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Entry version 149 (02 Jun 2021)
Sequence version 2 (07 Jun 2004)
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Protein

Synaptopodin

Gene

Synpo

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity.

1 Publication

Miscellaneous

Synpo deficient mice develop normally, but they lack the spine apparatuses. Adult mice have an impairment of spatial learning in the radial arm maze test.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin binding Source: MGI

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Synaptopodin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Synpo
Synonyms:Kiaa1029
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1099446, Synpo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction, Cell projection, Cytoplasm, Cytoskeleton, Synapse, Tight junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001876711 – 929SynaptopodinAdd BLAST929

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei134PhosphoserineCombined sources1
Modified residuei202PhosphoserineCombined sources1
Modified residuei222PhosphoserineCombined sources1
Modified residuei258PhosphoserineCombined sources1
Modified residuei488PhosphoserineCombined sources1
Modified residuei512PhosphoserineBy similarity1
Modified residuei547PhosphothreonineBy similarity1
Modified residuei567PhosphoserineBy similarity1
Modified residuei672PhosphoserineCombined sources1
Modified residuei689PhosphoserineCombined sources1
Modified residuei740PhosphoserineCombined sources1
Modified residuei744PhosphoserineCombined sources1
Modified residuei765PhosphoserineBy similarity1
Modified residuei769PhosphothreonineCombined sources1
Modified residuei833PhosphoserineCombined sources1
Modified residuei848Omega-N-methylarginineCombined sources1
Modified residuei854PhosphoserineBy similarity1
Isoform 2 (identifier: Q8CC35-2)
Modified residuei690PhosphoserineCombined sources1
Modified residuei786Omega-N-methylarginineCombined sources1
Modified residuei789PhosphoserineCombined sources1
Modified residuei800Omega-N-methylarginineCombined sources1
Modified residuei803PhosphoserineCombined sources1
Modified residuei814Omega-N-methylarginineCombined sources1
Modified residuei819PhosphoserineCombined sources1
Modified residuei824PhosphoserineCombined sources1
Modified residuei852PhosphoserineCombined sources1
Modified residuei869PhosphoserineBy similarity1
Modified residuei892PhosphoserineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylated.1 Publication

Keywords - PTMi

Glycoprotein, Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q8CC35

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8CC35

PeptideAtlas

More...
PeptideAtlasi
Q8CC35

PRoteomics IDEntifications database

More...
PRIDEi
Q8CC35

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
254716 [Q8CC35-1]
254717 [Q8CC35-2]
254718 [Q8CC35-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8CC35

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8CC35

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in brain, namely in the olfactory bulb, cerebral cortex, striatum, and hippocampus, but not in the cerebellum. Also expressed in the podocytes of kidney glomeruli. In the hippocampus, mainly expressed in the principal cell layer of the dentate gyrus and Ammon's horn.3 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000043079, Expressed in ascending aorta and 327 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8CC35, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8CC35, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with BAIAP1.

Interacts with actin.

Interacts (via PPxY motifs) with WWC1 (via WW domains) (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q8CC35

Protein interaction database and analysis system

More...
IntActi
Q8CC35, 7 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000095174

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8CC35, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni54 – 77DisorderedSequence analysisAdd BLAST24
Regioni111 – 243DisorderedSequence analysisAdd BLAST133
Regioni280 – 382DisorderedSequence analysisAdd BLAST103
Regioni395 – 416DisorderedSequence analysisAdd BLAST22
Regioni497 – 520DisorderedSequence analysisAdd BLAST24
Regioni539 – 595DisorderedSequence analysisAdd BLAST57
Regioni688 – 714DisorderedSequence analysisAdd BLAST27
Regioni805 – 912DisorderedSequence analysisAdd BLAST108

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi549 – 552PPxY motif4
Motifi568 – 571PPxY motif4

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi148 – 173Polar residuesSequence analysisAdd BLAST26
Compositional biasi180 – 198Polar residuesSequence analysisAdd BLAST19
Compositional biasi213 – 227Pro residuesSequence analysisAdd BLAST15
Compositional biasi280 – 296Polar residuesSequence analysisAdd BLAST17
Compositional biasi304 – 363Polar residuesSequence analysisAdd BLAST60
Compositional biasi396 – 416Polar residuesSequence analysisAdd BLAST21
Compositional biasi550 – 579Polar residuesSequence analysisAdd BLAST30
Compositional biasi812 – 833Polar residuesSequence analysisAdd BLAST22
Compositional biasi866 – 894Polar residuesSequence analysisAdd BLAST29

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the synaptopodin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R7RM, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183054

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013103_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8CC35

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8CC35

TreeFam database of animal gene trees

More...
TreeFami
TF330867

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028753, Synpo

The PANTHER Classification System

More...
PANTHERi
PTHR24217:SF13, PTHR24217:SF13, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8CC35-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLGAHFPPPP LGASEGRAAP CTFQIPDGSY RCLALEAEES SSEDGLQGEV
60 70 80 90 100
RLVDLEEEGT SQSRANHGTP PLSRAPAIIQ PSSCHREARG GFQRSDRPSH
110 120 130 140 150
DWDVVQARKV MTASGSSSPV PRVAQKPALG RSTSFTENDL KEAKARSQQI
160 170 180 190 200
AAQLTTPPSS NSRGVQLFNR RRQRVNEFTL ESRGQRSPKL NQEALQTGRP
210 220 230 240 250
LSPIGHAPGP SVKPTSPSKP GSPKHPSPQS PSRGVAGHIM EGYSEEASLL
260 270 280 290 300
RHLEKVASEE EEVPLVVYLK ENAALLTANG LHLSQSRETQ QSSPNPPDTE
310 320 330 340 350
VPSPAADINQ NPSSPNATLT TLASSSHHSQ PTADINQNPP AAITPVPQNS
360 370 380 390 400
SQAQCSPNGT LDSKPGTLCA DDGQSPVPAE EVRSSILLID KVSAPPSAAS
410 420 430 440 450
TFSREATPLS SSGPPAADLM SSSLLIDMQP STLVAPAEQE VPGHVAVTTP
460 470 480 490 500
TKVYSEVHLT LAKPASVVNR TARPFGIQSP GTSQIEQSPM MGRRQFGEKA
510 520 530 540 550
WAPPASSMAD RSPQPQRHIM SRSPMVERRL LGQRSPVLER RPLGNFTPPP
560 570 580 590 600
TYAETLSTAP VASRVRSPPS YSTLYPSSDP KPSHLKGQVA PANKTGILEE
610 620 630 640 650
SMARRGSRKS MFTFVEKPKV TPNPDLLDLV QTADEKRRQR DHGEVGMEEE
660 670 680 690 700
PFALGAEASN FQQEPIARDR ASPAAAEEAV PEWASCLKSP RIQAKPKPKP
710 720 730 740 750
NQNLSEASGK GAELYARRQS RMEKYVIESS GHAELARCPS PTMSLPSSWK
760 770 780 790 800
YTTNAPGGFR VASLSPARTP PASLYHGYLP ENGVLRPEPT KQQPYQMRPS
810 820 830 840 850
LYALSPVKEP AKASSRATSS RTPSRTVSPR AASPAKPSSL DLVPNLPRAG
860 870 880 890 900
LPPSPALPRP SRSSPGLYTA PVQDSLQPTA VSPTYSSDIS PVSPSRAWSP
910 920
RAKQAPRPSF STRNAGIEAQ VWKPSFCFK
Length:929
Mass (Da):99,552
Last modified:June 7, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i979CFEE4F9E061A2
GO
Isoform 2 (identifier: Q8CC35-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-239: Missing.
     921-929: VWKPSFCFK → DRPESLPTSP...SLPTEASCTT

Show »
Length:901
Mass (Da):96,250
Checksum:i14EC69FE4E4889D6
GO
Isoform 3 (identifier: Q8CC35-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-239: Missing.

Show »
Length:690
Mass (Da):74,017
Checksum:i548D75B2AF5BBB62
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q3E2E9Q3E2_MOUSE
Synaptopodin
Synpo
1,100Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E0CYK1E0CYK1_MOUSE
Synaptopodin
Synpo
15Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC28546 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC98077 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti189K → M (Ref. 2) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0104781 – 239Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST239
Alternative sequenceiVSP_010479921 – 929VWKPSFCFK → DRPESLPTSPPWTPAASRPP SSLDGWVSPGPWEPGRGSSM SSPPPLPPPPPMSPSWSERS VSPLRSETEARPPSRQLQAL LARNIINAARRKSASPRPAP AETLRPFSPPQGPPPPPARM RSPQPASPARNFRGAAFSPI PRSPLPIGPSSCASPRSPQA APSRPFPYRRSPTDSDVSLD SEDSGLKSPGILGYNICPRG WNGSLRLKRGSLPTEASCTT in isoform 2. 1 Publication9

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK129267 mRNA Translation: BAC98077.1 Different initiation.
CF539371 mRNA No translation available.
AJ278123 mRNA Translation: CAC34581.1
AK034012 mRNA Translation: BAC28546.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS37833.1 [Q8CC35-2]
CCDS50298.1 [Q8CC35-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000097566; ENSMUSP00000095174; ENSMUSG00000043079 [Q8CC35-2]
ENSMUST00000115318; ENSMUSP00000110973; ENSMUSG00000043079 [Q8CC35-3]
ENSMUST00000130044; ENSMUSP00000121756; ENSMUSG00000043079 [Q8CC35-2]
ENSMUST00000143275; ENSMUSP00000125272; ENSMUSG00000043079 [Q8CC35-1]
ENSMUST00000155195; ENSMUSP00000117897; ENSMUSG00000043079 [Q8CC35-3]

UCSC genome browser

More...
UCSCi
uc008far.2, mouse [Q8CC35-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129267 mRNA Translation: BAC98077.1 Different initiation.
CF539371 mRNA No translation available.
AJ278123 mRNA Translation: CAC34581.1
AK034012 mRNA Translation: BAC28546.1 Different initiation.
CCDSiCCDS37833.1 [Q8CC35-2]
CCDS50298.1 [Q8CC35-3]

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

CORUMiQ8CC35
IntActiQ8CC35, 7 interactors
STRINGi10090.ENSMUSP00000095174

PTM databases

iPTMnetiQ8CC35
PhosphoSitePlusiQ8CC35

Proteomic databases

jPOSTiQ8CC35
PaxDbiQ8CC35
PeptideAtlasiQ8CC35
PRIDEiQ8CC35
ProteomicsDBi254716 [Q8CC35-1]
254717 [Q8CC35-2]
254718 [Q8CC35-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
16210, 300 antibodies

Genome annotation databases

EnsembliENSMUST00000097566; ENSMUSP00000095174; ENSMUSG00000043079 [Q8CC35-2]
ENSMUST00000115318; ENSMUSP00000110973; ENSMUSG00000043079 [Q8CC35-3]
ENSMUST00000130044; ENSMUSP00000121756; ENSMUSG00000043079 [Q8CC35-2]
ENSMUST00000143275; ENSMUSP00000125272; ENSMUSG00000043079 [Q8CC35-1]
ENSMUST00000155195; ENSMUSP00000117897; ENSMUSG00000043079 [Q8CC35-3]
UCSCiuc008far.2, mouse [Q8CC35-1]

Organism-specific databases

MGIiMGI:1099446, Synpo

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiENOG502R7RM, Eukaryota
GeneTreeiENSGT00950000183054
HOGENOMiCLU_013103_0_0_1
InParanoidiQ8CC35
PhylomeDBiQ8CC35
TreeFamiTF330867

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Synpo, mouse

Protein Ontology

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PROi
PR:Q8CC35
RNActiQ8CC35, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000043079, Expressed in ascending aorta and 327 other tissues
ExpressionAtlasiQ8CC35, baseline and differential
GenevisibleiQ8CC35, MM

Family and domain databases

InterProiView protein in InterPro
IPR028753, Synpo
PANTHERiPTHR24217:SF13, PTHR24217:SF13, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSYNPO_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8CC35
Secondary accession number(s): Q99JI0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: June 7, 2004
Last modified: June 2, 2021
This is version 149 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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