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Protein

DCN1-like protein 4

Gene

Dcun1d4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • cullin family protein binding Source: GO_Central
  • ubiquitin conjugating enzyme binding Source: GO_Central
  • ubiquitin-like protein binding Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-8951664 Neddylation

Names & Taxonomyi

Protein namesi
Recommended name:
DCN1-like protein 4
Alternative name(s):
DCUN1 domain-containing protein 4
Defective in cullin neddylation protein 1-like protein 4
Gene namesi
Name:Dcun1d4
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2140972 Dcun1d4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001295041 – 292DCN1-like protein 4Add BLAST292

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki95Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQBiQ8CCA0
PaxDbiQ8CCA0
PRIDEiQ8CCA0

PTM databases

iPTMnetiQ8CCA0
PhosphoSitePlusiQ8CCA0

Expressioni

Gene expression databases

BgeeiENSMUSG00000051674 Expressed in 251 organ(s), highest expression level in testis
ExpressionAtlasiQ8CCA0 baseline and differential
GenevisibleiQ8CCA0 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084427

Structurei

3D structure databases

ProteinModelPortaliQ8CCA0
SMRiQ8CCA0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini102 – 287DCUN1PROSITE-ProRule annotationAdd BLAST186

Phylogenomic databases

eggNOGiKOG3077 Eukaryota
ENOG410XTIJ LUCA
GeneTreeiENSGT00550000074529
HOGENOMiHOG000241761
HOVERGENiHBG106637
InParanoidiQ8CCA0
KOiK17824
OMAiEPTNFKL
PhylomeDBiQ8CCA0
TreeFamiTF354270

Family and domain databases

InterProiView protein in InterPro
IPR014764 DCN-prot
IPR005176 PONY_dom
PANTHERiPTHR12281 PTHR12281, 1 hit
PfamiView protein in Pfam
PF03556 Cullin_binding, 1 hit
PROSITEiView protein in PROSITE
PS51229 DCUN1, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q8CCA0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHSDAAAVNF QLNSHLSTLA SIHKIYHTLN KLNLTEDVGQ DDHQTGSLRS
60 70 80 90 100
CSSSDCFSKV MPPRKKRRPA SGDDLSAKKS RHDSMYRKYE STRIKTEEEA
110 120 130 140 150
FSSKRCLEWF YEYAGTEDAV GPEGMEKFCE DIGVEPENVV MLVLAWKLDA
160 170 180 190 200
QNMGYFTLQE WLKGMTSLQC DTTEKLRTTL DYLRSLLNDT TNFKLIYRYA
210 220 230 240 250
FDFAREKDQR SLDINTAKCM LGLLLGKIWP LFPVFHQFLE QSKYKVINKD
260 270 280 290
QWCNVLEFSR TISLDLSNYD EDGAWPVLLD EFVEWYKDKQ MS
Length:292
Mass (Da):33,939
Last modified:March 1, 2003 - v1
Checksum:iA599872179813601
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8C5X2Q8C5X2_MOUSE
DCN1-like protein
Dcun1d4 AI836376, mCG_126930
306Annotation score:
B7ZMU0B7ZMU0_MOUSE
DCN1-like protein
Dcun1d4
257Annotation score:
D3Z4A7D3Z4A7_MOUSE
DCN1-like protein
Dcun1d4
101Annotation score:
D3Z7G2D3Z7G2_MOUSE
DCN1-like protein
Dcun1d4
106Annotation score:
D3Z664D3Z664_MOUSE
DCN1-like protein
Dcun1d4
46Annotation score:
F7A063F7A063_MOUSE
DCN1-like protein
Dcun1d4
31Annotation score:
D6RHK6D6RHK6_MOUSE
DCN1-like protein
Dcun1d4
85Annotation score:
D6RJL1D6RJL1_MOUSE
DCN1-like protein
Dcun1d4
109Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033559 mRNA Translation: BAC28359.1
BC108346 mRNA Translation: AAI08347.1
BC137627 mRNA Translation: AAI37628.1
BC137628 mRNA Translation: AAI37629.1
CCDSiCCDS19342.1
RefSeqiNP_001177662.1, NM_001190733.1
NP_001177663.1, NM_001190734.1
NP_849227.1, NM_178896.5
UniGeneiMm.220312

Genome annotation databases

EnsembliENSMUST00000063882; ENSMUSP00000067616; ENSMUSG00000051674
GeneIDi100737
KEGGimmu:100737
UCSCiuc008xsz.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK033559 mRNA Translation: BAC28359.1
BC108346 mRNA Translation: AAI08347.1
BC137627 mRNA Translation: AAI37628.1
BC137628 mRNA Translation: AAI37629.1
CCDSiCCDS19342.1
RefSeqiNP_001177662.1, NM_001190733.1
NP_001177663.1, NM_001190734.1
NP_849227.1, NM_178896.5
UniGeneiMm.220312

3D structure databases

ProteinModelPortaliQ8CCA0
SMRiQ8CCA0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000084427

PTM databases

iPTMnetiQ8CCA0
PhosphoSitePlusiQ8CCA0

Proteomic databases

MaxQBiQ8CCA0
PaxDbiQ8CCA0
PRIDEiQ8CCA0

Protocols and materials databases

DNASUi100737
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000063882; ENSMUSP00000067616; ENSMUSG00000051674
GeneIDi100737
KEGGimmu:100737
UCSCiuc008xsz.2 mouse

Organism-specific databases

CTDi23142
MGIiMGI:2140972 Dcun1d4

Phylogenomic databases

eggNOGiKOG3077 Eukaryota
ENOG410XTIJ LUCA
GeneTreeiENSGT00550000074529
HOGENOMiHOG000241761
HOVERGENiHBG106637
InParanoidiQ8CCA0
KOiK17824
OMAiEPTNFKL
PhylomeDBiQ8CCA0
TreeFamiTF354270

Enzyme and pathway databases

ReactomeiR-MMU-8951664 Neddylation

Miscellaneous databases

PROiPR:Q8CCA0
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000051674 Expressed in 251 organ(s), highest expression level in testis
ExpressionAtlasiQ8CCA0 baseline and differential
GenevisibleiQ8CCA0 MM

Family and domain databases

InterProiView protein in InterPro
IPR014764 DCN-prot
IPR005176 PONY_dom
PANTHERiPTHR12281 PTHR12281, 1 hit
PfamiView protein in Pfam
PF03556 Cullin_binding, 1 hit
PROSITEiView protein in PROSITE
PS51229 DCUN1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiDCNL4_MOUSE
AccessioniPrimary (citable) accession number: Q8CCA0
Secondary accession number(s): Q2YDW5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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