Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 141 (22 Apr 2020)
Sequence version 1 (01 Mar 2003)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein ZXDC

Gene

Zxdc

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri176 – 200C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri209 – 233C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri239 – 263C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri269 – 291C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 322C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri329 – 353C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri359 – 383C2H2-type 7PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri389 – 413C2H2-type 8PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri419 – 443C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri452 – 477C2H2-type 10PROSITE-ProRule annotationAdd BLAST26

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein ZXDC
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Zxdc
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1933108 Zxdc

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002928041 – 858Zinc finger protein ZXDCAdd BLAST858

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki661Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Sumoylated at Lys-661 with SUMO1, SUMO2 and SUMO3; sumoylation enhances the activity of the transcriptional activation domain.By similarity

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q8C8V1

PRoteomics IDEntifications database

More...
PRIDEi
Q8C8V1

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q8C8V1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q8C8V1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000034430 Expressed in primary oocyte and 268 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q8C8V1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q8C8V1 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Self-associates.

Interacts with ZXDB and CIITA (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000074619

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q8C8V1 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q8C8V1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ZXD family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri176 – 200C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri209 – 233C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri239 – 263C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri269 – 291C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri298 – 322C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri329 – 353C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri359 – 383C2H2-type 7PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri389 – 413C2H2-type 8PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri419 – 443C2H2-type 9PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri452 – 477C2H2-type 10PROSITE-ProRule annotationAdd BLAST26

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162216

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007312_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q8C8V1

Identification of Orthologs from Complete Genome Data

More...
OMAi
PHICHFE

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q8C8V1

TreeFam database of animal gene trees

More...
TreeFami
TF330996

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q8C8V1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLPAVLAAP ATRGDQHGGG PSRLRRGAGP SLGAGPGRRR LLLLRGPEDG
60 70 80 90 100
GPGPRPEEAP GPSPPPPEDG GDSFVVLLEV PRAADTHGQE EAEPDSGASP
110 120 130 140 150
TEQVPAAAPG AALAGTVTIH NQDLLVRFDR GVFTLAAAPA PAAPSLHPAT
160 170 180 190 200
TPGLEPSSAA ASRRGPVAAS AGSPAYRCPE PQCALSFAKK HQLKVHLLTH
210 220 230 240 250
GSLQGRRPFK CPLDGCGWAF TTSYKLKRHL QSHDKLRPFS CPVGGCGKKF
260 270 280 290 300
TTVYNLKAHM KGHEQESLFK CEVCAERFPT HAKLNSHQRS HFEPERPYKC
310 320 330 340 350
DFPGCEKTFI TVSALFSHNR AHFREQELFS CSFPGCNKQY DKACRLKIHL
360 370 380 390 400
RSHTGERPFI CDSDSCGWTF TSMSKLLRHK RKHDDDRRFT CPVEGCGKSF
410 420 430 440 450
TRAEHLKGHS ITHLGTKPFE CPVEGCCARF SARSSLYIHS KKHLQDVGTP
460 470 480 490 500
KSRCPVSSCN RLFTSKHSMK AHVVRQHSRR QDLVPQLEAP SSLTPSSELS
510 520 530 540 550
SPGQSELTNI DLAALFSDTP ANSSSSTAGS DEALNSGILT IDVTSVSSSL
560 570 580 590 600
GGNLPTNNNS LGPMDPLVLV AHGDMPPSLD SPLVLGTSAT VLQPGSFSAD
610 620 630 640 650
DSQAMSTGAV GCLVALPVRN LNQDSPALTP SNNLTAPGTT PTSSDTTQET
660 670 680 690 700
GSVPDLLVPI KVEQDLSPVP DVVQGQKESH GPSQSVLSSS TERPGAQKDS
710 720 730 740 750
ELSAGTGSLY LESGGSARTD YRAIQLVKKK KQKGTGSDEG ASDSAHRKVK
760 770 780 790 800
GGTINPPHVH SGQHSCFCGT LMVPSGGLTV PAPAAGLQCV QIPVLQDDPS
810 820 830 840 850
GEGGLPLGLS PQRSAFHPYF TVDLPVYVLQ EVLPAPGGFA GLETAQVPGS

TINLRDLE
Length:858
Mass (Da):90,755
Last modified:March 1, 2003 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA7B31AFE64907C3B
GO
Isoform 2 (identifier: Q8C8V1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     712-712: E → V
     713-858: Missing.

Show »
Length:712
Mass (Da):75,647
Checksum:i4AE84A5E999223C5
GO
Isoform 3 (identifier: Q8C8V1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     505-512: SELTNIDL → RKWGLSKN
     513-858: Missing.

Show »
Length:512
Mass (Da):55,723
Checksum:i9197279E9EA609A7
GO
Isoform 4 (identifier: Q8C8V1-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     356-363: ERPFICDS → MSCSVHLM
     364-858: Missing.

Show »
Length:363
Mass (Da):38,909
Checksum:i3C55853A64055511
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0N4SV82A0A0N4SV82_MOUSE
Zinc finger protein ZXDC
Zxdc
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH03332 differs from that shown. Reason: Frameshift.Curated
The sequence BAC31967 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence BAC33082 differs from that shown. Reason: Frameshift.Curated
The sequence BAC38113 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti154L → Q in BAE24766 (PubMed:16141072).Curated1
Sequence conflicti576P → R in BAC38113 (PubMed:16141072).Curated1
Sequence conflicti608G → V in BAC37873 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026439356 – 363ERPFICDS → MSCSVHLM in isoform 4. 1 Publication8
Alternative sequenceiVSP_026440364 – 858Missing in isoform 4. 1 PublicationAdd BLAST495
Alternative sequenceiVSP_026441505 – 512SELTNIDL → RKWGLSKN in isoform 3. 1 Publication8
Alternative sequenceiVSP_026442513 – 858Missing in isoform 3. 1 PublicationAdd BLAST346
Alternative sequenceiVSP_026443712E → V in isoform 2. 2 Publications1
Alternative sequenceiVSP_026444713 – 858Missing in isoform 2. 2 PublicationsAdd BLAST146

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK044429 mRNA Translation: BAC31914.1
AK044529 mRNA Translation: BAC31967.1 Different initiation.
AK047538 mRNA Translation: BAC33082.1 Frameshift.
AK080307 mRNA Translation: BAC37873.1
AK081005 mRNA Translation: BAC38113.1 Different initiation.
AK141613 mRNA Translation: BAE24766.1
AK169517 mRNA Translation: BAE41206.1
BC003332 mRNA Translation: AAH03332.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20358.1 [Q8C8V1-1]
CCDS51848.1 [Q8C8V1-2]

NCBI Reference Sequences

More...
RefSeqi
NP_084536.2, NM_030260.3 [Q8C8V1-2]
NP_766590.1, NM_173002.3 [Q8C8V1-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000045740; ENSMUSP00000036329; ENSMUSG00000034430 [Q8C8V1-3]
ENSMUST00000075117; ENSMUSP00000074619; ENSMUSG00000034430 [Q8C8V1-1]
ENSMUST00000113539; ENSMUSP00000109167; ENSMUSG00000034430 [Q8C8V1-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80292

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:80292

UCSC genome browser

More...
UCSCi
uc009cxf.2 mouse [Q8C8V1-1]
uc012eoy.1 mouse [Q8C8V1-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK044429 mRNA Translation: BAC31914.1
AK044529 mRNA Translation: BAC31967.1 Different initiation.
AK047538 mRNA Translation: BAC33082.1 Frameshift.
AK080307 mRNA Translation: BAC37873.1
AK081005 mRNA Translation: BAC38113.1 Different initiation.
AK141613 mRNA Translation: BAE24766.1
AK169517 mRNA Translation: BAE41206.1
BC003332 mRNA Translation: AAH03332.1 Frameshift.
CCDSiCCDS20358.1 [Q8C8V1-1]
CCDS51848.1 [Q8C8V1-2]
RefSeqiNP_084536.2, NM_030260.3 [Q8C8V1-2]
NP_766590.1, NM_173002.3 [Q8C8V1-1]

3D structure databases

SMRiQ8C8V1
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000074619

PTM databases

iPTMnetiQ8C8V1
PhosphoSitePlusiQ8C8V1

Proteomic databases

PaxDbiQ8C8V1
PRIDEiQ8C8V1

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33073 97 antibodies

Genome annotation databases

EnsembliENSMUST00000045740; ENSMUSP00000036329; ENSMUSG00000034430 [Q8C8V1-3]
ENSMUST00000075117; ENSMUSP00000074619; ENSMUSG00000034430 [Q8C8V1-1]
ENSMUST00000113539; ENSMUSP00000109167; ENSMUSG00000034430 [Q8C8V1-2]
GeneIDi80292
KEGGimmu:80292
UCSCiuc009cxf.2 mouse [Q8C8V1-1]
uc012eoy.1 mouse [Q8C8V1-2]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79364
MGIiMGI:1933108 Zxdc

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000162216
HOGENOMiCLU_007312_0_0_1
InParanoidiQ8C8V1
OMAiPHICHFE
OrthoDBi1318335at2759
PhylomeDBiQ8C8V1
TreeFamiTF330996

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q8C8V1
RNActiQ8C8V1 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000034430 Expressed in primary oocyte and 268 other tissues
ExpressionAtlasiQ8C8V1 baseline and differential
GenevisibleiQ8C8V1 MM

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZXDC_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q8C8V1
Secondary accession number(s): Q3TEP2
, Q3URC2, Q8C4U7, Q8C4Z9, Q8C8C2, Q8C8T1, Q99J65
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: March 1, 2003
Last modified: April 22, 2020
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again