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Protein

Transmembrane protein FAM155A

Gene

Fam155a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • calcium ion import across plasma membrane Source: GO_Central

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein FAM155A
Gene namesi
Name:Fam155a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2142765 Fam155a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Transmembranei426 – 446HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003393741 – 467Transmembrane protein FAM155AAdd BLAST467

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi160N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi226N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi254N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi462N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8CCS2
PRIDEiQ8CCS2

PTM databases

PhosphoSitePlusiQ8CCS2

Expressioni

Gene expression databases

BgeeiENSMUSG00000079157 Expressed in 129 organ(s), highest expression level in pineal body
ExpressionAtlasiQ8CCS2 baseline and differential
GenevisibleiQ8CCS2 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106596

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi74 – 110Poly-GlnAdd BLAST37
Compositional biasi147 – 151Poly-Gly5

Sequence similaritiesi

Belongs to the FAM155 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IKAJ Eukaryota
ENOG410ZYWZ LUCA
GeneTreeiENSGT00390000006985
HOGENOMiHOG000090197
HOVERGENiHBG107868
InParanoidiQ8CCS2
OMAiSPDNLNC
OrthoDBiEOG091G07ZK
PhylomeDBiQ8CCS2
TreeFamiTF331752

Family and domain databases

InterProiView protein in InterPro
IPR029604 FAM155
PANTHERiPTHR15819:SF9 PTHR15819:SF9, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CCS2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTRGAWMCRQ YDDGLKIWLA APRENEKPFI DSERAQKWRL SLASLLFFTV
60 70 80 90 100
LLSDHLWFCA EAKLTRTRDK EHHQQQQQQQ QQQQQQQQQQ QQQQQRQQQR
110 120 130 140 150
QRQQQRQRQQ EPSWPALLAS MGESSPAAQA HRLLSASSSP TLPPSPGGGG
160 170 180 190 200
GSKGNRGKNN RSRALFLGNS AKPVWRLETC YPQGASSGQC FTVESADAVC
210 220 230 240 250
ARNWSRGAAA GEEQSSRGSR PTPLWNLSDF YLSFCNSYTL WELFSGLSSP
260 270 280 290 300
STLNCSLDVV LTEGGEMTTC RQCIEAYQDY DHHAQEKYEE FESVLHKYLQ
310 320 330 340 350
SDEYSVKSCP EDCKIVYKAW LCSQYFEVTQ FNCRKTIPCK QYCLEVQTRC
360 370 380 390 400
PFILPDNDEV IYGGLSSFIC TGLYETFLTN DEPECCDIRS EEQTAPRPKG
410 420 430 440 450
TVDRRDSCPR TSLTVSSATR LCPGRLKLCV LVLILLHTVL TASAAQNSTG
460
LGLGGLPTLE DNSTRED
Length:467
Mass (Da):52,739
Last modified:March 1, 2003 - v1
Checksum:i3DFC917DC35E2289
GO
Isoform 2 (identifier: Q8CCS2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     373-378: LYETFL → EGEVYL
     379-467: Missing.

Note: No experimental confirmation available.
Show »
Length:378
Mass (Da):43,158
Checksum:i84F2BA8BE4B4AF68
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A140LIV2A0A140LIV2_MOUSE
Transmembrane protein FAM155A
Fam155a
21Annotation score:

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_034162373 – 378LYETFL → EGEVYL in isoform 2. 1 Publication6
Alternative sequenceiVSP_034163379 – 467Missing in isoform 2. 1 PublicationAdd BLAST89

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032202 mRNA Translation: BAC27755.1
BC117535 mRNA Translation: AAI17536.1
CCDSiCCDS40216.1 [Q8CCS2-1]
CCDS85497.1 [Q8CCS2-2]
RefSeqiNP_001334056.1, NM_001347127.1 [Q8CCS2-2]
NP_775622.1, NM_173446.2 [Q8CCS2-1]
UniGeneiMm.268163
Mm.435277

Genome annotation databases

EnsembliENSMUST00000110969; ENSMUSP00000106596; ENSMUSG00000079157 [Q8CCS2-1]
ENSMUST00000208933; ENSMUSP00000146609; ENSMUSG00000079157 [Q8CCS2-2]
GeneIDi270028
KEGGimmu:270028
UCSCiuc009kuj.1 mouse [Q8CCS2-1]
uc009kuk.1 mouse [Q8CCS2-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032202 mRNA Translation: BAC27755.1
BC117535 mRNA Translation: AAI17536.1
CCDSiCCDS40216.1 [Q8CCS2-1]
CCDS85497.1 [Q8CCS2-2]
RefSeqiNP_001334056.1, NM_001347127.1 [Q8CCS2-2]
NP_775622.1, NM_173446.2 [Q8CCS2-1]
UniGeneiMm.268163
Mm.435277

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106596

PTM databases

PhosphoSitePlusiQ8CCS2

Proteomic databases

PaxDbiQ8CCS2
PRIDEiQ8CCS2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000110969; ENSMUSP00000106596; ENSMUSG00000079157 [Q8CCS2-1]
ENSMUST00000208933; ENSMUSP00000146609; ENSMUSG00000079157 [Q8CCS2-2]
GeneIDi270028
KEGGimmu:270028
UCSCiuc009kuj.1 mouse [Q8CCS2-1]
uc009kuk.1 mouse [Q8CCS2-2]

Organism-specific databases

CTDi728215
MGIiMGI:2142765 Fam155a

Phylogenomic databases

eggNOGiENOG410IKAJ Eukaryota
ENOG410ZYWZ LUCA
GeneTreeiENSGT00390000006985
HOGENOMiHOG000090197
HOVERGENiHBG107868
InParanoidiQ8CCS2
OMAiSPDNLNC
OrthoDBiEOG091G07ZK
PhylomeDBiQ8CCS2
TreeFamiTF331752

Miscellaneous databases

ChiTaRSiFam155a mouse
PROiPR:Q8CCS2
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000079157 Expressed in 129 organ(s), highest expression level in pineal body
ExpressionAtlasiQ8CCS2 baseline and differential
GenevisibleiQ8CCS2 MM

Family and domain databases

InterProiView protein in InterPro
IPR029604 FAM155
PANTHERiPTHR15819:SF9 PTHR15819:SF9, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF155A_MOUSE
AccessioniPrimary (citable) accession number: Q8CCS2
Secondary accession number(s): Q149R3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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