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Protein

Zinc finger and BTB domain-containing protein 9

Gene

Zbtb9

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri397 – 419C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 9
Gene namesi
Name:Zbtb9
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1918022 Zbtb9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000477241 – 459Zinc finger and BTB domain-containing protein 9Add BLAST459

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki285Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki293Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki368Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiQ8CDC7
PaxDbiQ8CDC7
PeptideAtlasiQ8CDC7
PRIDEiQ8CDC7

PTM databases

PhosphoSitePlusiQ8CDC7

Expressioni

Gene expression databases

BgeeiENSMUSG00000079605
CleanExiMM_ZBTB9
GenevisibleiQ8CDC7 MM

Interactioni

Protein-protein interaction databases

BioGridi243089, 5 interactors
IntActiQ8CDC7, 1 interactor
STRINGi10090.ENSMUSP00000112778

Structurei

3D structure databases

ProteinModelPortaliQ8CDC7
SMRiQ8CDC7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 112BTBPROSITE-ProRule annotationAdd BLAST65

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri397 – 419C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 2; atypicalPROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00760000119063
HOGENOMiHOG000231208
HOVERGENiHBG101113
InParanoidiQ8CDC7
KOiK10496
OMAiEHMKTHA
OrthoDBiEOG091G07XH
PhylomeDBiQ8CDC7

Family and domain databases

InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 2 hits
SUPFAMiSSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CDC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDASTPLPPA SSSPRCNPAP QTIHIEFPHH SSSLLESLNR HRLEGKFCDV
60 70 80 90 100
SLLVQGRELR AHKAVLAAAS PYFHDKLLLG DAPRLTLPNV IEADAFEGLL
110 120 130 140 150
QLIYSGSLHL PLDALPAHLL VASGLQMWQV VDRCSEILRE LETSGGISAG
160 170 180 190 200
GRASSLTLIS TTSSGGWCIR SSPFQNPVRS SASTENSVLP ESPAGGEGSE
210 220 230 240 250
LEGMLQIQVK VEEEEEQGSA APLFQTPQPE RVSGGVSQAC GSHPLPTPAL
260 270 280 290 300
PSKPSEDESS TVDPPAPPVQ ASQILYVNQE NVECKEEIAR GTKEKTKVLS
310 320 330 340 350
GEDSEEKEEL RYLLSSGGGE SSGAGDPSWK PVDLHGNEIL SGDGGPGGTG
360 370 380 390 400
QAMHGPVKLG GTPPADGKCF ACLCGKRFAV KPKRDRHIML TFSLRPFGCG
410 420 430 440 450
ICNKRFKLKH HLTEHMKTHA RALHACPHCG RRFRVQAFFL RHRDLCKGQG

WPTYHWTYK
Length:459
Mass (Da):49,536
Last modified:March 1, 2003 - v1
Checksum:i1984B0D0242F06D1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti251P → T in BAB29365 (PubMed:16141072).Curated1
Sequence conflicti425A → V in BAB29365 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014458 mRNA Translation: BAB29365.1
AK030262 mRNA Translation: BAC26866.1
AK154850 mRNA Translation: BAE32876.1
BC049933 mRNA Translation: AAH49933.1
BC054732 mRNA No translation available.
BC060527 mRNA No translation available.
CCDSiCCDS37520.1
RefSeqiNP_001005916.1, NM_001005916.2
UniGeneiMm.328890

Genome annotation databases

EnsembliENSMUST00000120016; ENSMUSP00000112778; ENSMUSG00000079605
GeneIDi474156
KEGGimmu:474156
UCSCiuc008bfb.1 mouse

Similar proteinsi

Entry informationi

Entry nameiZBTB9_MOUSE
AccessioniPrimary (citable) accession number: Q8CDC7
Secondary accession number(s): Q3U3B2, Q9CYQ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: March 1, 2003
Last modified: November 22, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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