAAQE GTECWNRMPA
1860 1870 1880 1890 1900
EAENHDVKDT GDEIAPVTPG SERELVHADG RHSEAGSSTQ DEMDVHISDS
1910 1920 1930 1940 1950
EEGPVESLRG PSAVICRPES QLSSEHSEEE AQCSRKEPRD ASVDTNLTEQ
1960 1970 1980 1990 2000
KGAQISDLKE KSPTVLPLMS NGAQDTSQTP QKTQGNEHRA QLPDASESVR
2010 2020 2030 2040 2050
QMLQDEMFKL VQLQQINFLS LMQIVGPSVA SLPDMHGLLQ QAQSVRFGES
2060 2070 2080 2090 2100
QVSNSTKSDC IEVNSRQRVS ARAQSMGECT REPGKNSPAD HKRISRPDQD
2110 2120 2130 2140 2150
SSGDTQDIPH GSVPLCQLDG QPEVRGQTGA PRSFAPASFP PAPAADSGLQ
2160 2170 2180 2190 2200
LLFTPAAIQK TPQLIPPARA GAPGRGFPLL HFQPKRDFKP LSLPVGRIPQ
2210 2220 2230 2240 2250
VSFRPQAQPK EAWSLSDSCQ PPVSQRTVHT TLPSPSDSSH CNAEAMRKAE
2260 2270 2280 2290 2300
AVLTGIPKHV NMGQYAGQGY LTPQQDSSVF IKPENVFDVK PSPPETALQN
2310 2320 2330 2340 2350
SFGLPLLHLQ FKPPYVFSAP PRAFSRFPSV PGTEGRNQPQ LSLLHPCLPP
2360 2370 2380 2390 2400
ENTYKKPQLI PLENLLAFKR SQQKLAHSVS GQGDAAPHFV GVSMDAAGIT
2410 2420 2430 2440 2450
QGKQRQSRRA KRELQEGRAQ KPRRKPNVSF RPEDSLISND SEVIIEPKEQ
2460 2470 2480 2490 2500
LGHHDSQHLD KFDIPFEMLE DDINTSAGLH FMASVRKKAV GSHDASTNTD
2510 2520 2530 2540 2550
PDKEGPSQKA DSESSKNPQA TAASSGHEPL KVPQLLIPDI YLNVRLPSGI
2560 2570 2580 2590 2600
AEKPLSPSPP HMAGHKYIDV VDIEADDLLG LPACEEPSDE VTKQQSHPPH
2610 2620 2630 2640 2650
APSSAELHCM AASIVDAAPP HTFQSQESAS STRGLISEPA KVTQSCQSGE
2660 2670 2680 2690 2700
SWRKSVIEAK EPEIPSVAPP SDRQQDRDIL EQNFQFKEQS TKLDSVGQSL
2710 2720 2730 2740 2750
LWTLLQNASP ACPTPSPAVC PRPSSPACPP PSPAVCPPPS PAACPTPSPA
2760 2770 2780 2790 2800
AQKFEHLTAK LQEMDEQLVA VQTMAENIEQ DFPASQVLNL HWEKAGLGNH
2810 2820 2830 2840 2850
VGLSSGPDIE KLLASKAISI SEEVSLQTQE DVEEQKDAEE TSETEFSEAE
2860 2870 2880 2890 2900
NHSSQKTYAC PSVGSAACSS VGWNIPSPGL NDSNELLESG SEDQLQVTGL
2910 2920 2930 2940 2950
TDIADIIGDL ITKSGVSSHE LGLTECQARS ISRIQRPPDR GPRRTAEERR
2960 2970 2980 2990 3000
EIKAWMRRKQ KERMSEYLGQ LAERRGRERN PFCPTSSPFY MTSRQIRQRQ
3010 3020 3030 3040 3050
KMKREKDRLQ LSKHYSQRLS QAYSLMNELL SDSAHITAPA ENPLPPGPYR
3060 3070 3080 3090 3100
RQRGSSPKRE NAHGQSLPVN RPGGDRHISR SSHLCKGQPR GSSQLRGSQP
3110 3120 3130 3140 3150
PCQSQKPLRS RGAAGVGPPV QQACREDERE EMVVSPWTLP SEIHRILHGR
3160 3170 3180 3190 3200
PESLLQDMSP ADEEEPEPPL LAGGMDSVSE STGSILSKLD WKAVEDMVAS
3210
VEDKNLSVHW ALDQ
Length:3,214
Mass (Da):358,550
Last modified:September 5, 2012 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB431ABFE11324D32
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BRY0A0A2I3BRY0_MOUSE
Ciliogenesis and planar polarity ef...
Cplane1 2410089E03Rik
31Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH58107 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
The sequence BAE22427 differs from that shown. Contaminating sequence. Intron sequences at both 5' and 3' ends.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1061E → K in BAC26182 (PubMed:16141072).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti253S → P in Hug. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC107747 Genomic DNA No translation available.
AC158971 Genomic DNA No translation available.
AK028897 mRNA Translation: BAC26182.2
AK135113 mRNA Translation: BAE22427.1 Sequence problems.
BC058107 mRNA Translation: AAH58107.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS49578.1

NCBI Reference Sequences

More...
RefSeqi
NP_001156378.1, NM_001162906.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000110617; ENSMUSP00000106247; ENSMUSG00000039801

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
73692

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:73692

UCSC genome browser

More...
UCSCi
uc007ven.2, mouse

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC107747 Genomic DNA No translation available.
AC158971 Genomic DNA No translation available.
AK028897 mRNA Translation: BAC26182.2
AK135113 mRNA Translation: BAE22427.1 Sequence problems.
BC058107 mRNA Translation: AAH58107.1 Different initiation.
CCDSiCCDS49578.1
RefSeqiNP_001156378.1, NM_001162906.1

3D structure databases

SMRiQ8CE72
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi216193, 3 interactors
IntActiQ8CE72, 1 interactor
STRINGi10090.ENSMUSP00000106247

PTM databases

iPTMnetiQ8CE72
PhosphoSitePlusiQ8CE72

Proteomic databases

EPDiQ8CE72
MaxQBiQ8CE72
PaxDbiQ8CE72
PRIDEiQ8CE72

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
51274, 46 antibodies

Genome annotation databases

EnsembliENSMUST00000110617; ENSMUSP00000106247; ENSMUSG00000039801
GeneIDi73692
KEGGimmu:73692
UCSCiuc007ven.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
65250
MGIiMGI:1920942, Cplane1

Phylogenomic databases

eggNOGiENOG502QRD2, Eukaryota
GeneTreeiENSGT00800000124150
HOGENOMiCLU_226347_0_0_1
InParanoidiQ8CE72
KOiK22859
OMAiCNQKENP
OrthoDBi55296at2759
TreeFamiTF351288

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
73692, 3 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Cplane1, mouse

Protein Ontology

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PROi
PR:Q8CE72
RNActiQ8CE72, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000039801, Expressed in embryo and 242 other tissues
ExpressionAtlasiQ8CE72, baseline and differential
GenevisibleiQ8CE72, MM

Family and domain databases

InterProiView protein in InterPro
IPR028236, CPLANE1
PANTHERiPTHR14492, PTHR14492, 1 hit
PfamiView protein in Pfam
PF15392, Joubert, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCPLN1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CE72
Secondary accession number(s): E9QL36, Q3UXY6, Q6PEE0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: September 5, 2012
Last modified: August 12, 2020
This is version 108 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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