UniProtKB - Q8CAS3 (Q8CAS3_MOUSE)
Protein
Cyclin-C
Gene
Ccnc
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- cyclin-dependent protein serine/threonine kinase regulator activity Source: InterPro
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: InterPro
Keywordsi
Molecular function | CyclinUniRule annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Cyclin-CARBA annotation |
Gene namesi | Name:CcncImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1858199, Ccnc |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- mediator complex Source: InterPro
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000028252, Expressed in meninx and 305 other tissues |
ExpressionAtlasi | Q8CAS3, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 46 – 144 | CYCLINInterPro annotationAdd BLAST | 99 | |
Domaini | 157 – 236 | CYCLINInterPro annotationAdd BLAST | 80 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 253 – 282 | DisorderedSequence analysisAdd BLAST | 30 |
Sequence similaritiesi
Belongs to the cyclin family.UniRule annotation
Phylogenomic databases
GeneTreei | ENSGT00940000155625 |
OrthoDBi | 1079428at2759 |
Family and domain databases
CDDi | cd00043, CYCLIN, 2 hits |
InterProi | View protein in InterPro IPR013763, Cyclin-like IPR036915, Cyclin-like_sf IPR043198, Cyclin/Ssn8 IPR006671, Cyclin_N IPR028367, CyclinC/Ssn8 |
PANTHERi | PTHR10026, PTHR10026, 1 hit PTHR10026:SF7, PTHR10026:SF7, 1 hit |
Pfami | View protein in Pfam PF00134, Cyclin_N, 1 hit |
SMARTi | View protein in SMART SM00385, CYCLIN, 2 hits |
SUPFAMi | SSF47954, SSF47954, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q8CAS3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAGNFWQSSH YLQWILDKQD LLKERQKDLK FLSEEEYWKL QIFFTNVIQA
60 70 80 90 100
LGEHLKLRQQ VIATATVYFK RFYARYSLKS IDPVLMAPTC VFLASKVEEF
110 120 130 140 150
GVVSNTRLIA ATTSVLKTRF SYAFPKEFPY RMNHILECEF YLLELMDCCL
160 170 180 190 200
IVYHPYRPLL QYVQDMGQED VLLPLAWRIV NDTYRTDLCL LYPPFMIALA
210 220 230 240 250
CLHVACVVQQ KDARQWFAEL SVDMEKILEI IRVILKLYEQ WKNFDERKEM
260 270 280
ATILSKMPKP KPPPNRSSLS DSPLMAGPEA AR
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ62447 | CCNC_MOUSE | Cyclin-C | Ccnc | 283 | Annotation score: | ||
Q3UXL9 | Q3UXL9_MOUSE | Cyclin-C | Ccnc | 266 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL772187 Genomic DNA No translation available. AK037957 mRNA Translation: BAC29908.1 |
RefSeqi | NP_001116454.1, NM_001122982.2 NP_001277349.1, NM_001290420.1 NP_001277351.1, NM_001290422.1 NP_058026.2, NM_016746.4 |
Genome annotation databases
Ensembli | ENSMUST00000065928; ENSMUSP00000069076; ENSMUSG00000028252 ENSMUST00000108240; ENSMUSP00000103875; ENSMUSG00000028252 |
GeneIDi | 51813 |
KEGGi | mmu:51813 |
UCSCi | uc008scs.3, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL772187 Genomic DNA No translation available. AK037957 mRNA Translation: BAC29908.1 |
RefSeqi | NP_001116454.1, NM_001122982.2 NP_001277349.1, NM_001290420.1 NP_001277351.1, NM_001290422.1 NP_058026.2, NM_016746.4 |
3D structure databases
SMRi | Q8CAS3 |
ModBasei | Search... |
Proteomic databases
PRIDEi | Q8CAS3 |
Protocols and materials databases
Antibodypediai | 4188, 325 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000065928; ENSMUSP00000069076; ENSMUSG00000028252 ENSMUST00000108240; ENSMUSP00000103875; ENSMUSG00000028252 |
GeneIDi | 51813 |
KEGGi | mmu:51813 |
UCSCi | uc008scs.3, mouse |
Organism-specific databases
CTDi | 892 |
MGIi | MGI:1858199, Ccnc |
Phylogenomic databases
GeneTreei | ENSGT00940000155625 |
OrthoDBi | 1079428at2759 |
Miscellaneous databases
BioGRID-ORCSi | 51813, 11 hits in 21 CRISPR screens |
ChiTaRSi | Ccnc, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000028252, Expressed in meninx and 305 other tissues |
ExpressionAtlasi | Q8CAS3, baseline and differential |
Family and domain databases
CDDi | cd00043, CYCLIN, 2 hits |
InterProi | View protein in InterPro IPR013763, Cyclin-like IPR036915, Cyclin-like_sf IPR043198, Cyclin/Ssn8 IPR006671, Cyclin_N IPR028367, CyclinC/Ssn8 |
PANTHERi | PTHR10026, PTHR10026, 1 hit PTHR10026:SF7, PTHR10026:SF7, 1 hit |
Pfami | View protein in Pfam PF00134, Cyclin_N, 1 hit |
SMARTi | View protein in SMART SM00385, CYCLIN, 2 hits |
SUPFAMi | SSF47954, SSF47954, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q8CAS3_MOUSE | |
Accessioni | Q8CAS3Primary (citable) accession number: Q8CAS3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 1, 2003 |
Last sequence update: | March 1, 2003 | |
Last modified: | February 10, 2021 | |
This is version 138 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |