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UniProtKB - Q8CAV9 (Q8CAV9_MOUSE)
Protein
Protein-tyrosine-phosphatase
Gene
Ptpn14
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- protein tyrosine phosphatase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolaseARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:Ptpn14Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:102467, Ptpn14 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 306 | FERMInterPro annotationAdd BLAST | 286 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 744 – 775 | DisorderedSequence analysisAdd BLAST | 32 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 172 – 192 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
OrthoDBi | 144506at2759 |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit cd13188, FERM_C_PTPN14_PTPN21, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR019749, Band_41_domain IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR014392, PTP_non-rcpt_14/21 IPR041782, PTPN14/21_FERM_C IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit |
PIRSFi | PIRSF000934, Tyr-Ptase_nr14, 1 hit |
PRINTSi | PR00935, BAND41 |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF52799, SSF52799, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
i Sequence
Sequence statusi: Fragment.
Q8CAV9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPFGLKLRRT RRYNVLSKNC FVTRIRLLDS NVIECTLSVE STGQECLEAV
60 70 80 90 100
AQRLELRETH YFGLWFLSKS QQARWVELEK PLKKHLDKFA NEPLLFFGVM
110 120 130 140 150
FYVPNVSRLQ QEATRYQYYL QVKKDVLEGR LRCSLEQVIR LAGLAVQADF
160 170 180 190 200
GDYNQFDSQE FLREYVLFPM DLAMEEAALE ELTQKVAQEH KAHSGILPAE
210 220 230 240 250
AELMYINEVE RLDGFGQEIF PVKDSHGNSV HLGIFFMGIF VRNRVGRQAV
260 270 280 290 300
IYRWNDIGSV THSKAAILLE LIDKEETALF HTDDIENAKY ISRLFTTRHK
310 320 330 340 350
FYKQNKICTE QSNSPPPIRR QPTWSRSSLP RQQPYILPPM HVQCSEHYSE
360 370 380 390 400
THTSQDSIFP GNEEALYCRS HNSLDLNYLN GTVTNGSVCS VHSVNSLSCS
410 420 430 440 450
QSFIQASPVS SNLSIPGSDI MRADYIPSHR HSTIIVPSYR PTPDYETVMR
460 470 480 490 500
QMKRGLMHAD SQSRSLRNLN IINTHAYNQP EELVYSQPEM RERHPYTVPY
510 520 530 540 550
AHQGCYGHKL VSPSDQMNPQ NCAMPIKPGA SSISHTVSTP ELANMQLQGA
560 570 580 590 600
QHYSTAHMLK NYLFRPPPPY PRPRPATSTP DLASHRHKYV SGSSPDLVTR
610 620 630 640 650
KVQLSVKTFQ EDSSPVVHQS LQEVSEPLTA TKHHGGGGGT VNKRHSLEVM
660 670 680 690 700
NSMVRGMEAM TLKSLNIPMA RRNTLREQGP SEETGGHEVH GLPQYHHKKT
710 720 730 740 750
FSDATMLIHS SESEEEEETL EAAPQVPVLR EKVEYSAQLQ AALARIPNRP
760 770 780 790 800
PPEYPGPRKS VSNGALRQDQ GTPLPAMARC RVLRHGPSKA LSVSRAEQLA
810 820 830 840 850
VNGASLGPSI SEPDLTSVKE RVKKEPVKER PVSEMFSLED SIIEREMMIR
860 870 880 890 900
NLEKQKMTGP QAQKRPLMLA ALNGLSVARV SGREDGHHDA TRVPIDERLR
910 920 930 940 950
ALKKKLEDGM VFTEYEQIPN KKANGVFSTA TLPENAERSR IREVVPYEEN
RVELIPT
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 957 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK037646 mRNA Translation: BAC29840.1 |
RefSeqi | NP_033002.2, NM_008976.2 |
Genome annotation databases
GeneIDi | 19250 |
KEGGi | mmu:19250 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK037646 mRNA Translation: BAC29840.1 |
RefSeqi | NP_033002.2, NM_008976.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q8CAV9 |
Protocols and materials databases
DNASUi | 19250 |
Genome annotation databases
GeneIDi | 19250 |
KEGGi | mmu:19250 |
Organism-specific databases
CTDi | 5784 |
MGIi | MGI:102467, Ptpn14 |
Phylogenomic databases
OrthoDBi | 144506at2759 |
Miscellaneous databases
BioGRID-ORCSi | 19250, 0 hits in 67 CRISPR screens |
ChiTaRSi | Ptpn14, mouse |
SOURCEi | Search... |
Gene expression databases
Genevisiblei | Q8CAV9, MM |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit cd13188, FERM_C_PTPN14_PTPN21, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR019749, Band_41_domain IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR029021, Prot-tyrosine_phosphatase-like IPR014392, PTP_non-rcpt_14/21 IPR041782, PTPN14/21_FERM_C IPR029071, Ubiquitin-like_domsf |
Pfami | View protein in Pfam PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit |
PIRSFi | PIRSF000934, Tyr-Ptase_nr14, 1 hit |
PRINTSi | PR00935, BAND41 |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF52799, SSF52799, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8CAV9_MOUSE | |
Accessioni | Q8CAV9Primary (citable) accession number: Q8CAV9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | January 19, 2022 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |