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Protein

Solute carrier family 35 member E1

Gene

Slc35e1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Putative transporter.By similarity

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 35 member E1
Gene namesi
Name:Slc35e1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2142403 Slc35e1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei50 – 70HelicalSequence analysisAdd BLAST21
Transmembranei111 – 131HelicalSequence analysisAdd BLAST21
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei165 – 184HelicalSequence analysisAdd BLAST20
Transmembranei188 – 207HelicalSequence analysisAdd BLAST20
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei252 – 274HelicalSequence analysisAdd BLAST23
Transmembranei282 – 303HelicalSequence analysisAdd BLAST22
Transmembranei312 – 332HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000719421 – 409Solute carrier family 35 member E1Add BLAST409

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei363PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ8CD26
MaxQBiQ8CD26
PaxDbiQ8CD26
PeptideAtlasiQ8CD26
PRIDEiQ8CD26
TopDownProteomicsiQ8CD26

PTM databases

iPTMnetiQ8CD26
PhosphoSitePlusiQ8CD26

Expressioni

Gene expression databases

BgeeiENSMUSG00000019731 Expressed in 291 organ(s), highest expression level in diaphragm
CleanExiMM_SLC35E1
GenevisibleiQ8CD26 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000115754

Structurei

3D structure databases

SMRiQ8CD26
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1441 Eukaryota
ENOG410XP1S LUCA
GeneTreeiENSGT00530000063705
HOGENOMiHOG000241297
HOVERGENiHBG067079
InParanoidiQ8CD26
KOiK15283
OMAiGFPYPVT
OrthoDBiEOG091G0C5E
PhylomeDBiQ8CD26
TreeFamiTF324822

Family and domain databases

InterProiView protein in InterPro
IPR004853 Sugar_P_trans_dom
PfamiView protein in Pfam
PF03151 TPT, 1 hit

Sequencei

Sequence statusi: Complete.

Q8CD26-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAATAGPG AGAGVPGAGG GGGAREGARV AVLCLLWYAL SAGGNVVNKV
60 70 80 90 100
ILSAFPFPVT VSLCHILALC AGLPPLLRAW RVPPAPPVSG PGPGPHPASG
110 120 130 140 150
PLLPPRFYPR YVLPLAFGKY FASVSAHVSI WKVPVSYAHT VKATMPIWVV
160 170 180 190 200
LLSRIIMKEK QSTKVYLSLV PIISGVLLAT VTELSFDVWG LVSALAATLC
210 220 230 240 250
FSLQNIFSKK VLRDSRIHHL RLLNILGCHA VFFMIPTWVL VDLSTFLVSS
260 270 280 290 300
DLAYVSQWPW TLLLLAVSGF CNFAQNVIAF SILNLISPLS YSVANATKRI
310 320 330 340 350
MVITVSLIML RNPVTSTNVL GMMTAILGVF LYNKTKYDAN QQARRHLLPI
360 370 380 390 400
STSDLSSREH LRSPVEKPHN GALFPQQGDF QYRNILLTDH FQYSRQGHPN

SYALSRHDV
Length:409
Mass (Da):44,325
Last modified:February 26, 2008 - v2
Checksum:i27F0F7297275D0E5
GO

Sequence cautioni

The sequence BAC27470 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC172623 Genomic DNA No translation available.
AK031600 mRNA Translation: BAC27470.1 Different initiation.
CCDSiCCDS22415.2
RefSeqiNP_808434.2, NM_177766.3
UniGeneiMm.291461

Genome annotation databases

EnsembliENSMUST00000152080; ENSMUSP00000115754; ENSMUSG00000019731
GeneIDi270066
KEGGimmu:270066
UCSCiuc009mgd.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC172623 Genomic DNA No translation available.
AK031600 mRNA Translation: BAC27470.1 Different initiation.
CCDSiCCDS22415.2
RefSeqiNP_808434.2, NM_177766.3
UniGeneiMm.291461

3D structure databases

SMRiQ8CD26
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000115754

PTM databases

iPTMnetiQ8CD26
PhosphoSitePlusiQ8CD26

Proteomic databases

EPDiQ8CD26
MaxQBiQ8CD26
PaxDbiQ8CD26
PeptideAtlasiQ8CD26
PRIDEiQ8CD26
TopDownProteomicsiQ8CD26

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000152080; ENSMUSP00000115754; ENSMUSG00000019731
GeneIDi270066
KEGGimmu:270066
UCSCiuc009mgd.2 mouse

Organism-specific databases

CTDi79939
MGIiMGI:2142403 Slc35e1

Phylogenomic databases

eggNOGiKOG1441 Eukaryota
ENOG410XP1S LUCA
GeneTreeiENSGT00530000063705
HOGENOMiHOG000241297
HOVERGENiHBG067079
InParanoidiQ8CD26
KOiK15283
OMAiGFPYPVT
OrthoDBiEOG091G0C5E
PhylomeDBiQ8CD26
TreeFamiTF324822

Miscellaneous databases

ChiTaRSiSlc35e1 mouse
PROiPR:Q8CD26
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000019731 Expressed in 291 organ(s), highest expression level in diaphragm
CleanExiMM_SLC35E1
GenevisibleiQ8CD26 MM

Family and domain databases

InterProiView protein in InterPro
IPR004853 Sugar_P_trans_dom
PfamiView protein in Pfam
PF03151 TPT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiS35E1_MOUSE
AccessioniPrimary (citable) accession number: Q8CD26
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: February 26, 2008
Last modified: November 7, 2018
This is version 105 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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