UniProtKB - Q8CBB7 (Q8CBB7_MOUSE)
Protein
AP-1 complex subunit gamma
Gene
Ap1g1
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- GTP-dependent protein binding Source: Ensembl
- kinesin binding Source: Ensembl
- Rab GTPase binding Source: Ensembl
GO - Biological processi
- endosome to melanosome transport Source: Ensembl
- Golgi to lysosome transport Source: Ensembl
- intracellular protein transport Source: UniProtKB-UniRule
- positive regulation of natural killer cell degranulation Source: Ensembl
Keywordsi
Biological process | Protein transportUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: AP-1 complex subunit gammaUniRule annotation |
Gene namesi | Name:Ap1g1Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:101919, Ap1g1 |
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Endosome
- recycling endosome Source: Ensembl
Golgi apparatus
- AP-1 adaptor complex Source: InterPro
Keywords - Cellular componenti
Cytoplasmic vesicleUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000031731, Expressed in forelimb bud and 298 other tissues |
ExpressionAtlasi | Q8CBB7, baseline and differential |
Interactioni
GO - Molecular functioni
- GTP-dependent protein binding Source: Ensembl
- kinesin binding Source: Ensembl
- Rab GTPase binding Source: Ensembl
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 705 – 820 | GAEInterPro annotationAdd BLAST | 116 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 596 – 629 | DisorderedSequence analysisAdd BLAST | 34 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 596 – 610 | PolarSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00950000182838 |
OMAi | ATWVIGE |
OrthoDBi | 250202at2759 |
TreeFami | TF300367 |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR017107, AP1_complex_gsu IPR011989, ARM-like IPR016024, ARM-type_fold IPR002553, Clathrin/coatomer_adapt-like_N IPR008152, Clathrin_a/b/g-adaptin_app_Ig IPR013041, Clathrin_app_Ig-like_sf IPR008153, GAE_dom |
Pfami | View protein in Pfam PF01602, Adaptin_N, 1 hit PF02883, Alpha_adaptinC2, 1 hit |
PIRSFi | PIRSF037094, AP1_complex_gamma, 1 hit |
SMARTi | View protein in SMART SM00809, Alpha_adaptinC2, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit SSF49348, SSF49348, 1 hit |
PROSITEi | View protein in PROSITE PS50180, GAE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q8CBB7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPAPIRLREL IRTIRTARTQ AEEREMIQKE CAAIRSSFRE EDNTYRCRNV
60 70 80 90 100
AKLLYMHMLG YPAHFGQLEC LKLIASQKFT DKRIGYLGAM LLLDERQDVH
110 120 130 140 150
LLMTNCIKND LNHSTQFVQG LALCTLGCMG SSEMCRDLAG EVEKLLKTSN
160 170 180 190 200
SYLRKKAALC AVHVIRKVPE LMEMFLPATK NLLNEKNHGV LHTSVVLLTE
210 220 230 240 250
MCERSPDMLA HFRKNEKLVP QLVRILKNLI MSGYSPEHDV SGISDPFLQV
260 270 280 290 300
RILRLLRILG RNDDDSSEAM NDILAQVATN TETSKNVGNA ILYETVLTIM
310 320 330 340 350
DIKSESGLRV LAINILGRFL LNNDKNIRYV ALTSLLKTVQ TDHNAVQRHR
360 370 380 390 400
STIVDCLKDL DVSIKRRAME LSFALVNGNN IRGMMKELLY FLDSCEPEFK
410 420 430 440 450
ADCASGIFLA AEKYAPSKRW HIDTIMRVLT TAGSYVRDDA VPNLIQLITN
460 470 480 490 500
SVEMHAYTVQ RLYKAILGDY SQQPLVQVAA WCIGEYGDLL VSGQCEEEEP
510 520 530 540 550
IQVTEDEVLD ILESVLISNM STSVTRGYAL TAIMKLSTRF TCTVNRIKKV
560 570 580 590 600
VSIYGSSIDV ELQQRAVEYN ALFKKYDHMR SALLERMPVM EKVTTNGPSE
610 620 630 640 650
IVQTNGETEP APLETKPPPS GPQPTSQAND LLDLLGGNDI TPVIPTAPTS
660 670 680 690 700
KPASAGGELL DLLGDITLTG APAAAPTPAS VPQISQPPFL LDGLSSQPLF
710 720 730 740 750
NDIAPGIPSI TAYSKNGLKI EFTFERSNTN PSVTVITIQA SNSTELDMTD
760 770 780 790 800
FVFQAAVPKT FQLQLLSPSS SVVPAFNTGT ITQVIKVLNP QKQQLRMRIK
810 820
LTYNHKGSAM QDLAEVNNFP PQSWQ
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP22892 | AP1G1_MOUSE | AP-1 complex subunit gamma-1 | Ap1g1 Adtg, Clapg1 | 822 | Annotation score: | ||
Q3TDN1 | Q3TDN1_MOUSE | AP-1 complex subunit gamma-1 | Ap1g1 | 49 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122807 Genomic DNA No translation available. AC132138 Genomic DNA No translation available. BC052703 mRNA Translation: AAH52703.1 BC054535 mRNA Translation: AAH54535.1 AK036387 mRNA Translation: BAC29406.1 |
RefSeqi | NP_033807.2, NM_009677.6 |
Genome annotation databases
Ensembli | ENSMUST00000093157; ENSMUSP00000090844; ENSMUSG00000031731 |
GeneIDi | 11765 |
UCSCi | uc033jhp.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC122807 Genomic DNA No translation available. AC132138 Genomic DNA No translation available. BC052703 mRNA Translation: AAH52703.1 BC054535 mRNA Translation: AAH54535.1 AK036387 mRNA Translation: BAC29406.1 |
RefSeqi | NP_033807.2, NM_009677.6 |
3D structure databases
SMRi | Q8CBB7 |
ModBasei | Search... |
PTM databases
SwissPalmi | Q8CBB7 |
Proteomic databases
PRIDEi | Q8CBB7 |
Protocols and materials databases
Antibodypediai | 3960, 236 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000093157; ENSMUSP00000090844; ENSMUSG00000031731 |
GeneIDi | 11765 |
UCSCi | uc033jhp.2, mouse |
Organism-specific databases
CTDi | 164 |
MGIi | MGI:101919, Ap1g1 |
Phylogenomic databases
GeneTreei | ENSGT00950000182838 |
OMAi | ATWVIGE |
OrthoDBi | 250202at2759 |
TreeFami | TF300367 |
Miscellaneous databases
BioGRID-ORCSi | 11765, 3 hits in 12 CRISPR screens |
ChiTaRSi | Ap1g1, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000031731, Expressed in forelimb bud and 298 other tissues |
ExpressionAtlasi | Q8CBB7, baseline and differential |
Family and domain databases
Gene3Di | 1.25.10.10, 1 hit |
InterProi | View protein in InterPro IPR017107, AP1_complex_gsu IPR011989, ARM-like IPR016024, ARM-type_fold IPR002553, Clathrin/coatomer_adapt-like_N IPR008152, Clathrin_a/b/g-adaptin_app_Ig IPR013041, Clathrin_app_Ig-like_sf IPR008153, GAE_dom |
Pfami | View protein in Pfam PF01602, Adaptin_N, 1 hit PF02883, Alpha_adaptinC2, 1 hit |
PIRSFi | PIRSF037094, AP1_complex_gamma, 1 hit |
SMARTi | View protein in SMART SM00809, Alpha_adaptinC2, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit SSF49348, SSF49348, 1 hit |
PROSITEi | View protein in PROSITE PS50180, GAE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8CBB7_MOUSE | |
Accessioni | Q8CBB7Primary (citable) accession number: Q8CBB7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |