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Protein

Tctex1 domain-containing protein 4

Gene

Tctex1d4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Tctex1 domain-containing protein 4
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:3045358 Tctex1d4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003168711 – 219Tctex1 domain-containing protein 4Add BLAST219

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei64PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ8CDY7
PaxDbiQ8CDY7
PRIDEiQ8CDY7

PTM databases

iPTMnetiQ8CDY7
PhosphoSitePlusiQ8CDY7

Expressioni

Gene expression databases

BgeeiENSMUSG00000047671 Expressed in 34 organ(s), highest expression level in olfactory epithelium
CleanExiMM_TCTEX1D4
ExpressionAtlasiQ8CDY7 baseline and differential
GenevisibleiQ8CDY7 MM

Interactioni

Subunit structurei

Interacts with ENG/endoglin, TGFBR2 and TGFBR3.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052243

Structurei

3D structure databases

ProteinModelPortaliQ8CDY7
SMRiQ8CDY7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4108 Eukaryota
ENOG4111RVM LUCA
GeneTreeiENSGT00530000063097
HOGENOMiHOG000154519
HOVERGENiHBG096850
InParanoidiQ8CDY7
OMAiSYRTEPA
OrthoDBiEOG091G0PRF
PhylomeDBiQ8CDY7
TreeFamiTF313904

Family and domain databases

Gene3Di3.30.1140.40, 1 hit
InterProiView protein in InterPro
IPR005334 Tctex
IPR038586 Tctex-1-like_sf
PANTHERiPTHR21255 PTHR21255, 1 hit
PfamiView protein in Pfam
PF03645 Tctex-1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8CDY7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MACRTLPSRR QEEETTKDLA LKLPPGKPGG HLPSIDETRP IGPGPASRRG
60 70 80 90 100
SLPGLHPSFS RRNSLAGPLV GPGGRRPSLG PVPPLGSRVS FSGLPLMLPR
110 120 130 140 150
RMAPSYRLEP APGEHWEAAG AQRALEAALT TQLNGVCYCG SEAGKLVQAL
160 170 180 190 200
CEQIHTRVRE LNLPRYKLVC NVVLGPREGQ GVHVVSRALW DAVHDGLASA
210
TFTNPSLFAV ATVHAVYWE
Length:219
Mass (Da):23,451
Last modified:March 1, 2003 - v1
Checksum:iC1F15926C6CAB4B4
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MQL6A0A0A0MQL6_MOUSE
Tctex1 domain-containing protein 4
Tctex1d4
178Annotation score:
A0A0A0MQF8A0A0A0MQF8_MOUSE
Tctex1 domain-containing protein 4
Tctex1d4
118Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti82V → M in AAI15475 (PubMed:15489334).Curated1
Sequence conflicti109E → D in AAI15475 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029345 mRNA Translation: BAC26409.1
AL671866 Genomic DNA No translation available.
BC115474 mRNA Translation: AAI15475.1
CCDSiCCDS18528.1
RefSeqiNP_778195.1, NM_175030.2
XP_006503160.1, XM_006503097.3
XP_006503161.1, XM_006503098.3
XP_006503162.1, XM_006503099.3
XP_006503163.1, XM_006503100.3
UniGeneiMm.358914

Genome annotation databases

EnsembliENSMUST00000062206; ENSMUSP00000052243; ENSMUSG00000047671
GeneIDi242646
KEGGimmu:242646
UCSCiuc008uia.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK029345 mRNA Translation: BAC26409.1
AL671866 Genomic DNA No translation available.
BC115474 mRNA Translation: AAI15475.1
CCDSiCCDS18528.1
RefSeqiNP_778195.1, NM_175030.2
XP_006503160.1, XM_006503097.3
XP_006503161.1, XM_006503098.3
XP_006503162.1, XM_006503099.3
XP_006503163.1, XM_006503100.3
UniGeneiMm.358914

3D structure databases

ProteinModelPortaliQ8CDY7
SMRiQ8CDY7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052243

PTM databases

iPTMnetiQ8CDY7
PhosphoSitePlusiQ8CDY7

Proteomic databases

MaxQBiQ8CDY7
PaxDbiQ8CDY7
PRIDEiQ8CDY7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062206; ENSMUSP00000052243; ENSMUSG00000047671
GeneIDi242646
KEGGimmu:242646
UCSCiuc008uia.1 mouse

Organism-specific databases

CTDi343521
MGIiMGI:3045358 Tctex1d4

Phylogenomic databases

eggNOGiKOG4108 Eukaryota
ENOG4111RVM LUCA
GeneTreeiENSGT00530000063097
HOGENOMiHOG000154519
HOVERGENiHBG096850
InParanoidiQ8CDY7
OMAiSYRTEPA
OrthoDBiEOG091G0PRF
PhylomeDBiQ8CDY7
TreeFamiTF313904

Miscellaneous databases

PROiPR:Q8CDY7
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047671 Expressed in 34 organ(s), highest expression level in olfactory epithelium
CleanExiMM_TCTEX1D4
ExpressionAtlasiQ8CDY7 baseline and differential
GenevisibleiQ8CDY7 MM

Family and domain databases

Gene3Di3.30.1140.40, 1 hit
InterProiView protein in InterPro
IPR005334 Tctex
IPR038586 Tctex-1-like_sf
PANTHERiPTHR21255 PTHR21255, 1 hit
PfamiView protein in Pfam
PF03645 Tctex-1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTC1D4_MOUSE
AccessioniPrimary (citable) accession number: Q8CDY7
Secondary accession number(s): A2AE79, A2AE80, Q14C28
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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