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Protein

Ras-related protein Rab-36

Gene

Rab36

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Protein transport. Probably involved in vesicular traffic (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi64 – 71GTPBy similarity8
Nucleotide bindingi112 – 116GTPBy similarity5
Nucleotide bindingi171 – 174GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport
LigandGTP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-6811438 Intra-Golgi traffic
R-MMU-8873719 RAB geranylgeranylation

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-related protein Rab-36
Gene namesi
Name:Rab36
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1924127 Rab36

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003152371 – 267Ras-related protein Rab-36Add BLAST267

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi266S-geranylgeranyl cysteineSequence analysis1
Lipidationi267S-geranylgeranyl cysteineSequence analysis1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

MaxQBiQ8CAM5
PaxDbiQ8CAM5
PRIDEiQ8CAM5

PTM databases

iPTMnetiQ8CAM5
PhosphoSitePlusiQ8CAM5

Expressioni

Gene expression databases

BgeeiENSMUSG00000020175 Expressed in 161 organ(s), highest expression level in embryo
CleanExiMM_RAB36
ExpressionAtlasiQ8CAM5 baseline and differential
GenevisibleiQ8CAM5 MM

Interactioni

Protein-protein interaction databases

IntActiQ8CAM5, 7 interactors
STRINGi10090.ENSMUSP00000020391

Structurei

3D structure databases

ProteinModelPortaliQ8CAM5
SMRiQ8CAM5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi86 – 94Effector regionBy similarity9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

eggNOGiKOG0094 Eukaryota
ENOG410XPBI LUCA
GeneTreeiENSGT00910000144073
HOGENOMiHOG000233970
HOVERGENiHBG106693
InParanoidiQ8CAM5
OMAiQTLEHTR
OrthoDBiEOG091G0EPX
PhylomeDBiQ8CAM5
TreeFamiTF326626

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q8CAM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSSWTPLGP PVSQDRIITS FPKWYTPDAC LQLKEHFHSR VSTACQHRNT
60 70 80 90 100
GTAGLRLSKV VVVGDLYVGK TSLIHRLCKN VFDHDYKATI GVDFEIERFE
110 120 130 140 150
IAGIPYSLQI WDTAGQEKFK CIASAYYRGA QVIITAFDLT DVQTLEHTRQ
160 170 180 190 200
WLEDVLRENE AGSCFIFLVG TKKDLLSGAA CEQAEAEAVH LANEMQAEYW
210 220 230 240 250
SVSAKTGENV KAFFSRVAAL AFEQSVLQDL EKRPSTQSQV GDGDGDLIRI
260
EVPKTQENKR PPGLGCC
Length:267
Mass (Da):29,776
Last modified:March 1, 2003 - v1
Checksum:iE1D4B36A4BA598F0
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3YZ27D3YZ27_MOUSE
Ras-related protein Rab-36
Rab36
134Annotation score:
A0A1X7SB53A0A1X7SB53_MOUSE
Ras-related protein Rab-36
Rab36
101Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB232632 mRNA Translation: BAF02894.1
AK038445 mRNA Translation: BAC30001.1
AK046113 mRNA Translation: BAE20653.1
AK142025 mRNA Translation: BAE24917.1
BC119094 mRNA Translation: AAI19095.1
BC119098 mRNA Translation: AAI19099.1
CCDSiCCDS23923.1
RefSeqiNP_084057.1, NM_029781.3
XP_006514349.1, XM_006514286.1
XP_006514350.1, XM_006514287.1
XP_006514351.1, XM_006514288.1
XP_006514352.1, XM_006514289.1
XP_006514353.1, XM_006514290.1
XP_006514354.1, XM_006514291.1
XP_011241901.1, XM_011243599.1
UniGeneiMm.133593

Genome annotation databases

EnsembliENSMUST00000146440; ENSMUSP00000121693; ENSMUSG00000020175
ENSMUST00000147802; ENSMUSP00000119399; ENSMUSG00000020175
GeneIDi76877
UCSCiuc007fpx.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB232632 mRNA Translation: BAF02894.1
AK038445 mRNA Translation: BAC30001.1
AK046113 mRNA Translation: BAE20653.1
AK142025 mRNA Translation: BAE24917.1
BC119094 mRNA Translation: AAI19095.1
BC119098 mRNA Translation: AAI19099.1
CCDSiCCDS23923.1
RefSeqiNP_084057.1, NM_029781.3
XP_006514349.1, XM_006514286.1
XP_006514350.1, XM_006514287.1
XP_006514351.1, XM_006514288.1
XP_006514352.1, XM_006514289.1
XP_006514353.1, XM_006514290.1
XP_006514354.1, XM_006514291.1
XP_011241901.1, XM_011243599.1
UniGeneiMm.133593

3D structure databases

ProteinModelPortaliQ8CAM5
SMRiQ8CAM5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8CAM5, 7 interactors
STRINGi10090.ENSMUSP00000020391

PTM databases

iPTMnetiQ8CAM5
PhosphoSitePlusiQ8CAM5

Proteomic databases

MaxQBiQ8CAM5
PaxDbiQ8CAM5
PRIDEiQ8CAM5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000146440; ENSMUSP00000121693; ENSMUSG00000020175
ENSMUST00000147802; ENSMUSP00000119399; ENSMUSG00000020175
GeneIDi76877
UCSCiuc007fpx.1 mouse

Organism-specific databases

CTDi9609
MGIiMGI:1924127 Rab36

Phylogenomic databases

eggNOGiKOG0094 Eukaryota
ENOG410XPBI LUCA
GeneTreeiENSGT00910000144073
HOGENOMiHOG000233970
HOVERGENiHBG106693
InParanoidiQ8CAM5
OMAiQTLEHTR
OrthoDBiEOG091G0EPX
PhylomeDBiQ8CAM5
TreeFamiTF326626

Enzyme and pathway databases

ReactomeiR-MMU-6811438 Intra-Golgi traffic
R-MMU-8873719 RAB geranylgeranylation

Miscellaneous databases

PROiPR:Q8CAM5
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020175 Expressed in 161 organ(s), highest expression level in embryo
CleanExiMM_RAB36
ExpressionAtlasiQ8CAM5 baseline and differential
GenevisibleiQ8CAM5 MM

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51419 RAB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRAB36_MOUSE
AccessioniPrimary (citable) accession number: Q8CAM5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: March 1, 2003
Last modified: September 12, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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