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Protein

Methyltransferase-like protein 24

Gene

Mettl24

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Methyltransferase-like protein 24 (EC:2.1.1.-)
Gene namesi
Name:Mettl24
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:3045338 Mettl24

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 38Sequence analysisAdd BLAST38
ChainiPRO_000034374439 – 363Methyltransferase-like protein 24Add BLAST325

Proteomic databases

PaxDbiQ8CCB5
PRIDEiQ8CCB5

PTM databases

iPTMnetiQ8CCB5
PhosphoSitePlusiQ8CCB5

Expressioni

Gene expression databases

BgeeiENSMUSG00000045555 Expressed in 75 organ(s), highest expression level in indifferent gonad
GenevisibleiQ8CCB5 MM

Structurei

3D structure databases

ProteinModelPortaliQ8CCB5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IHCM Eukaryota
ENOG410Y3P7 LUCA
GeneTreeiENSGT00390000002881
HOGENOMiHOG000111577
HOVERGENiHBG107658
InParanoidiQ8CCB5
OMAiPRWHIDL
OrthoDBiEOG091G08NE
PhylomeDBiQ8CCB5
TreeFamiTF330614

Family and domain databases

InterProiView protein in InterPro
IPR025714 Methyltranfer_dom
IPR026913 METTL24
PANTHERiPTHR32026 PTHR32026, 1 hit
PfamiView protein in Pfam
PF13383 Methyltransf_22, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8CCB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATVKPPGRG CGALPRWLLG AALLLGLRLC MELRHAGSGP PGRGDSPGPP
60 70 80 90 100
RTHLLSAPGS PRGARRRQVT YVRSGRRVLP RGGGSTTSPE PSCCAQGGLL
110 120 130 140 150
RRKGSRWHIE LQPWAGPSRS LDEEASRFLS YISTTQIACD HMGTDSLATD
160 170 180 190 200
SSPAPKPWLV CLDDRFGLAH QIRSKRCRLY SLGLGSDDTH FEVSMANGGC
210 220 230 240 250
EVHRFDPSVK SAHVLERQGL WHHRLSIDWR DPHPAVAAQK PHGNTRKLGS
260 270 280 290 300
ILNEFGHHKI DVLKADLESA EWKVLENLIL EDVLEQIGQL VFEIHLHWPG
310 320 330 340 350
FEVSGSESGV VRFWYSLLKE LERKHFRLFH TYKDLTKPQL FLKKDLFNAS
360
SCYTLSWVNT KWR
Length:363
Mass (Da):40,631
Last modified:March 1, 2003 - v1
Checksum:i0FDFED6C04E9DB38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033488 mRNA Translation: BAC28315.1
CH466540 Genomic DNA Translation: EDL04960.1
BC147316 mRNA Translation: AAI47317.1
BC147317 mRNA Translation: AAI47318.1
CCDSiCCDS23799.1
RefSeqiNP_808461.1, NM_177793.3
UniGeneiMm.80407

Genome annotation databases

EnsembliENSMUST00000058747; ENSMUSP00000049997; ENSMUSG00000045555
GeneIDi327747
KEGGimmu:327747
UCSCiuc007exd.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033488 mRNA Translation: BAC28315.1
CH466540 Genomic DNA Translation: EDL04960.1
BC147316 mRNA Translation: AAI47317.1
BC147317 mRNA Translation: AAI47318.1
CCDSiCCDS23799.1
RefSeqiNP_808461.1, NM_177793.3
UniGeneiMm.80407

3D structure databases

ProteinModelPortaliQ8CCB5
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ8CCB5
PhosphoSitePlusiQ8CCB5

Proteomic databases

PaxDbiQ8CCB5
PRIDEiQ8CCB5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000058747; ENSMUSP00000049997; ENSMUSG00000045555
GeneIDi327747
KEGGimmu:327747
UCSCiuc007exd.1 mouse

Organism-specific databases

CTDi728464
MGIiMGI:3045338 Mettl24

Phylogenomic databases

eggNOGiENOG410IHCM Eukaryota
ENOG410Y3P7 LUCA
GeneTreeiENSGT00390000002881
HOGENOMiHOG000111577
HOVERGENiHBG107658
InParanoidiQ8CCB5
OMAiPRWHIDL
OrthoDBiEOG091G08NE
PhylomeDBiQ8CCB5
TreeFamiTF330614

Miscellaneous databases

PROiPR:Q8CCB5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000045555 Expressed in 75 organ(s), highest expression level in indifferent gonad
GenevisibleiQ8CCB5 MM

Family and domain databases

InterProiView protein in InterPro
IPR025714 Methyltranfer_dom
IPR026913 METTL24
PANTHERiPTHR32026 PTHR32026, 1 hit
PfamiView protein in Pfam
PF13383 Methyltransf_22, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMET24_MOUSE
AccessioniPrimary (citable) accession number: Q8CCB5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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