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Protein

Protein shisa-4

Gene

Shisa4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein shisa-4
Alternative name(s):
Transmembrane protein 58
Gene namesi
Name:Shisa4
Synonyms:Tmem58
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1924802 Shisa4

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini28 – 87ExtracellularSequence analysisAdd BLAST60
Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
Topological domaini109 – 197CytoplasmicSequence analysisAdd BLAST89

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000025409128 – 197Protein shisa-4Add BLAST170

Proteomic databases

MaxQBiQ8CA71
PaxDbiQ8CA71
PeptideAtlasiQ8CA71
PRIDEiQ8CA71

PTM databases

iPTMnetiQ8CA71
PhosphoSitePlusiQ8CA71

Expressioni

Gene expression databases

BgeeiENSMUSG00000041889 Expressed in 216 organ(s), highest expression level in gastrocnemius
GenevisibleiQ8CA71 MM

Structurei

3D structure databases

SMRiQ8CA71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi131 – 195Pro-richAdd BLAST65

Sequence similaritiesi

Belongs to the shisa family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IGGX Eukaryota
ENOG4111ZPQ LUCA
GeneTreeiENSGT00730000111186
HOGENOMiHOG000036834
HOVERGENiHBG054420
InParanoidiQ8CA71
OMAiCGTCYQR
OrthoDBiEOG091G0MPG
PhylomeDBiQ8CA71
TreeFamiTF332572

Family and domain databases

InterProiView protein in InterPro
IPR026910 Shisa
PANTHERiPTHR31395 PTHR31395, 1 hit
PfamiView protein in Pfam
PF13908 Shisa, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8CA71-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPPAGPRGTA PLAAVVLLVL GAPLALASED CLWYLDRNGS WHPGFDCEFF
60 70 80 90 100
TFCCGTCYQR YCCRDLTLLI TERQQKHCLA FSPKTIAGIA SAVILFVAVV
110 120 130 140 150
ATTICCFLCS CCYLYRRRQQ LQSTFEGQEI PMTGIPMQPV YQYPPDPKAG
160 170 180 190
PAPPQPGFMY PPSGPAPQYP LYPAGPPIYN PAAPPPYMPP QPSYPGA
Length:197
Mass (Da):21,483
Last modified:March 1, 2003 - v1
Checksum:iA2E8D109A10DF639
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039457 mRNA Translation: BAC30354.1
BC044813 mRNA Translation: AAH44813.1
CCDSiCCDS15319.1
RefSeqiNP_780468.1, NM_175259.4
XP_006530014.1, XM_006529951.3
UniGeneiMm.41407

Genome annotation databases

EnsembliENSMUST00000041240; ENSMUSP00000046033; ENSMUSG00000041889
GeneIDi77552
KEGGimmu:77552
UCSCiuc007ctc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK039457 mRNA Translation: BAC30354.1
BC044813 mRNA Translation: AAH44813.1
CCDSiCCDS15319.1
RefSeqiNP_780468.1, NM_175259.4
XP_006530014.1, XM_006529951.3
UniGeneiMm.41407

3D structure databases

SMRiQ8CA71
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ8CA71
PhosphoSitePlusiQ8CA71

Proteomic databases

MaxQBiQ8CA71
PaxDbiQ8CA71
PeptideAtlasiQ8CA71
PRIDEiQ8CA71

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000041240; ENSMUSP00000046033; ENSMUSG00000041889
GeneIDi77552
KEGGimmu:77552
UCSCiuc007ctc.1 mouse

Organism-specific databases

CTDi149345
MGIiMGI:1924802 Shisa4

Phylogenomic databases

eggNOGiENOG410IGGX Eukaryota
ENOG4111ZPQ LUCA
GeneTreeiENSGT00730000111186
HOGENOMiHOG000036834
HOVERGENiHBG054420
InParanoidiQ8CA71
OMAiCGTCYQR
OrthoDBiEOG091G0MPG
PhylomeDBiQ8CA71
TreeFamiTF332572

Miscellaneous databases

PROiPR:Q8CA71
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041889 Expressed in 216 organ(s), highest expression level in gastrocnemius
GenevisibleiQ8CA71 MM

Family and domain databases

InterProiView protein in InterPro
IPR026910 Shisa
PANTHERiPTHR31395 PTHR31395, 1 hit
PfamiView protein in Pfam
PF13908 Shisa, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSHSA4_MOUSE
AccessioniPrimary (citable) accession number: Q8CA71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2003
Last modified: November 7, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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