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UniProtKB - Q8C8V1 (ZXDC_MOUSE)

Entry version 149 (23 Feb 2022)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
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Protein

Zinc finger protein ZXDC

Gene

Zxdc

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.

By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri176 – 200C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri209 – 233C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri239 – 263C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri269 – 291C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 322C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri329 – 353C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri359 – 383C2H2-type 7PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri389 – 413C2H2-type 8PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri419 – 443C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri452 – 477C2H2-type 10PROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein ZXDC
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zxdc
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1933108, Zxdc

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000034430

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002928041 – 858Zinc finger protein ZXDCAdd BLAST858

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki661Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Sumoylated at Lys-661 with SUMO1, SUMO2 and SUMO3; sumoylation enhances the activity of the transcriptional activation domain.By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q8C8V1

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q8C8V1

PRoteomics IDEntifications database

More...PRIDEi		Q8C8V1

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		275250 [Q8C8V1-1]
275251 [Q8C8V1-2]
275252 [Q8C8V1-3]
275253 [Q8C8V1-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q8C8V1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q8C8V1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000034430, Expressed in primary oocyte and 292 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q8C8V1, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q8C8V1, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-associates.

Interacts with ZXDB and CIITA (By similarity).

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000074619

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q8C8V1, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q8C8V1

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 73DisorderedSequence analysisAdd BLAST73
Regioni85 – 108DisorderedSequence analysisAdd BLAST24
Regioni142 – 175DisorderedSequence analysisAdd BLAST34
Regioni624 – 652DisorderedSequence analysisAdd BLAST29
Regioni671 – 714DisorderedSequence analysisAdd BLAST44
Regioni727 – 751DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi53 – 69Pro residuesSequence analysisAdd BLAST17
Compositional biasi677 – 713Polar residuesSequence analysisAdd BLAST37
Compositional biasi727 – 746Basic and acidic residuesSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ZXD family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri176 – 200C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri209 – 233C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri239 – 263C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri269 – 291C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 322C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri329 – 353C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri359 – 383C2H2-type 7PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri389 – 413C2H2-type 8PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri419 – 443C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri452 – 477C2H2-type 10PROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000162216

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_007312_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q8C8V1

Identification of Orthologs from Complete Genome Data

More...OMAi		QCAGSTI

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q8C8V1

TreeFam database of animal gene trees

More...TreeFami		TF330996

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 5 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8C8V1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLPAVLAAP ATRGDQHGGG PSRLRRGAGP SLGAGPGRRR LLLLRGPEDG 
        60         70         80         90        100
GPGPRPEEAP GPSPPPPEDG GDSFVVLLEV PRAADTHGQE EAEPDSGASP 
       110        120        130        140        150
TEQVPAAAPG AALAGTVTIH NQDLLVRFDR GVFTLAAAPA PAAPSLHPAT 
       160        170        180        190        200
TPGLEPSSAA ASRRGPVAAS AGSPAYRCPE PQCALSFAKK HQLKVHLLTH 
       210        220        230        240        250
GSLQGRRPFK CPLDGCGWAF TTSYKLKRHL QSHDKLRPFS CPVGGCGKKF 
       260        270        280        290        300
TTVYNLKAHM KGHEQESLFK CEVCAERFPT HAKLNSHQRS HFEPERPYKC 
       310        320        330        340        350
DFPGCEKTFI TVSALFSHNR AHFREQELFS CSFPGCNKQY DKACRLKIHL 
       360        370        380        390        400
RSHTGERPFI CDSDSCGWTF TSMSKLLRHK RKHDDDRRFT CPVEGCGKSF 
       410        420        430        440        450
TRAEHLKGHS ITHLGTKPFE CPVEGCCARF SARSSLYIHS KKHLQDVGTP 
       460        470        480        490        500
KSRCPVSSCN RLFTSKHSMK AHVVRQHSRR QDLVPQLEAP SSLTPSSELS 
       510        520        530        540        550
SPGQSELTNI DLAALFSDTP ANSSSSTAGS DEALNSGILT IDVTSVSSSL 
       560        570        580        590        600
GGNLPTNNNS LGPMDPLVLV AHGDMPPSLD SPLVLGTSAT VLQPGSFSAD 
       610        620        630        640        650
DSQAMSTGAV GCLVALPVRN LNQDSPALTP SNNLTAPGTT PTSSDTTQET 
       660        670        680        690        700
GSVPDLLVPI KVEQDLSPVP DVVQGQKESH GPSQSVLSSS TERPGAQKDS 
       710        720        730        740        750
ELSAGTGSLY LESGGSARTD YRAIQLVKKK KQKGTGSDEG ASDSAHRKVK 
       760        770        780        790        800
GGTINPPHVH SGQHSCFCGT LMVPSGGLTV PAPAAGLQCV QIPVLQDDPS 
       810        820        830        840        850
GEGGLPLGLS PQRSAFHPYF TVDLPVYVLQ EVLPAPGGFA GLETAQVPGS 

TINLRDLE
Length:858
Mass (Da):90,755
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA7B31AFE64907C3B
GO
Isoform 2 (identifier: Q8C8V1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     712-712: E → V
     713-858: Missing.

Show »
Length:712
Mass (Da):75,647
Checksum:i4AE84A5E999223C5
GO
Isoform 3 (identifier: Q8C8V1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     505-512: SELTNIDL → RKWGLSKN
     513-858: Missing.

Show »
Length:512
Mass (Da):55,723
Checksum:i9197279E9EA609A7
GO
Isoform 4 (identifier: Q8C8V1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     356-363: ERPFICDS → MSCSVHLM
     364-858: Missing.

Show »
Length:363
Mass (Da):38,909
Checksum:i3C55853A64055511
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0N4SV82A0A0N4SV82_MOUSE
Zinc finger protein ZXDC
Zxdc
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH03332 differs from that shown. Reason: Frameshift.Curated
The sequence BAC31967 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAC33082 differs from that shown. Reason: Frameshift.Curated
The sequence BAC38113 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti154L → Q in BAE24766 (PubMed:16141072).Curated1
Sequence conflicti576P → R in BAC38113 (PubMed:16141072).Curated1
Sequence conflicti608G → V in BAC37873 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026439356 – 363ERPFICDS → MSCSVHLM in isoform 4. 1 Publication8
Alternative sequenceiVSP_026440364 – 858Missing in isoform 4. 1 PublicationAdd BLAST495
Alternative sequenceiVSP_026441505 – 512SELTNIDL → RKWGLSKN in isoform 3. 1 Publication8
Alternative sequenceiVSP_026442513 – 858Missing in isoform 3. 1 PublicationAdd BLAST346
Alternative sequenceiVSP_026443712E → V in isoform 2. 2 Publications1
Alternative sequenceiVSP_026444713 – 858Missing in isoform 2. 2 PublicationsAdd BLAST146

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK044429 mRNA Translation: BAC31914.1
AK044529 mRNA Translation: BAC31967.1 Different initiation.
AK047538 mRNA Translation: BAC33082.1 Frameshift.
AK080307 mRNA Translation: BAC37873.1
AK081005 mRNA Translation: BAC38113.1 Different initiation.
AK141613 mRNA Translation: BAE24766.1
AK169517 mRNA Translation: BAE41206.1
BC003332 mRNA Translation: AAH03332.1 Frameshift.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS20358.1 [Q8C8V1-1]
CCDS51848.1 [Q8C8V1-2]

NCBI Reference Sequences

More...RefSeqi		NP_084536.2, NM_030260.3 [Q8C8V1-2]
NP_766590.1, NM_173002.3 [Q8C8V1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000045740; ENSMUSP00000036329; ENSMUSG00000034430 [Q8C8V1-3]
ENSMUST00000075117; ENSMUSP00000074619; ENSMUSG00000034430 [Q8C8V1-1]
ENSMUST00000113539; ENSMUSP00000109167; ENSMUSG00000034430 [Q8C8V1-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		80292

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:80292

UCSC genome browser

More...UCSCi		uc009cxf.2, mouse [Q8C8V1-1]
uc012eoy.1, mouse [Q8C8V1-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK044429 mRNA Translation: BAC31914.1
AK044529 mRNA Translation: BAC31967.1 Different initiation.
AK047538 mRNA Translation: BAC33082.1 Frameshift.
AK080307 mRNA Translation: BAC37873.1
AK081005 mRNA Translation: BAC38113.1 Different initiation.
AK141613 mRNA Translation: BAE24766.1
AK169517 mRNA Translation: BAE41206.1
BC003332 mRNA Translation: AAH03332.1 Frameshift.
CCDSiCCDS20358.1 [Q8C8V1-1]
CCDS51848.1 [Q8C8V1-2]
RefSeqiNP_084536.2, NM_030260.3 [Q8C8V1-2]
NP_766590.1, NM_173002.3 [Q8C8V1-1]

3D structure databases

SMRiQ8C8V1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074619

PTM databases

iPTMnetiQ8C8V1
PhosphoSitePlusiQ8C8V1

Proteomic databases

MaxQBiQ8C8V1
PaxDbiQ8C8V1
PRIDEiQ8C8V1
ProteomicsDBi275250 [Q8C8V1-1]
275251 [Q8C8V1-2]
275252 [Q8C8V1-3]
275253 [Q8C8V1-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		33073, 110 antibodies from 20 providers

The DNASU plasmid repository

More...DNASUi		80292

Genome annotation databases

EnsembliENSMUST00000045740; ENSMUSP00000036329; ENSMUSG00000034430 [Q8C8V1-3]
ENSMUST00000075117; ENSMUSP00000074619; ENSMUSG00000034430 [Q8C8V1-1]
ENSMUST00000113539; ENSMUSP00000109167; ENSMUSG00000034430 [Q8C8V1-2]
GeneIDi80292
KEGGimmu:80292
UCSCiuc009cxf.2, mouse [Q8C8V1-1]
uc012eoy.1, mouse [Q8C8V1-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		79364
MGIiMGI:1933108, Zxdc
VEuPathDBiHostDB:ENSMUSG00000034430

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162216
HOGENOMiCLU_007312_0_0_1
InParanoidiQ8C8V1
OMAiQCAGSTI
OrthoDBi1318335at2759
PhylomeDBiQ8C8V1
TreeFamiTF330996

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		80292, 1 hit in 64 CRISPR screens

Protein Ontology

More...PROi		PR:Q8C8V1
RNActiQ8C8V1, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000034430, Expressed in primary oocyte and 292 other tissues
ExpressionAtlasiQ8C8V1, baseline and differential
GenevisibleiQ8C8V1, MM

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 10 hits
SUPFAMiSSF57667, SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 10 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZXDC_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C8V1
Secondary accession number(s): Q3TEP2
, Q3URC2, Q8C4U7, Q8C4Z9, Q8C8C2, Q8C8T1, Q99J65
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: March 1, 2003
Last modified: February 23, 2022
This is version 149 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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